Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Amanda C. Martyn"'
Autor:
Flavio H. Beraldo, Anu Thomas, Benjamin Kolisnyk, Pedro H. Hirata, Xavier De Jaeger, Amanda C. Martyn, Jue Fan, Daniela F. Goncalves, Matthew F. Cowan, Talal Masood, Vilma R. Martins, Robert Gros, Vania F. Prado, Marco A. M. Prado
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 11, Pp 1457-1466 (2015)
Stress-inducible phosphoprotein I (STIP1, STI1 or HOP) is a co-chaperone intermediating Hsp70/Hsp90 exchange of client proteins, but it can also be secreted to trigger prion protein-mediated neuronal signaling. Some mothers of children with autism sp
Externí odkaz:
https://doaj.org/article/d92dfd7a39ac4bbfa533c0c083604adc
Autor:
Amanda C Martyn, Krisztian Toth, Robert Schmalzigaug, Nathan G Hedrick, Ramona M Rodriguiz, Ryohei Yasuda, William C Wetsel, Richard T Premont
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194350 (2018)
The signaling scaffold protein GIT1 is expressed widely throughout the brain, but its function in vivo remains elusive. Mice lacking GIT1 have been proposed as a model for attention deficit-hyperactivity disorder, due to alterations in basal locomoto
Externí odkaz:
https://doaj.org/article/40a0aacba1ec4d478275acafdc3fda0d
Autor:
Richard T. Premont, Bastrikova N, Robert Schmalzigaug, William C. Wetsel, Ahmed U, Kim W, Ramona M. Rodriguiz, Krisztián Tóth, Amanda C. Martyn, Serena M. Dudek
G protein-coupled receptor kinase-interacting protein 2 (GIT2) and GIT1 are highly similar, sharing the same domain structure and many binding partners. The most important GIT partners are the p21-activated protein kinase-interacting exchange factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23e77a8b58c81d889fd4864f076b2d6
https://doi.org/10.1101/538223
https://doi.org/10.1101/538223
Autor:
Robert Schmalzigaug, Ryohei Yasuda, Richard T. Premont, Amanda C. Martyn, William C. Wetsel, Krisztián Tóth, Nathan G. Hedrick, Ramona M. Rodriguiz
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0194350 (2018)
PLoS ONE, Vol 13, Iss 3, p e0194350 (2018)
The signaling scaffold protein GIT1 is expressed widely throughout the brain, but its function in vivo remains elusive. Mice lacking GIT1 have been proposed as a model for attention deficit-hyperactivity disorder, due to alterations in basal locomoto
Autor:
Genqing Liang, Elena Choleris, Kimberly Cai, Patricia V. Turner, Ray Lu, Amanda C. Martyn, Daniel Gillis, John N. Armstrong, Talya R. Amor, Adam R. R. McCluggage
Publikováno v:
Molecular and Cellular Biology. 32:5140-5150
The hypothalamic-pituitary-adrenal (HPA) axis is a major part of the neuroendocrine system in animal responses to stress. It is known that the HPA axis is attenuated at parturition to prevent detrimental effects of glucocorticoid secretion including
Autor:
Daniela F. Goncalves, Rohit Kesarwani, John F. MacDonald, Marco A. M. Prado, Michael F. Jackson, Xavier De Jaeger, Sanda Raulic, Amanda C. Martyn, Ivan Izquierdo, Vania F. Prado, Ana C. Magalhães, Monica S. Guzman
Publikováno v:
Anatomy and Cell Biology Publications
Basal forebrain cholinergic neurons, which innervate the hippocampus and cortex, have been implicated in many forms of cognitive function. Immunolesion-based methods in animal models have been widely used to study the role of acetylcholine (ACh) neur
Autor:
Flavio H. Beraldo, Michael F. Jackson, Marco A. M. Prado, John F. MacDonald, Jue Fan, Jillian C. Belrose, Monica S. Guzman, Valeriy G. Ostapchenko, Vania F. Prado, Yasuo Mori, Amanda C. Martyn, Natalie Lavine, Megan Chen, Yu-Feng Xie
Publikováno v:
Anatomy and Cell Biology Publications
In Alzheimer's disease, accumulation of soluble oligomers of β-amyloid peptide is known to be highly toxic, causing disturbances in synaptic activity and neuronal death. Multiple studies relate these effects to increased oxidative stress and aberran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0d1d0893f2f6e438318d10d3ec5092
https://ir.lib.uwo.ca/context/anatomypub/article/1082/viewcontent/15157.full.pdf
https://ir.lib.uwo.ca/context/anatomypub/article/1082/viewcontent/15157.full.pdf
Publikováno v:
Biochemical and Biophysical Research Communications. 391:1352-1357
CREBZF (also called ZF or Zhangfei) is a basic region-leucine zipper transcription factor that has been implicated in the herpesvirus infection cycle and related cellular processes. Since ATF4 is known to play a key role in cellular responses to vari
Autor:
Anson K. C. Li, Ian S. McDonald, Amanda C. Martyn, Vania F. Prado, Eric A. Dolinar, Kathleen A. Hill, Stuart G Coupland, Jake Bedore, Marco A. M. Prado
Publikováno v:
Anatomy and Cell Biology Publications
PLoS ONE
PLoS ONE, Vol 10, Iss 7, p e0133989 (2015)
PLoS ONE
PLoS ONE, Vol 10, Iss 7, p e0133989 (2015)
Background Despite rigorous characterization of the role of acetylcholine in retinal development, long-term effects of its absence as a neurotransmitter are unknown. One of the unanswered questions is how acetylcholine contributes to the functional c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039c18302401d7eda455eec397846708
https://ir.lib.uwo.ca/anatomypub/86
https://ir.lib.uwo.ca/anatomypub/86
Autor:
Amanda C. Martyn, Robert Gros, Vilma R. Martins, Pedro H. Hirata, Jue Fan, Vania F. Prado, Talal S. Masood, Anu Alice Thomas, Daniela F. Goncalves, Matthew F. Cowan, Benjamin Kolisnyk, Xavier De Jaeger, Flavio H. Beraldo, Marco A. M. Prado
Publikováno v:
Anatomy and Cell Biology Publications
Disease Models & Mechanisms, Vol 8, Iss 11, Pp 1457-1466 (2015)
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 8, Iss 11, Pp 1457-1466 (2015)
Disease Models & Mechanisms
Stress-inducible phosphoprotein I (STIP1, STI1 or HOP) is a co-chaperone intermediating Hsp70/Hsp90 exchange of client proteins, but it can also be secreted to trigger prion protein-mediated neuronal signaling. Some mothers of children with autism sp