Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Amanda D. Worthy"'
Publikováno v:
The Journal of Organic Chemistry. 78:10494-10499
Through kinetic analysis and optimization, we report an improved resolution of terminal 1,2-diols via asymmetric silyl transfer. Because the reaction is a regiodivergent resolution, the monoprotected product could be isolated in excess of 95:5 er and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78939bf575a31bdd539f892b0fb3cb67
https://doi.org/10.1021/jo4012909
https://doi.org/10.1021/jo4012909
Publikováno v:
Journal of the American Chemical Society. 134:7321-7324
This paper demonstrates that the secondary hydroxyl can be functionalized in preference to the primary hydroxyl of a 1,2-diol. The site selectivity is achieved by using an enantioselective organic catalyst that is able to bond to the diol reversibly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679c68a73d7d7a6f975659f452d2e540
https://doi.org/10.1021/ja3027086
https://doi.org/10.1021/ja3027086
Publikováno v:
Angewandte Chemie International Edition. 50:8167-8171
The use of reversible covalent bonding is a common design feature in synthetic catalysts. For most synthetic catalysts, reversible covalent bonding is used to form a reactive intermediate thereby affording enhanced rate of reaction (e.g. enamine, imi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acbbb285c2e77a42f7198c4a4caad55
https://doi.org/10.1002/anie.201103470
https://doi.org/10.1002/anie.201103470
Publikováno v:
ChemInform. 45
Through kinetic analysis and optimization, we report an improved resolution of terminal 1,2-diols via asymmetric silyl transfer. Because the reaction is a regiodivergent resolution, the monoprotected product could be isolated in excess of 95:5 er and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c466c9fa69ab74f639019f6a39b22137
https://doi.org/10.1002/chin.201411197
https://doi.org/10.1002/chin.201411197
Publikováno v:
Journal of the American Chemical Society. 132:14757-14759
The synthesis of β-amino-aldehydes has been achieved through enantioselective hydroformylation of PMP-protected allylic amines. The reaction is accomplished by using a scalemic scaffolding ligand that covalently and reversibly binds to the substrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca1285895f79b4e2e5ab917f27e1fec
https://doi.org/10.1021/ja107433h
https://doi.org/10.1021/ja107433h
Publikováno v:
ChemInform. 43
Inducing an intramolecular reaction is a powerful means of accelerating reactions. Though this mechanism of catalysis is common in enzymes, it is underutilized in synthetic catalysts. This article outlines our group’s recent efforts to use reversib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c73dd1dfdd273093df0661b5b79ef71c
https://doi.org/10.1002/chin.201216240
https://doi.org/10.1002/chin.201216240
Inducing an intramolecular reaction is a powerful means of accelerating reactions. Though this mechanism of catalysis is common in enzymes, it is underutilized in synthetic catalysts. This article outlines our group’s recent efforts to use reversib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e46db64fa55c211e9dd900478f957a
https://europepmc.org/articles/PMC3940486/
https://europepmc.org/articles/PMC3940486/
Publikováno v:
ChemInform. 42
The synthesis of β-amino-aldehydes has been achieved through enantioselective hydroformylation of PMP-protected allylic amines. The reaction is accomplished by using a scalemic scaffolding ligand that covalently and reversibly binds to the substrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e55488e57edb9519aeedb0dfd167dfef
https://doi.org/10.1002/chin.201109051
https://doi.org/10.1002/chin.201109051
Publikováno v:
ChemInform. 40
A highly regioselective hydroformylation of allylic sulfonamides has been developed by employing a catalytic directing group. The reaction tolerates a wide range of electronically and sterically modified olefins, and only 10% of the scaffolding ligan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e64e612f7dab530f43329fa7cd7268e
https://doi.org/10.1002/chin.200946081
https://doi.org/10.1002/chin.200946081
Autor:
Matthew J. Kier, George E. Greco, Tiffany A. Lowery, Shoshanah A. Gibbs, Lisa B. Hollander, Brittany L. Gleason, Amanda D. Worthy
Publikováno v:
Organic letters. 9(19)
Carbon dioxide undergoes a Pd-catalyzed [3+2] cycloaddition with trimethylenemethane (TMM) under mild conditions (1 atm, 75 degrees C, 30 min) to produce a gamma-butyrolactone product in 63% yield, when the Pd-TMM complex is generated from 2-(acetoxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d1d53b1293e86c86d46eee69bda046
https://pubmed.ncbi.nlm.nih.gov/17715934
https://pubmed.ncbi.nlm.nih.gov/17715934