Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Amanda B. Parris"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Metformin shows promise in breast cancer prevention, but its underlying mechanisms remain unclear. This study investigated the impact of metformin on the repopulation dynamics of mammary epithelial cells (MECs) and the signaling pathways in non-tumor
Externí odkaz:
https://doaj.org/article/8f6cdf42f98b410f88f584c1a4336ebf
Autor:
Harry Lee, Nipun Saini, Erin W. Howard, Amanda B. Parris, Zhikun Ma, Qingxia Zhao, Ming Zhao, Bolin Liu, Susan M. Edgerton, Ann D. Thor, Xiaohe Yang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Although ErbB2-targeted therapeutics have significantly improved ErbB2+ breast cancer patient outcomes, therapeutic resistance remains a significant challenge. Therefore, the development of novel ErbB2-targeting strategies is necessary. Impo
Externí odkaz:
https://doaj.org/article/1473348218e04bcdaf8b1ef3f2493fea
Publikováno v:
Cells, Vol 10, Iss 11, p 3008 (2021)
Resistance to CDK4/6 inhibitors (CDKis) is emerging as a clinical challenge. Identification of the factors contributing to CDKi resistance, with mechanistic insight, is of pivotal significance. Recent studies linked aberrant FGFR signaling to CDKi re
Externí odkaz:
https://doaj.org/article/38f749d3ca5843bd8db0c6c7fa6acc84
Autor:
Zhikun Ma, Amanda B. Parris, Erin W. Howard, Meghan Davis, Xia Cao, Courtney Woods, Xiaohe Yang
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3095 (2020)
Bisphenol A (BPA) is the most common environmental endocrine disrupting chemical. Studies suggest a link between perinatal BPA exposure and increased breast cancer risk, but the underlying mechanisms remain unclear. This study aims to investigate the
Externí odkaz:
https://doaj.org/article/3f2f9d1ef6964f66b01ebedac76c6994
Publikováno v:
Cancer Research. 82:1123-1123
Triple negative breast cancer (TNBC) is the breast cancer subtype that is most refractory to treatment. Thus, identification of novel molecular targets and drug treatments are needed to improve prognosis for patients. The widely used anti-diabetic dr
Autor:
Qingxia Zhao, Nipun Saini, Ann D. Thor, Harry Lee, Zhikun Ma, Xiaohe Yang, Bolin Liu, Erin W. Howard, Susan M. Edgerton, Amanda B. Parris, Ming Zhao
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
Although ErbB2-targeted therapeutics have significantly improved ErbB2+ breast cancer patient outcomes, therapeutic resistance remains a significant challenge. Therefore, the development of novel ErbB2-targeting strategies is necessary. Importantly,
Autor:
Zhikun Ma, Amanda B. Parris, Erin W. Howard, Xiaohe Yang, Qingxia Zhao, Zhiying Guo, Ming Zhao
Publikováno v:
Oncotarget
// Zhiying Guo 1 , Ming Zhao 1 , Erin W. Howard 1 , Qingxia Zhao 1 , Amanda B. Parris 1 , Zhikun Ma 1 and Xiaohe Yang 1 1 Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina
Autor:
Erin W. Howard, Ming Zhao, Zhiying Guo, Zhikun Ma, Qingxia Zhao, Amanda B. Parris, Susan M. Edgerton, Bolin Liu, Ann D. Thor, Ying Xing, Xiaohe Yang
Publikováno v:
Oncotarget
// Ming Zhao 1 , Erin W. Howard 1 , Amanda B. Parris 1 , Zhiying Guo 1 , Qingxia Zhao 1, 2 , Zhikun Ma 1 , Ying Xing 2 , Bolin Liu 3 , Susan M. Edgerton 3 , Ann D. Thor 3 and Xiaohe Yang 1, 4 1 Julius L. Chambers Biomedical/Biotechnology Research Ins
Publikováno v:
International Journal of Oncology
Heat shock protein 90 (HSP90) regulates several important cellular processes via its repertoire of 'client proteins'. These client proteins have been found to play fundamental roles in signal transduction, cell proliferation, cell cycle progression a
Autor:
Zengjun Wang, James L. Mohler, Amanda B. Parris, Shifeng Su, Elizabeth M. Wilson, Gail Grossman
Publikováno v:
The Prostate. 77:505-516
BACKGROUND High affinity androgen binding to the androgen receptor (AR) activates genes required for male sex differentiation and promotes the development and progression of prostate cancer. Human AR transcriptional activity involves interactions wit