Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Amanda Balesano"'
Autor:
Angela C. Doran, Alyssa L. Dantonio, Gabrielle M. Gualtieri, Amanda Balesano, Connor Landers, Woodrow Burchett, Theunis C. Goosen, R. Scott Obach
Publikováno v:
Drug Metabolism and Disposition. 50:1272-1286
Cytochrome P450 reaction phenotyping to determine the fraction of metabolism values (f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d75f4c59170879ccb0e19a61073e75
https://doi.org/10.1124/dmd.122.000883
https://doi.org/10.1124/dmd.122.000883
Autor:
Angela C. Doran, Woodrow Burchett, Connor Landers, Gabrielle M. Gualtieri, Amanda Balesano, Heather Eng, Alyssa L Dantonio, Theunis C. Goosen, R. Scott Obach
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals.
The utility of chemical inhibitors in cytochrome P450 (CYP) reaction phenotyping is highly dependent on their selectivity and potency for their target CYP isoforms. In the present study, seventeen inhibitors of CYP1A2, 2B6, 2C8, 2C9, 2C19, 2D6, and 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85fdb54fca7319cb247bf9771b45d19f
https://pubmed.ncbi.nlm.nih.gov/35777846
https://pubmed.ncbi.nlm.nih.gov/35777846
Publikováno v:
The AAPS Journal. 23
Alcohol dehydrogenases (ADHs) are most known for their roles in oxidation and elimination of ethanol. Although less known, ADHs also play a critical role in the metabolism of a number of drugs and metabolites that contain alcohol functional groups, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f64199a47f8654a5050c523d75b424b
https://doi.org/10.1208/s12248-020-00536-y
https://doi.org/10.1208/s12248-020-00536-y