Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Amanda Allan"'
Autor:
Giulietta Maria Riboldi, Ricardo A. Vialle, Elisa Navarro, Evan Udine, Katia de Paiva Lopes, Jack Humphrey, Amanda Allan, Madison Parks, Brooklyn Henderson, Kelly Astudillo, Charalambos Argyrou, Maojuan Zhuang, Tamjeed Sikder, J. Oriol Narcis, Shilpa Dilip Kumar, William Janssen, Allison Sowa, Giacomo P. Comi, Alessio Di Fonzo, John F. Crary, Steven J. Frucht, Towfique Raj
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-17 (2022)
Abstract Background Genetic mutations in beta-glucocerebrosidase (GBA) represent the major genetic risk factor for Parkinson’s disease (PD). GBA participates in both the endo-lysosomal pathway and the immune response, two important mechanisms invol
Externí odkaz:
https://doaj.org/article/dbe17cf7cdea4ab8b6a5e2418d509f7c
Autor:
Maojuan Zhuang, Evan Udine, Roberto A. Ortega, Susan Bressman, Madison Parks, Deborah Raymond, Ritesh A. Ramdhani, Vicki Shanker, Katia de Paiva Lopes, Michael J. Chao, John F. Crary, Steven J. Frucht, Lotje de Witte, Gijsje J. L. J. Snijders, Matthew Swan, Towfique Raj, Elisa Navarro, Ruth H. Walker, Ana C. Pereira, Amanda Allan, Tim Ahfeldt, Jack Humphrey, Charalambos Argyrou, Sarah Simon, Winona Tse, Brooklyn Henderson, Sonya Elango, Rachel Saunders-Pullman, Alison Goate, Tamjeed Sikder, Brian M. Schilder, Carolyn W. Zhu, Ricardo Assunção Vialle, Kurt Farrell, Giulietta Riboldi, Mary Sano
Publikováno v:
Nat Aging
An increasing number of identified Parkinson’s disease (PD) risk loci contain genes highly expressed in innate immune cells, yet their role in pathology is not understood. We hypothesized that PD susceptibility genes modulate disease risk by influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d845e51929d5090dc55c3a4d9a4361
https://doi.org/10.1038/s43587-021-00110-x
https://doi.org/10.1038/s43587-021-00110-x
Autor:
Giulietta Maria Riboldi, Ricardo A Vialle, Elisa Navarro, Evan Udine, Katia de Paiva Lopes, Amanda Allan, Madison Parks, Brooklyn Henderson, Kelly Astudillo, Charalambos Argyrou, Maojuan Zhuang, Tamjeed Sikder, Oriol J. Narcis, Shilpa Dilip Kumar, William Janssen, Allison Sowa, Giacomo P Comi, Alessio Di Fonzo, John F. Crary, Steven J Frucht, Towfique Raj
BackgroundGenetic mutations in the beta-glucocerebrosidase (GCase), GBA gene, represent the major genetic risk factor for Parkinson’s disease (PD). The function of the GBA gene is at the crossroads between the endo-lysosomal pathway and the immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8f6d03fb7658e6d0e9b62e356d87686
https://doi.org/10.1101/2021.12.22.21267952
https://doi.org/10.1101/2021.12.22.21267952
Autor:
Katia de Paiva Lopes, Gijsje J. L. Snijders, Jack Humphrey, Amanda Allan, Marjolein A. M. Sneeboer, Elisa Navarro, Brian M. Schilder, Ricardo A. Vialle, Madison Parks, Roy Missall, Welmoed van Zuiden, Frederieke A. J. Gigase, Raphael Kübler, Amber Berdenis van Berlekom, Emily M. Hicks, Chotima Bӧttcher, Josef Priller, René S. Kahn, Lot D. de Witte, Towfique Raj
Publikováno v:
Nature genetics. 54(1)
Microglia have emerged as important players in brain aging and pathology. To understand how genetic risk for neurological and psychiatric disorders is related to microglial function, large transcriptome studies are essential. Here we describe the tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37c4d9f4958280d38da5343e6c7b492
https://pubmed.ncbi.nlm.nih.gov/35228701
https://pubmed.ncbi.nlm.nih.gov/35228701
Autor:
Snijders Gjl, Marjolein A. M. Sneeboer, Chotima Böttcher, Josef Priller, Ricardo Assunção Vialle, de Witte Ld, Kübler R, Gigase F, Roy Missall, de Paiva Lopes K, Elisa Navarro, van Berlekom Ab, van Zuiden W, Madison Parks, Towfique Raj, René S. Kahn, Amanda Allan, Jack Humphrey, Brian M. Schilder
Microglial cells have emerged as potential key players in brain aging and pathology. To capture the heterogeneity of microglia across ages and regions, and to understand how genetic risk for neurological and psychiatric brain disorders is related to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47775d98fa39f8bab02757abe2474efd
https://doi.org/10.1101/2020.10.27.356113
https://doi.org/10.1101/2020.10.27.356113
Autor:
Charalambos Argyrou, Rachel Saunders-Pullman, Steven J. Frucht, Lotje de Witte, Towfique Raj, Ricardo Assunção Vialle, Ana C. Pereira, John F. Crary, Katia de Paiva Lopes, Ritesh A. Ramdhani, Evan Udine, Sarah Simon, Winona Tse, Brooklyn Henderson, Brian M. Schilder, Gijsje J. L. J. Snijders, Carolyn W. Zhu, Jack Humphrey, Susan Bressman, Kurt Farrell, Matthew Swan, Elisa Navarro, Ruth H. Walker, Deborah Raymond, Giulietta Riboldi, Vicki Shanker, Madison Parks, Tim Ahfeldt, Roberto A. Ortega, Alison Goate, Michael Chao, Maojuan Zhuang, Mary Sano, Amanda Allan, Sonya Elango, Tamjeed Sikder
An increasing number of identified Parkinson’s disease (PD) risk loci contain genes highly expressed in innate immune cells, yet their potential role in pathological mechanisms is not obvious. We have generated transcriptomic profiles of CD14+monoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b39620c005a7f4c54b389c1e2852834a
https://doi.org/10.1101/2020.07.20.212407
https://doi.org/10.1101/2020.07.20.212407
Autor:
Towfique Raj, Brian M. Schilder, Jack Humphrey, Katia de Paiva Lopes, Josef Priller, Roy Missall, Lot de Witte, Madison Parks, Chotima Böttcher, Marjolein A. M. Sneeboer, Raphael Kubler, Ricardo Assunção Vialle, G. Snijders, Amber Berdenis van Berlekom, René S. Kahn, Amanda Allan, Elisa Navarro, Welmoed van Zuiden, Frederieke Gigase
Publikováno v:
Biological Psychiatry. 89:S84-S85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf80ef6ad167848fc2f3059b28481f76
https://doi.org/10.1016/j.biopsych.2021.02.225
https://doi.org/10.1016/j.biopsych.2021.02.225
Autor:
Matthew D. Lloyd, Andrew S. Thompson, Thomas J. Hutchings, Michael D. Threadgill, Xiao Qu, Grace Chui, Wai Y. Leung, Amanda Allan, Lawrence Johnson, Ping Jiao, Georgina R. Steel, Timothy J. Woodman, Portia K. Li
Publikováno v:
Qu, X, Allan, A, Chui, G, Hutchings, T J, Jiao, P, Johnson, L, Leung, W Y, Li, P K, Steel, G R, Thompson, A S, Threadgill, M D, Woodman, T J & Lloyd, M D 2013, ' Hydrolysis of ibuprofenoyl-CoA and other 2-APA-CoA esters by human acyl-CoA thioesterases-1 and-2 and their possible role in the chiral inversion of profens ', Biochemical Pharmacology, vol. 86, no. 11, pp. 1621-1625 . https://doi.org/10.1016/j.bcp.2013.08.067
Ibuprofen and related 2-arylpropanoic acid (2-APA) drugs are often given as a racemic mixture and the R-enantiomers undergo activation in vivo by metabolic chiral inversion. The chiral inversion pathway consists of conversion of the drug to the coenz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f91323a93f0487c62ca5705993bbe55
https://doi.org/10.1016/j.bcp.2013.08.067
https://doi.org/10.1016/j.bcp.2013.08.067
Autor:
Amanda Allan, Allan Hewitt
Publikováno v:
International Journal of Music Education. 31:257-275
The experiences of 72 adolescent musicians who had been members of an advanced youth symphony orchestra or concert band were investigated. An online survey explored previous participation and the importance of past experiences when making future deci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db805c54856cbca0a34c113f2a6f5643
https://doi.org/10.1177/0255761411434494
https://doi.org/10.1177/0255761411434494
Autor:
Nick Haslam, Amanda Allan
Publikováno v:
The Encyclopedia of Peace Psychology
Humanitarian workers are people who work in theaters of humanitarian crisis that may have been instigated by natural environmental disasters, famine, conflict, or epidemics. These events invariably threaten the homes, livelihoods, safety, security, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c52dd8bca5f55c7f5fbaa906b121e347
https://doi.org/10.1002/9780470672532.wbepp130
https://doi.org/10.1002/9780470672532.wbepp130