Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Amanda C, Barber"'
Autor:
Bart Nieuwenhuis, Amanda C Barber, Rachel S Evans, Craig S Pearson, Joachim Fuchs, Amy R MacQueen, Susan vanErp, Barbara Haenzi, Lianne A Hulshof, Andrew Osborne, Raquel Conceicao, Tasneem Z Khatib, Sarita S Deshpande, Joshua Cave, Charles Ffrench‐Constant, Patrice D Smith, Klaus Okkenhaug, Britta J Eickholt, Keith R Martin, James W Fawcett, Richard Eva
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
Abstract Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regenerati
Externí odkaz:
https://doaj.org/article/774319b15576431a80d815b1901eaee3
Autor:
Paul V. Waldron, Fabiana Di Marco, Kamil Kruczek, Joana Ribeiro, Anna B. Graca, Claire Hippert, Nozie D. Aghaizu, Aikaterini A. Kalargyrou, Amanda C. Barber, Giulia Grimaldi, Yanai Duran, Samuel J.I. Blackford, Magdalena Kloc, Debbie Goh, Eduardo Zabala Aldunate, Robert D. Sampson, James W.B. Bainbridge, Alexander J. Smith, Anai Gonzalez-Cordero, Jane C. Sowden, Robin R. Ali, Rachael A. Pearson
Publikováno v:
Stem Cell Reports, Vol 10, Iss 2, Pp 406-421 (2018)
Summary: Human vision relies heavily upon cone photoreceptors, and their loss results in permanent visual impairment. Transplantation of healthy photoreceptors can restore visual function in models of inherited blindness, a process previously underst
Externí odkaz:
https://doaj.org/article/9c09c8d9a3254109b4487e9be40e1549
Publikováno v:
eLife, Vol 7 (2018)
The failure of mammalian CNS neurons to regenerate their axons derives from a combination of intrinsic deficits and extrinsic factors. Following injury, chondroitin sulfate proteoglycans (CSPGs) within the glial scar inhibit axonal regeneration, an a
Externí odkaz:
https://doaj.org/article/2a2686f1f6e14bd8afebce939fc83fc9
Autor:
Claire Hippert, Anna B Graca, Amanda C Barber, Emma L West, Alexander J Smith, Robin R Ali, Rachael A Pearson
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120415 (2015)
Despite different aetiologies, most inherited retinal disorders culminate in photoreceptor loss, which induces concomitant changes in the neural retina, one of the most striking being reactive gliosis by Müller cells. It is typically assumed that ph
Externí odkaz:
https://doaj.org/article/846fedb3d31e4aa59f20d7769288772b
Autor:
Charles ffrench-Constant, Craig S Pearson, Amanda C. Barber, Keith R Martin, Bart Nieuwenhuis, Tasneem Z Khatib, Patrice D. Smith, Rachel S Evans, Lianne A Hulshof, Joachim Fuchs, Richard Eva, Klaus Okkenhaug, Raquel D. Conceição, Sarita S Deshpande, Britta J. Eickholt, Andrew Osborne, Joshua Cave, James W. Fawcett, Barbara Haenzi, Susan van Erp, Amy R. MacQueen
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
Nieuwenhuis, B, Barber, A C, Evans, R S, Pearson, C S, Fuchs, J, MacQueen, A R, van Erp, S, Haenzi, B, Hulshof, L A, Osborne, A, Conceicao, R, Khatib, T Z, Deshpande, S S, Cave, J, Ffrench-Constant, C, Smith, P D, Okkenhaug, K, Eickholt, B J, Martin, K R, Fawcett, J W & Eva, R 2020, ' PI 3-kinase delta enhances axonal PIP 3 to support axon regeneration in the adult CNS ', EMBO Molecular Medicine, vol. 12, no. 8, e11674 . https://doi.org/10.15252/emmm.201911674
EMBO Molecular Medicine, 12. Wiley-Blackwell
Nieuwenhuis, B, Barber, A C, Evans, R S, Pearson, C S, Fuchs, J, MacQueen, A R, van Erp, S, Haenzi, B, Hulshof, L A, Osborne, A, Conceicao, R, Khatib, T Z, Deshpande, S S, Cave, J, Ffrench-Constant, C, Smith, P D, Okkenhaug, K, Eickholt, B J, Martin, K R, Fawcett, J W & Eva, R 2020, ' PI 3-kinase delta enhances axonal PIP 3 to support axon regeneration in the adult CNS ', EMBO Molecular Medicine, vol. 12, no. 8, e11674 . https://doi.org/10.15252/emmm.201911674
EMBO Molecular Medicine, 12. Wiley-Blackwell
Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regeneration, we fo
Autor:
Bart, Nieuwenhuis, Amanda C, Barber, Rachel S, Evans, Craig S, Pearson, Joachim, Fuchs, Amy R, MacQueen, Susan, van Erp, Barbara, Haenzi, Lianne A, Hulshof, Andrew, Osborne, Raquel, Conceicao, Tasneem Z, Khatib, Sarita S, Deshpande, Joshua, Cave, Charles, Ffrench-Constant, Patrice D, Smith, Klaus, Okkenhaug, Britta J, Eickholt, Keith R, Martin, James W, Fawcett, Richard, Eva
Publikováno v:
EMBO Molecular Medicine
Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regeneration, we fo
Autor:
Sarita S Deshpande, Andrew Osborne, Keith R Martin, Barbara Hänzi, Amanda C. Barber, Raquel D. Conceição, Rachel S Evans, Craig S Pearson
Publikováno v:
Investigative Ophthalmology & Visual Science
Funder: Wellcome Trust
PURPOSE: Regeneration of optic nerve axons after injury can be facilitated by several approaches, but misguidance at the optic chiasm is often observed. We characterized guidance cues in the embryonic visual system and adu
PURPOSE: Regeneration of optic nerve axons after injury can be facilitated by several approaches, but misguidance at the optic chiasm is often observed. We characterized guidance cues in the embryonic visual system and adu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1bbcfd0ce9a591b49427d2d366e2a1
https://www.repository.cam.ac.uk/handle/1810/299999
https://www.repository.cam.ac.uk/handle/1810/299999
Autor:
Joachim Fuchs, Raquel D. Conceição, Bart Nieuwenhuis, Barabara Haenzi, James W. Fawcett, Charles ffrench-Constant, Klaus Okkenhaug, Patrice D. Smith, Susan van Erp, Richard Eva, Keith R Martin, Britta J. Eickholt, Andrew Osborne, Craig S Pearson, Rachel S Evans, Amy R. MacQueen, Amanda C. Barber, Sarita S Deshpande, Joshua Cave, Lianne A Hulshof
Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regeneration, we fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3489aa2318f5f2428a7995198533cf1b
https://doi.org/10.1101/787994
https://doi.org/10.1101/787994
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
The failure of mammalian CNS neurons to regenerate their axons derives from a combination of intrinsic deficits and extrinsic factors. Following injury, chondroitin sulfate proteoglycans (CSPGs) within the glial scar inhibit axonal regeneration, an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc0859b2a94c6f8869b0f50aa55d916
https://www.repository.cam.ac.uk/handle/1810/280569
https://www.repository.cam.ac.uk/handle/1810/280569