Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Amanda Chargin"'
Autor:
Devon Chabot-Richards, Amanda Chargin, Bruce K. Patterson, Aaron Wagner, Christen Griego-Fullbright, Stephen G. Young
Publikováno v:
American Journal of Clinical Pathology. 150:346-352
ObjectivesWe report on the validity of a fully quantitative technology to determine tumor cells’ PD-L1 expression compared with a standard immunohistochemical (IHC) assay in non–small cell lung cancer.MethodsNineteen fresh tissue specimens were p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ed1b8ca93c730a7b15702865bb5e40
https://doi.org/10.1093/ajcp/aqy063
https://doi.org/10.1093/ajcp/aqy063
Autor:
Amanda Chargin, Fangfang Yin, Min Song, Srividyabhuvaneswari Subramaniam, Grace Elaine Knutson, Bruce K. Patterson
Publikováno v:
Journal of Clinical Microbiology. 53:60-66
Plasma viral load and CD4 counts are effective for clinical monitoring, but they do not give a full representation of HIV-1 quasispecies in cellular reservoirs, the major repository of replication-competent HIV-1 in infected individuals. We sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e7721e372407487811a308528247e9
https://doi.org/10.1128/jcm.02539-14
https://doi.org/10.1128/jcm.02539-14
Autor:
Ming Ding, Jennifer M. Zerbato, Bruce K. Patterson, Nicolas Sluis-Cremer, Phalguni Gupta, Anwesha Sanyal, Amanda Chargin, Narasimhan J. Venkatachari, Nicholas S. Giacobbi, Deena Ratner, Yue Chen, Charles R. Rinaldo, Robbie B. Mailliard
Publikováno v:
Nature medicine
Although antiretroviral therapy can suppress HIV-1 infection to undetectable levels of plasma viremia, integrated latent HIV-1 genomes that encode replication competent virus persist in resting CD4+ T cells. This latent HIV-1 reservoir represents a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8defba603aaed24ef140385c7e540b66
https://pubmed.ncbi.nlm.nih.gov/28553933
https://pubmed.ncbi.nlm.nih.gov/28553933
Autor:
Navneet Ratti, Amanda Chargin, Bruce K. Patterson, Uma Sundram, Rian Morgan, Ellen L. Tsay, Keith Shults
Publikováno v:
Cancer immunology, immunotherapy : CII. 65(11)
We report a truly quantitative technology for PD-L1 expression in non-small cell lung cancer (NSCLC). In addition, we present a non-enzymatic technology that creates a cell suspension from fresh tumor tissue so that either fine-needle aspiration (FNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6349baaa402eceeda977040fd7e7d66b
https://pubmed.ncbi.nlm.nih.gov/27565980
https://pubmed.ncbi.nlm.nih.gov/27565980
Autor:
Amanda Chargin, Keith Shults, Uma Sundram, Rian Morgan, Navneet Ratti, Bruce K. Patterson, Ryan Rodriguez
Publikováno v:
Journal of Thoracic Oncology. 12:S545-S546
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adaf9b5002712ceeaad5d66b85da3caf
https://doi.org/10.1016/j.jtho.2016.11.677
https://doi.org/10.1016/j.jtho.2016.11.677
Autor:
Priya Gogoi, Will Chow, Kalyan Handique, Vishal Sharma, Bruce K. Patterson, Fariba Fazeli, Amanda Chargin
Publikováno v:
Cancer Research. 78:635-635
Detection of PD-L1 expression in NSCLC cancer patients is increasingly becoming a widely used molecular diagnostic tool. Evidence also suggests that PD-L1 can be induced with radiotherapy and may be an immune escape mechanism in cancer. Current metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92477bb56503417e1d245d4b51a1f38a
https://doi.org/10.1158/1538-7445.am2018-635
https://doi.org/10.1158/1538-7445.am2018-635
Publikováno v:
Journal of Clinical Oncology. 36:6064-6064
6064Background: Patients with Head and Neck Squamous Cell Carcinoma (HNSCC) have better prognosis when HPV associated or with a positive PD-L1 status. The often invasive nature of testing as well a...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b06620723c0561c3b7659f8fdb322680
https://doi.org/10.1200/jco.2018.36.15_suppl.6064
https://doi.org/10.1200/jco.2018.36.15_suppl.6064
Publikováno v:
Journal of Clinical Oncology. 36:114-114
114 Background: Research into causality of head and neck squamous cell carcinoma (HNSCC) has found a link to HPV infections affiliated with better survival than tobacco associated HNSCC. Currently, p16 immunohistochemistry is used as a predictive bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df802104885c10aa6e76236b6a1b06a6
https://doi.org/10.1200/jco.2018.36.5_suppl.114
https://doi.org/10.1200/jco.2018.36.5_suppl.114
Autor:
Bruce K. Patterson, Aaron Wagner, Stephen G. Young, Christen Griego-Fullbright, Amanda Chargin
Publikováno v:
Journal of Clinical Oncology. 36:159-159
159 Background: Tumor cell expression of PD-L1 leads to the inhibition of immune responses specifically inactivation of cytotoxic T-cells. PD-L1 expression on tumor cells by immunohistochemistry does not provide the complete picture of therapeutic (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::585da8eea08d972ed68eb764a326ab98
https://doi.org/10.1200/jco.2018.36.5_suppl.159
https://doi.org/10.1200/jco.2018.36.5_suppl.159
Publikováno v:
Clinical Cancer Research. 23:49-49
Background: Human papillomaviruses are a family of DNA viruses that infect the epithelium leading to the formation of lesions with the ability to progress into carcinoma in many forms. Research into causality of head and neck cancers has found a link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f532993ee758eebffe99b30c68d36613
https://doi.org/10.1158/1557-3265.aacrahns17-49
https://doi.org/10.1158/1557-3265.aacrahns17-49