Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amanda Dutton"'
Autor:
Amanda Dutton, Ciaran B. Woodman, Marilyn B. Chukwuma, James I. K. Last, Wenbin Wei, Martina Vockerodt, Karl R. N. Baumforth, Joanne R. Flavell, Martin Rowe, A. Malcolm R. Taylor, Lawrence S. Young, Paul G. Murray
Publikováno v:
Blood. 109:2597-2603
Polycomb group (PcG) proteins are chromatin modifiers that are necessary for the maintenance and renewal of embryonic and adult stem cells. However, overexpression of the PcG protein, Bmi-1, causes lymphoma in transgenic mice. We show that Bmi-1 is u
Publikováno v:
Expert review of anticancer therapy. 6(6)
Hodgkin's lymphoma is one of the most common lymphoid cancers, particularly among young adults. Although there have been dramatic improvements in the treatment of Hodgkin's lymphoma, leading to high cure rates in some groups, current combination chem
Publikováno v:
Expert opinion on therapeutic targets. 10(1)
Protection from death receptor (DR)-mediated apoptosis has been proposed as an important step in the development of malignancy, enabling tumour cells not only to survive and escape antitumour immune responses, but also to develop resistance to chemot
Publikováno v:
The Journal of pathology. 205(4)
The molecular mechanisms underlying the pathogenesis of the malignant Hodgkin's/Reed–Sternberg (HRS) cells of Hodgkin's lymphoma (HL) are largely unknown. This study investigates the contribution of phosphatidyl-inositide 3 kinase (PI3-kinase) and
Autor:
Gary M. Reynolds, John J. O'Neil, Amanda Dutton, Anne E. Milner, Jane Starczynski, Lawrence S. Young, John C. Crocker, Paul Murray
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 101(17)
Hodgkin's lymphoma (HL) is characterized by the presence of malignant so-called Hodgkin's/Reed-Sternberg (HRS) cells, which display resistance to certain apoptotic stimuli, including a lack of sensitivity to Fas-mediated cell death. However, the mech
Publikováno v:
Molecular Biology in Cellular Pathology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c88a395efbfaab88d9f3ca7d04f184b2
https://doi.org/10.1002/0470867949.ch10
https://doi.org/10.1002/0470867949.ch10