Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Amanda Castellano"'
Autor:
Leslie W Tari, Xiaoming Li, Michael Trzoss, Daniel C Bensen, Zhiyong Chen, Thanh Lam, Junhu Zhang, Suk Joong Lee, Grayson Hough, Doug Phillipson, Suzanne Akers-Rodriguez, Mark L Cunningham, Bryan P Kwan, Kirk J Nelson, Amanda Castellano, Jeff B Locke, Vickie Brown-Driver, Timothy M Murphy, Voon S Ong, Chris M Pillar, Dean L Shinabarger, Jay Nix, Felice C Lightstone, Sergio E Wong, Toan B Nguyen, Karen J Shaw, John Finn
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84409 (2013)
Increasing resistance to every major class of antibiotics and a dearth of novel classes of antibacterial agents in development pipelines has created a dwindling reservoir of treatment options for serious bacterial infections. The bacterial type IIA t
Externí odkaz:
https://doaj.org/article/61b9ed4eb647499192d901bd0163432e
Autor:
Mark L. Cunningham, Doug Phillipson, Bryan P. Kwan, John T. Finn, Kirk J. Nelson, Sergio E. Wong, Michael Trzoss, Jeff B. Locke, Jay C. Nix, Vickie Brown-Driver, Felice C. Lightstone, Zhiyong Chen, Toan B. Nguyen, Karen J. Shaw, Suzanne Akers-Rodriguez, Xiaoming Li, Suk Joong Lee, Amanda Castellano, Dean L. Shinabarger, Timothy M. Murphy, Junhu Zhang, Leslie W. Tari, Chris M. Pillar, Voon Ong, Grayson Hough, Thanh Lam, Daniel C. Bensen
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84409 (2013)
PLoS ONE
PLoS ONE
Increasing resistance to every major class of antibiotics and a dearth of novel classes of antibacterial agents in development pipelines has created a dwindling reservoir of treatment options for serious bacterial infections. The bacterial type IIA t
Autor:
Vickie Brown-Driver, Christopher J. Creighton, John T. Finn, Toan B. Nguyen, Mark L. Cunningham, Zhiyong Chen, Amanda Castellano, Mark Stidham, Sergio E. Wong, Xiaoming Li, Karen J. Shaw, Thanh Lam, Junhu Zhang, Bryan P. Kwan, Kirk J. Nelson, Felice C. Lightstone, Leslie W. Tari, Daniel C. Bensen, Micheal Trzoss
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(5)
The structurally related bacterial topoisomerases DNA gyrase (GyrB) and topoisomerase IV (ParE) have long been recognized as prime candidates for the development of broad spectrum antibacterial agents. However, GyrB/ParE targeting antibacterials with