Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Amanda Dicks"'
Autor:
Niek G. C. Bloks, Amanda Dicks, Zainab Harissa, Rob G. H. H. Nelissen, Ghazaleh Hajmousa, Yolande F. M. Ramos, Rodrigo Coutinho de Almeida, Farshid Guilak, Ingrid Meulenbelt
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Osteoarthritis (OA) is a complex, age-related multifactorial degenerative disease of diarthrodial joints marked by impaired mobility, joint stiffness, pain, and a significant decrease in quality of life. Among other risk factors,
Externí odkaz:
https://doaj.org/article/709c5477d58844cfa4f24af6d4e8ead4
Autor:
Chia-Lung Wu, Amanda Dicks, Nancy Steward, Ruhang Tang, Dakota B. Katz, Yun-Rak Choi, Farshid Guilak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Application of human induced pluripotent stem cells (hiPSCs) for tissue regeneration is hindered by off-target cell differentiation. Here, the authors use bulk and single cell RNA-sequencing to identify WNT and MITF as off-target hubs during chondrog
Externí odkaz:
https://doaj.org/article/4749da5248df4c6c9aa0688e0fb689a9
Autor:
Amanda Dicks, Chia-Lung Wu, Nancy Steward, Shaunak S. Adkar, Charles A. Gersbach, Farshid Guilak
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2020)
Abstract Background Articular cartilage shows little or no capacity for intrinsic repair, generating a critical need of regenerative therapies for joint injuries and diseases such as osteoarthritis. Human-induced pluripotent stem cells (hiPSCs) offer
Externí odkaz:
https://doaj.org/article/f36c5cf155da46bd94d57c44b06c5220
Autor:
Amanda, Dicks, Himanshi, Bhatia, Adam W, Clemens, Marissa C, Locke, Elizabeth A, Mueller, Daniel, Murphy, Nathan, Pomper, Anne E, Robinson, Kathleen M, Schoch
Publikováno v:
Nature biotechnology. 39(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bad927906ff01b9633e5738bab5e1b57
https://pubmed.ncbi.nlm.nih.gov/34621067
https://pubmed.ncbi.nlm.nih.gov/34621067
Autor:
Ruhang Tang, Dakota B Katz, Chia-Lung Wu, Amanda Dicks, Yun-Rak Choi, Nancy Steward, Farshid Guilak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The therapeutic application of human induced pluripotent stem cells (hiPSCs) for cartilage regeneration is largely hindered by the low yield of chondrocytes accompanied by unpredictable and heterogeneous off-target differentiation of cells during cho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e029da459b0ee935e47f2ee1aacfcd8f
https://doi.org/10.1530/ey.18.5.10
https://doi.org/10.1530/ey.18.5.10
Publikováno v:
Annals of the New York Academy of Sciences. 1440:36-53
Fatty acids (FAs) are potent organic compounds that not only can be used as an energy source during nutrient deprivation but are also involved in several essential signaling cascades in cells. Therefore, the balance of intake of different dietary FAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b2a3b2d66ee9f5a6df71e2f15a0c97
https://doi.org/10.1111/nyas.13999
https://doi.org/10.1111/nyas.13999
Autor:
Shaunak S. Adkar, Charles A. Gersbach, Chia-Lung Wu, Farshid Guilak, Amanda Dicks, Nancy Steward
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2020)
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2020)
BackgroundArticular cartilage shows little or no capacity for intrinsic repair, generating a critical need of regenerative therapies for joint injuries and diseases such as osteoarthritis. Human-induced pluripotent stem cells (hiPSCs) offer a promisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73adfaccceec5ba16d3d5cfe09d97ff6
https://doi.org/10.1186/s13287-020-01597-8
https://doi.org/10.1186/s13287-020-01597-8
Publikováno v:
Matrix Biology, 71-72, 40-50
Osteoarthritis is a painful joint disease characterized by progressive degeneration of the articular cartilage as well as associated changes to the subchondral bone, synovium, and surrounding joint tissues. While the effects of osteoarthritis on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe664d432aebabba3e477b67a864a23
https://doi.org/10.1016/j.matbio.2018.05.008
https://doi.org/10.1016/j.matbio.2018.05.008
Autor:
Shaunak S. Adkar, Adarsh R. Ettyreddy, Vincent P. Willard, Nidhi Bhutani, Amanda Dicks, Chia-Lung Wu, Charles A. Gersbach, Farshid Guilak, Nancy Steward
The differentiation of human induced pluripotent stem cells (hiPSCs) to prescribed cell fates enables the engineering of patient-specific tissue types, such as hyaline cartilage, for applications in regenerative medicine, disease modeling, and drug s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3a5cbe95a183b75e0cc26e2ef2d1ed
https://europepmc.org/articles/PMC6312762/
https://europepmc.org/articles/PMC6312762/
Publikováno v:
Journal of Agricultural and Resource Economics, Vol 36, Iss 3, Pp 573-593 (2011)
The Food Security and Rural Investment Act of 2002 included a new provision that allowed managed haying and grazing (including the harvest of biomass), if consistent with the conservation of soil, water quality, and wildlife habitat, in return for pa
Externí odkaz:
https://doaj.org/article/35fbee13d54b42b0b05636e3e90a446a