Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Amanda Baer"'
Autor:
Marina Cuchel, Anna C. Raper, Donna M. Conlon, Daniel A. Pryma, Richard H. Freifelder, Rahul Poria, Debra Cromley, Xiaoyu Li, Richard L. Dunbar, Benjamin French, Liming Qu, William Farver, Ching-Chiang Su, Sissel Lund-Katz, Amanda Baer, Giacomo Ruotolo, Peter Akerblad, Carol S. Ryan, Lan Xiao, Todd G. Kirchgessner, John S. Millar, Jeffrey T. Billheimer, Daniel J. Rader
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 4, Pp 752-762 (2017)
Reverse cholesterol transport (RCT) is thought to be an atheroprotective function of HDL, and macrophage-specific RCT in mice is inversely associated with atherosclerosis. We developed a novel method using 3H-cholesterol nanoparticles to selectively
Externí odkaz:
https://doaj.org/article/50852041bbb149b0ab71cadc9ddee278
Autor:
Michael E. Lassman, Wahida Karmally, John A. Wagner, Patricia Jumes, Amanda Baer, Gissette Reyes-Soffer, John S. Millar, Soumia Aoujil, David E. Gutstein, Yang Liu, Emile M. deGoma, Richard L. Dunbar, Daniel J. Rader, Stephen Holleran, Hashmi Rafeek, Tiffany Thomas, Rajasekhar Ramakrishnan, Daniel S. Donovan, Henry N. Ginsberg, Taylor Standiford, Joseph C. Obunike
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1214-1220 (2017)
Cholesteryl ester transfer protein (CETP) mediates the transfer of HDL cholesteryl esters for triglyceride (TG) in VLDL/LDL. CETP inhibition, with anacetrapib, increases HDL-cholesterol, reduces LDL-cholesterol, and lowers TG levels. This study descr
Autor:
Richard L. Dunbar, Todd G. Kirchgessner, Rahul Poria, Donna M. Conlon, Debra Cromley, Carol S. Ryan, Marina Cuchel, Amanda Baer, Jeffrey T. Billheimer, Daniel J. Rader, Sissel Lund-Katz, Richard Freifelder, Liming Qu, Anna Raper, Giancomo Ruotolo, John S. Millar, Ching-Chiang Su, Peter Åkerblad, Benjamin French, Xiaoyu Li, William Farver, Daniel A. Pryma, Lan Xiao
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 4, Pp 752-762 (2017)
Reverse cholesterol transport (RCT) is thought to be an atheroprotective function of HDL, and macrophage-specific RCT in mice is inversely associated with atherosclerosis. We developed a novel method using 3H-cholesterol nanoparticles to selectively
Autor:
Patricia Jumes, Rajasekhar Ramakrishnan, Stephen Holleran, John S. Millar, Gissette Reyes-Soffer, Amanda Baer, Yang Liu, Henry N. Ginsberg, Tiffany Thomas, David E. Gutstein, John A. Wagner, Amy O. Johnson-Levonas, Richard L. Dunbar, Emil M. deGoma, Daniel J. Rader, Michael E. Lassman, Wahida Karmally, Colleen Ngai, Ellie Coromilas, Hashmi Rafeek, Daniel S. Donovan, Bela F. Asztalos
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36:994-1002
Objective— Anacetrapib (ANA), an inhibitor of cholesteryl ester transfer protein (CETP) activity, increases plasma concentrations of high-density lipoprotein cholesterol (HDL-C), apolipoprotein A-I (apoA)-I, apoA-II, and CETP. The mechanisms respon
Publikováno v:
Clinical and Translational Science. 3:140-146
The benefit in reducing cardiovascular risk with statins has been attributed both to cholesterol lowering and pleiotropic effects. These pleiotropic effects are thought to include attenuation of the inflammatory response due to reduced prenylation of
Autor:
Hashmi Rafeek, Amy O. Johnson-Levonas, Richard L. Dunbar, Laura Pollan, David E. Gutstein, Emil M. deGoma, John A. Wagner, Rajasekhar Ramakrishnan, Stephen Holleran, Amanda Baer, Wahida Karmally, Junichiro Tohyama, Gissette Reyes-Soffer, Daniel J. Rader, Daniel S. Donovan, Henry N. Ginsberg, Michael E. Lassman, Joseph C. Obunike, John S. Millar, Patricia Jumes, Yang Liu
Individuals treated with the cholesteryl ester transfer protein (CETP) inhibitor anacetrapib exhibit a reduction in both LDL cholesterol and apolipoprotein B (ApoB) in response to monotherapy or combination therapy with a statin. It is not clear how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0694afdf63c765fb43ca62003be43db
https://europepmc.org/articles/PMC4497759/
https://europepmc.org/articles/PMC4497759/
Autor:
Daniel M. Kolansky, Bruce S. Sachais, Anna Raper, Amanda Baer, Emma A. Meagher, Marina Cuchel
We report the case of a 49-year-old woman with homozygous familial hypercholesterolemia and a complicated cardiovascular history, treated for 5 years with a microsomal triglyceride transfer protein inhibitor in addition to her other lipid-lowering th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f7f63e0921b929b6530265194d5acb
https://europepmc.org/articles/PMC4563802/
https://europepmc.org/articles/PMC4563802/
Autor:
Richard L Dunbar, Marina Cuchel, John S Millar, Amanda Baer, Rahul Poria, Richard H Freifelder, Daniel A Pryma, Jeffrey J Billheimer, Daniel J Rader
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33
Background HDL may be atheroprotective by accelerating reverse cholesterol transport (RCT). Niacin raises HDL cholesterol (HDL-c) and niacin monotherapy up to 3g/d prevented coronary events, possibly by accelerating RCT. However, up to 2g/d niacin di
Autor:
Yiding, Yu, Nikhil, Sheth, Parasuram, Krishnamoorthy, Babak, Saboury, Anna, Raper, Amanda, Baer, Rachel, Ochotony, Julia, Doveikis, Stephanie, Derohannessian, Abby S Van, Voorhees, Drew A, Torigian, Abass, Alavi, Joel M, Gelfand, Nehal N, Mehta
Publikováno v:
American journal of cardiovascular disease. 2(4)
Psoriasis is a model Th1-mediated inflammatory disease associated with increased incidence of stroke and cardiovascular disease (CVD). The mechanism behind these associations is unknown, however abnormal HDL particle composition measured by nuclear m
Autor:
YiDing Yu, Parasuram Krishnamoorthy, Anna Raper, Ron C. Li, Joel M. Gelfand, Daniel J. Rader, Stephanie DerOhannesian, Amrith Rodrigues, Amanda Baer, Nehal N. Mehta, William Farver, Mackenzie Wilcox, Muredach P. Reilly, Megan L. Wolfe, Abby VanVoorhees
Publikováno v:
Atherosclerosis. 224(1)
Psoriasis is a Th-1/17 mediated inflammatory disease associated with increased risk of cardiovascular disease (CVD). Inflammation may modulate lipoprotein particle number and directly impair HDL functions, in particular reverse cholesterol transport