Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain.

Autor: Helen M Wise, Edward C Hutchinson, Brett W Jagger, Amanda D Stuart, Zi H Kang, Nicole Robb, Louis M Schwartzman, John C Kash, Ervin Fodor, Andrew E Firth, Julia R Gog, Jeffery K Taubenberger, Paul Digard

Publikováno v: PLoS Pathogens, Vol 8, Iss 11, p e1002998 (2012)

Segment 7 of influenza A virus produces up to four mRNAs. Unspliced transcripts encode M1, spliced mRNA2 encodes the M2 ion channel, while protein products from spliced mRNAs 3 and 4 have not previously been identified. The M2 protein plays important

Externí odkaz: https://doaj.org/article/3bc38a0a2aa347b38bdcccc4ca32f8e7

Decay-accelerating factor binding determines the entry route of echovirus 11 in polarized epithelial cells

Autor: Amanda D. Stuart, Laura Rubbia-Brandt, Komla Sobo, Thomas Alexander Mckee, T. D. K. Brown

Publikováno v: Journal of virology
Journal of Virology, Vol. 85, No 23 (2011) pp. 12376-86

The interaction between echovirus 11 strain 207 (EV11-207) and decay-accelerating factor (DAF or CD55) at the apical surface of polarized Caco-2 cells results in rapid transport of the virus to tight junctions and in its subsequent uptake. A virus mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57479a5d099016dde6270930e6c322f3

Entry of Feline Calicivirus Is Dependent on Clathrin-Mediated Endocytosis and Acidification in Endosomes

Autor: Amanda D. Stuart, T. David K. Brown

Publikováno v: Journal of Virology. 80:7500-7509

Feline calicivirus is a major causative agent of respiratory disease in cats. It is also one of the few cultivatable members of Caliciviridae . We have examined the entry process of feline calicivirus (FCV). An earlier study demonstrated that acidifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61520d7bad2a00781606d2ccb7909288
https://doi.org/10.1128/jvi.02452-05

Phospholipase D Facilitates Efficient Entry of Influenza Virus, Allowing Escape from Innate Immune Inhibition*

Autor: Shalini Sharma, Sarah A. Scott, Thomas H. Oguin, H. Alex Brown, Paul G. Thomas, Carrie K. Jones, J. Scott Daniels, Susu Duan, Amanda D. Stuart, Craig W. Lindsley

Lipid metabolism plays a fundamental role during influenza virus replication, although key regulators of lipid-dependent trafficking and virus production remain inadequately defined. This report demonstrates that infection by influenza virus stimulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79900c439fea9fe6987ff9bb9156ba23
https://europepmc.org/articles/PMC4162146/

Identification of a Novel Splice Variant Form of the Influenza A Virus M2 Ion Channel with an Antigenically Distinct Ectodomain

Autor: Amanda D. Stuart, Edward C. Hutchinson, Zi H. Kang, Paul Digard, Nicole C. Robb, Louis M. Schwartzman, John C. Kash, Helen M. Wise, Brett W. Jagger, Jeffery K. Taubenberger, Ervin Fodor, Andrew E. Firth, Julia R. Gog

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 8, Iss 11, p e1002998 (2012)
Wise, H M, Hutchinson, E C, Jagger, B W, Stuart, A D, Kang, Z H, Robb, N, Schwartzman, L M, Kash, J C, Fodor, E, Firth, A E, Gog, J R, Taubenberger, J K & Digard, P 2012, ' Identification of a novel splice variant form of the influenza a virus m2 ion channel with an antigenically distinct ectodomain ', PLoS Pathogens, vol. 8, no. 11, e1002998 . https://doi.org/10.1371/journal.ppat.1002998

Segment 7 of influenza A virus produces up to four mRNAs. Unspliced transcripts encode M1, spliced mRNA2 encodes the M2 ion channel, while protein products from spliced mRNAs 3 and 4 have not previously been identified. The M2 protein plays important

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b6eee62483b432d05e88d644f635f8
http://europepmc.org/articles/PMC3486900