Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Amanda Acosta-Ruiz"'
Autor:
Guoqing, Xiang, Amanda, Acosta-Ruiz, Arthur, Radoux-Mergault, Melanie, Kristt, Jihye, Kim, Jared D, Moon, Johannes, Broichhagen, Asuka, Inoue, Francis S, Lee, Miriam, Stoeber, Jeremy S, Dittman, Joshua, Levitz
Publikováno v:
Science advances. 8(47)
Numerous processes contribute to the regulation of G protein-coupled receptors (GPCRs), but relatively little is known about rapid mechanisms that control signaling on the seconds time scale or regulate cross-talk between receptors. Here, we reveal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2523583945a57b8ee79f3e92cc09f573
https://pubmed.ncbi.nlm.nih.gov/36427324
https://pubmed.ncbi.nlm.nih.gov/36427324
Autor:
Guoqing Xiang, Amanda Acosta-Ruiz, Arthur Radoux-Mergault, Melanie Kristt, Jihye Kim, Jared D. Moon, Johannes Broichhagen, Asuka Inoue, Francis S. Lee, Miriam Stoeber, Jeremy S. Dittman, Joshua Levitz
Publikováno v:
Science Advances. 8
Numerous processes contribute to the regulation of G protein–coupled receptors (GPCRs), but relatively little is known about rapid mechanisms that control signaling on the seconds time scale or regulate cross-talk between receptors. Here, we reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f480549ce02e677c19e8c3c5498883c
https://doi.org/10.1126/sciadv.abq3363
https://doi.org/10.1126/sciadv.abq3363
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92f48d33915c7a3a2ac30402dfa595a9
https://doi.org/10.1096/fasebj.2022.36.s1.r5050
https://doi.org/10.1096/fasebj.2022.36.s1.r5050
Autor:
Stephanie Häfner, Joshua Levitz, Jürgen Mony, Bettina Mathes, Karl Börjesson, Dzianis Yarotski, Vanessa A. Gutzeit, Johannes Broichhagen, Arnaud Landra-Willm, Amanda Acosta-Ruiz, Conor Liston, Hermany Munguba, Guillaume Sandoz
Publikováno v:
Cell Chem Biol
Cell Chemical Biology
Cell Chemical Biology
Summary Despite the power of photopharmacology for interrogating signaling proteins, many photopharmacological systems are limited by their efficiency, speed, or spectral properties. Here, we screen a library of azobenzene photoswitches and identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0319fd005c9c7e3b658395a9d6cfc880
https://europepmc.org/articles/PMC8435545/
https://europepmc.org/articles/PMC8435545/
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a1c519e5d963e936cd85096d1d8c827
https://doi.org/10.1096/fasebj.2019.33.1_supplement.503.20
https://doi.org/10.1096/fasebj.2019.33.1_supplement.503.20
Autor:
Joon Lee, Vanessa A. Gutzeit, Joshua Levitz, Puja K. Parekh, Anna G. Orr, Amanda Acosta-Ruiz, Johannes Broichhagen, Conor Liston, Kristen E. Pleil, Samantha Meadows, Mary Jane Skelly
Publikováno v:
Neuron
Summary The limitations of classical drugs have spurred the development of covalently tethered photoswitchable ligands to control neuromodulatory receptors. However, a major shortcoming of tethered photopharmacology is the inability to obtain optical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfb634564363fba787ab21d204bac0c
https://pubmed.ncbi.nlm.nih.gov/32027826
https://pubmed.ncbi.nlm.nih.gov/32027826
Autor:
Vanessa A. Gutzeit, Anna G. Orr, Joshua Levitz, Mary Jane Skelly, Kristen E. Pleil, Amanda Acosta-Ruiz, Joon Lee, Johannes Broichhagen, Samantha Meadows
The limitations of classical, soluble drugs in terms of subtype-specificity, spatiotemporal precision, and genetic targeting have spurred the development of advanced pharmacological techniques, including the use of covalently-tethered photoswitchable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c1a2e1afee1cbfde433f8ae53aa81a
Publikováno v:
Cell Reports. 35:109050
G protein-coupled receptors (GPCRs) interact with intracellular transducers to control both signal initiation and desensitization, but the distinct mechanisms that control the regulation of different GPCR subtypes are unclear. Here we use fluorescenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc60ee7e5399464cca041c75d964af9
https://doi.org/10.1016/j.celrep.2021.109050
https://doi.org/10.1016/j.celrep.2021.109050
Autor:
Geoffrey G. Hesketh, David J. Owen, Dorothy C. Bennett, J. Paul Luzio, Michael S. Marks, Graça Raposo, Elena V. Sviderskaya, Cédric Delevoye, Megan K. Dennis, Amanda Acosta-Ruiz, Philip S. Goff, Ilse Hurbain, Thierry Galli, Maryse Romao
Publikováno v:
The Journal of Cell Biology
Dennis et al. analyze cycling of the v-SNARE VAMP7 during melanosome biogenesis in melanocytes. VAMP7 is targeted to and retrieved from maturing melanosomes in separate tubular carriers whose formation requires distinct BLOCs, each defective in varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb08332738c45352df80194d98b5d17
https://doi.org/10.1083/jcb.201605090
https://doi.org/10.1083/jcb.201605090
Autor:
Joshua Levitz, Vanessa A. Gutzeit, Johannes Broichhagen, Amanda Acosta Ruiz, Conor Liston, Melanie Kristt
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a6af48448dc0fd791e3fae668f95846
https://doi.org/10.1096/fasebj.2020.34.s1.05430
https://doi.org/10.1096/fasebj.2020.34.s1.05430