Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amanda Ackley"'
Autor:
Surya Shrivastava, Paige Charlins, Amanda Ackley, Heather Embree, Boro Dropulic, Ramesh Akkina, Marc S. Weinberg, Kevin V. Morris
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 12-18 (2018)
Gene-based therapies represent a promising treatment for HIV-1 infection, as they offer the potential for sustained viral inhibition and reduced treatment interventions. One approach developed here involves using conditionally replicating vectors (CR
Externí odkaz:
https://doaj.org/article/e74d2a043e264b8aad17ef2026f78ab7
Autor:
Amanda Ackley, Alexandra Lenox, Kenneth Stapleton, Stuart Knowling, Tim Lu, Kenny S Sabir, Peter K Vogt, Kevin V Morris
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Small noncoding antisense RNAs (sasRNAs) guide epigenetic silencing complexes to target loci in human cells and modulate gene transcription. When these targeted loci are situated within a promoter, long-term, stable epigenetic silencing of transcript
Externí odkaz:
https://doaj.org/article/20c51ae8a73c411c98bf011a2eeb55d1
Autor:
Heather Embree, Marc S. Weinberg, Surya Shrivastava, Amanda Ackley, Kevin V. Morris, Ramesh Akkina, Boro Dropulic, Paige Charlins
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 12-18 (2018)
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 12-18 (2018)
Gene-based therapies represent a promising treatment for HIV-1 infection, as they offer the potential for sustained viral inhibition and reduced treatment interventions. One approach developed here involves using conditionally replicating vectors (CR
Autor:
Kevin V. Morris, Sheena Saayman, Pad Chivukula, Amanda Ackley, Jon Burdach, Kiyoshi Tachikawa, Dieter C. Gruenert, Matthew Clemson, Marc S. Weinberg
Publikováno v:
Molecular Therapy
Cystic fibrosis (CF) is a life-shortening genetic disease. The root cause of CF is heritable recessive mutations that affect the cystic fibrosis transmembrance conductance regulator (CFTR) gene and the subsequent expression and activity of encoded io
Publikováno v:
Human Gene Therapy. 23:473-483
Small antisense RNAs targeted to the HIV-1 promoter have been shown to remodel the surrounding chromatin to a state unfavorable for transcriptional activation, yet transcriptional gene silencing (TGS) of HIV-1 has, to date, not been shown in primary
Autor:
Paige Charlins, Uriel A López-Lemus, Marc S. Weinberg, Amanda Ackley, Heather Embree, Kevin V. Morris, Sheena Saayman, Boro Dropulic, Ramesh Akkina
Publikováno v:
Molecular Therapy. 24:S213
Gene-based therapies represent a promising therapeutic paradigm for the treatment of HIV, as they have the potential for sustained viral inhibition via reduced treatment interventions. One innovative approach developed here involves using conditional
Autor:
Martin Corcoran, Amanda Ackley, Per Johnsson, Linda Vidarsdottir, Kevin V. Morris, Dan Grandér, Weng-Onn Lui
Publikováno v:
Nature structural & molecular biology
PTEN is a tumor-suppressor gene that has been shown to be under the regulatory control of a PTEN pseudogene expressed noncoding RNA, PTENpg1. Here, we characterize a previously unidentified PTENpg1-encoded antisense RNA (asRNA), which regulates PTEN
Autor:
Peter K. Vogt, Amanda Ackley, Stuart Knowling, Alexandra Lenox, Tim Lu, Kenny S Sabir, Kevin V. Morris, Kenneth Stapleton
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Small noncoding antisense RNAs (sasRNAs) guide epigenetic silencing complexes to target loci in human cells and modulate gene transcription. When these targeted loci are situated within a promoter, long-term, stable epigenetic silencing of transcript