Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Amanda Doucette"'
Autor:
Amanda Doucette
Publikováno v:
CMCL@EACL
A recurrent neural network model of phonological pattern learning is proposed. The model is a relatively simple neural network with one recurrent layer, and displays biases in learning that mimic observed biases in human learning. Single-feature patt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda2459b511d1502185c52c4eb5296d5
Autor:
Teresa A. Soucy, Peter G. Smith, Michael A. Milhollen, Allison J. Berger, James M. Gavin, Sharmila Adhikari, James E. Brownell, Kristine E. Burke, David P. Cardin, Stephen Critchley, Courtney A. Cullis, Amanda Doucette, James J. Garnsey, Jeffrey L. Gaulin, Rachel E. Gershman, Anna R. Lublinsky, Alice McDonald, Hirotake Mizutani, Usha Narayanan, Edward J. Olhava, Stephane Peluso, Mansoureh Rezaei, Michael D. Sintchak, Tina Talreja, Michael P. Thomas, Tary Traore, Stepan Vyskocil, Gabriel S. Weatherhead, Jie Yu, Julie Zhang, Lawrence R. Dick, Christopher F. Claiborne, Mark Rolfe, Joseph B. Bolen, Steven P. Langston
Publikováno v:
Nature. 458:732-736
The clinical development of an inhibitor of cellular proteasome function suggests that compounds targeting other components of the ubiquitin-proteasome system might prove useful for the treatment of human malignancies. NEDD8-activating enzyme (NAE) i
Autor:
Jeffrey Ecsedy, Zhi Li, Amanda Doucette, Wenhai Zhang, Sean Harrison, Lenny Dang, Ping Li, Trupti Lingaraj, John Donovan
Publikováno v:
SLAS Discovery. 13:906-911
The signaling pathways involving lipid kinase class I phosphatidylinositol 3-kinases (PI 3-kinases) regulate cell growth, proliferation, and survival. Class I PI 3-kinases catalyze the conversion of PI (4,5)P2 to PI (3,4,5)P3, which acts as a lipid s
Autor:
Michael B. Gravestock, Amanda Doucette, Lena A Grosser, Sheila Irene Hauck, C. Cederberg, Neil James Hales, Grace Poon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:337-340
Substitution of phenyl oxazolidinones with carbon-linked azoles resulted in the discovery of a new class of potent oxazolidinones that have excellent Gram-positive activity. In addition, replacement of the C-5 acetamide side chains with a 4-methyl tr
Publikováno v:
The Journal of Organic Chemistry. 67:3937-3940
The barrier to rotation and hydrogen bonding interactions of 2,2-dicyano-1-(N,N'-dimethylamino)vinylbenzene (1) were studied in a range of solvents. The barrier to rotation of 1 in chloroform was 14.8 kcal/mol and increased by 1.7 kcal/mol in a proti
Publikováno v:
Tetrahedron Letters. 42:2635-2638
A multi-step solid phase synthesis of 2-aminobenzimidazoles is described. The reaction sequence incorporates optically active α-amino acids to afford enantiomerically pure 2-aminobenzimidazoles with a chiral center adjacent to one of the heterocycli