Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Amanda B. Macedo"'
Autor:
Indra Sarabia, Camille L. Novis, Amanda B. Macedo, Hiroshi Takata, Racheal Nell, Juyeon C. Kakazu, Robert L. Furler, Binita Shakya, Heidi L. Schubert, Christopher P. Hill, Ana Beatriz DePaula-Silva, Adam M. Spivak, Lydie Trautmann, Vicente Planelles, Alberto Bosque
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The mitochondrial antiviral signaling protein (MAVS) is part of the cell’s innate immune mechanism of defense. MAVS mRNA is bicistronic and can give rise to a full length-MAVS and a shorter isoform termed miniMAVS. In response to viral infections,
Externí odkaz:
https://doaj.org/article/2d9d89e2d68d41a7894a9b45ae46dc68
Autor:
Alberto Bosque, Kyle A. Nilson, Amanda B. Macedo, Adam M. Spivak, Nancie M. Archin, Ryan M. Van Wagoner, Laura J. Martins, Camille L. Novis, Matthew A. Szaniawski, Chris M. Ireland, David M. Margolis, David H. Price, Vicente Planelles
Publikováno v:
Cell Reports, Vol 18, Iss 5, Pp 1324-1334 (2017)
The presence of latent HIV-1 in infected individuals represents a major barrier preventing viral eradication. For that reason, reactivation of latent viruses in the presence of antiretroviral regimens has been proposed as a therapeutic strategy to ac
Externí odkaz:
https://doaj.org/article/92f594697d114cf5b8096f3da8d8641c
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The elimination of both cellular and tissue latent reservoirs is a challenge toward a successful HIV cure. “Shock and Kill” are among the therapeutic strategies that have been more extensively studied to target these reservoirs. These strategies
Externí odkaz:
https://doaj.org/article/bd125428e6ee4ca481a2e1eeb4d917a6
Autor:
Erica C Larson, Camille L Novis, Laura J Martins, Amanda B Macedo, Kadyn E Kimball, Alberto Bosque, Vicente Planelles, Louis R Barrows
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185162 (2017)
Following proviral integration into the host cell genome and establishment of a latent state, the human immunodeficiency virus type 1 (HIV-1) can reenter a productive life cycle in response to various stimuli. HIV-1 reactivation occurs when transcrip
Externí odkaz:
https://doaj.org/article/a2e8dc7a41ce4fd4a5543da80b0e0f14
Autor:
Amanda B. Macedo, Callie Levinger, Bryan N. Nguyen, Jonathan Richard, Mamta Gupta, Conrad Russell Y. Cruz, Andrés Finzi, Katherine B. Chiappinelli, Keith A. Crandall, Alberto Bosque
Publikováno v:
Journal of virology. 96(15)
Elimination of human immunodeficiency virus (HIV) reservoirs is a critical endpoint to eradicate HIV. One therapeutic intervention against latent HIV is “shock and kill.” This strategy is based on the transcriptional activation of latent HIV with
Autor:
Catherine M. Bollard, Yanqin Ren, Amanda B. Macedo, Avery Wimpelberg, Thomas Rohwetter, Szu-Han Huang, Dean Magat, Ryan Durga, W. David Hardy, Elizabeth Zale, Shabnum Patel, Alberto Bosque, R. Brad Jones, Dughan J. Ahimovic, Erika Benko, Colin Kovacs, Talia M. Mota, Chase D. McCann, Winiffer D. Conce Alberto, Dora Chan, Christopher Cannon, Ronald Truong
Publikováno v:
J Clin Invest
Curing HIV infection will require the elimination of a reservoir of infected CD4(+) T cells that persists despite HIV-specific cytotoxic T cell (CTL) responses. Although viral latency is a critical factor in this persistence, recent evidence also sug
Autor:
Callie Levinger, Katherine B. Chiappinelli, Bryan N. Nguyen, Mampta Gupta, Alberto Bosque, Conrad Russell Y. Cruz, Keith A. Crandall, Amanda B. Macedo
Elimination of latent HIV reservoirs is a critical endpoint to eradicate HIV. One therapeutic intervention against latent HIV is ‘shock and kill’. This strategy is based on the transcriptional activation of latent HIV with a Latency-Reversing Age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbe2d00eeb4927c7a6f8a2f6c525ffe4
https://doi.org/10.1101/2021.10.14.464348
https://doi.org/10.1101/2021.10.14.464348
Autor:
Erika Benko, Colin Kovacs, Dora Chan, Alberto Bosque, Szu-Han Huang, R. Brad Jones, Adam R. Ward, Paul Zumbo, Dennis C Copertino, Friederike Dündar, Talia M. Mota, Ronald Truong, Winiffer D. Conce Alberto, Louise Leyre, Thais Klevorn, Yanqin Ren, Amanda B. Macedo, Thomas Rohwetter, Doron Betel
Publikováno v:
Journal of Virology. 95
HIV persists, despite immune responses and antiretroviral therapy, in viral reservoirs that seed rebound viremia if therapy is interrupted. Previously, we showed that the BCL-2 protein contributes to HIV persistence by conferring a survival advantage
Autor:
Yanqin, Ren, Szu Han, Huang, Amanda B, Macedo, Adam R, Ward, Winiffer D Conce, Alberto, Thais, Klevorn, Louise, Leyre, Dennis C, Copertino, Talia M, Mota, Dora, Chan, Ronald, Truong, Thomas, Rohwetter, Paul, Zumbo, Friederike, Dündar, Doron, Betel, Colin, Kovacs, Erika, Benko, Alberto, Bosque, R Brad, Jones
Publikováno v:
J Virol
HIV persists, despite immune responses and antiretroviral therapy, in viral reservoirs that seed rebound viremia if therapy is interrupted. Previously, we showed that the BCL-2 protein contributes to HIV persistence by conferring a survival advantage
Autor:
Amanda B. Macedo, Juyeon C. Kakazu, Camille L. Novis, Binita Shakya, Robert L. Furler, Vicente Planelles, Heidi L. Schubert, Lydie Trautmann, Adam M. Spivak, Racheal A. Nell, Alberto Bosque, Hiroshi Takata, Ana Beatriz DePaula-Silva, Indra Sarabia, Christopher P. Hill
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
The mitochondrial antiviral signaling protein (MAVS) is part of the cell’s innate immune mechanism of defense. MAVS mRNA is bicistronic and can give rise to a full length-MAVS and a shorter isoform termed miniMAVS. In response to viral infections,