Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Amanda, de Fraga Dias"'
Autor:
Vitória Brum da Silva Nunes, Camila Kehl Dias, Juliete Nathali Scholl, Alexia Nedel Sant’Ana, Amanda de Fraga Dias, Mariela Granero Farias, Ana Paula Alegretti, Monalisa Sosnoski, Liane Esteves Daudt, Mariana Bohns Michalowski, Ana Maria Oliveira Battastini, Alessandra Aparecida Paz, Fabrício Figueiró
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Purpose Although risk-stratified chemotherapy regimens improve B-cell acute lymphoblastic leukemia (B-ALL) clinical outcome, relapse occurs in a significant number of cases. The identification of new therapeutic targets as well as prognostic
Externí odkaz:
https://doaj.org/article/3a581ca919d8488aa265a987c716ea9d
Autor:
Pedro Vargas, Thamiris Becker Scheffel, Fernando Mendonça Diz, Liliana Rockenbach, Nathália Grave, Angélica Regina Cappellari, Luiza Wilges Kist, Maurício Reis Bogo, Marcos Paulo Thomé, Gabriel Fernandes Leal, Amanda de Fraga Dias, Fabrício Figueiró, Eduardo Cremonese Filippi-Chiela, Guido Lenz, Fernanda Bueno Morrone
Publikováno v:
Purinergic Signalling. 18:481-494
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e71f3eca724babdcf65da474dd9ef185
https://doi.org/10.1007/s11302-022-09888-w
https://doi.org/10.1007/s11302-022-09888-w
Autor:
Aline de Cristo Soares Alves, Ana Maria Oliveira Battastini, Fabrício Figueiró, Silvia Stanisçuaski Guterres, Vladimir Lavayen, Fernanda Visioli, Amanda de Fraga Dias, Adriana Raffin Pohlmann, Franciele Aline Bruinsmann, Rodrigo Cé, Juliete Nathali Scholl
Publikováno v:
Nanomedicine. 16:1775-1790
Aim: To evaluate the antitumor efficacy of bevacizumab-functionalized nanocapsules in a rat glioblastoma model after the pretreatment with nanocapsules functionalized with a peptide-specific to the epidermal growth factor receptor variant III. Materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e596e6c809d2c4f6a8cafdb4405f2dd
https://doi.org/10.2217/nnm-2021-0169
https://doi.org/10.2217/nnm-2021-0169
Autor:
Leonardo B Federico, Amanda de Fraga Dias, Ana Maria Oliveira Battastini, Guilherme Martins Silva, Fabrício Figueiró, Luciano T. Costa, Joaquín Maria Carmpos Rosa, Cleydson B. R. Santos, Carlos Henrique Tomich de Paula da Silva
Publikováno v:
International Journal of Biological Macromolecules. 165:3040-3050
Among several strategies related to cancer therapy targeting the modulation of αβ-tubulin has shown encouraging findings, more specifically when this is achieved by inhibitors located at the colchicine binding site. In this work, we aim to fish new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b1b113da2c8d53a82106fcd44b069f
https://doi.org/10.1016/j.ijbiomac.2020.10.136
https://doi.org/10.1016/j.ijbiomac.2020.10.136
Autor:
Pedro, Vargas, Thamiris Becker, Scheffel, Fernando Mendonça, Diz, Liliana, Rockenbach, Nathália, Grave, Angélica Regina, Cappellari, Luiza Wilges, Kist, Maurício Reis, Bogo, Marcos Paulo, Thomé, Gabriel Fernandes, Leal, Amanda, de Fraga Dias, Fabrício, Figueiró, Eduardo Cremonese, Filippi-Chiela, Guido, Lenz, Fernanda Bueno, Morrone
Publikováno v:
Purinergic Signal
Glioblastoma (GBM) is the most aggressive and lethal among the primary brain tumors, with a low survival rate and resistance to radio and chemotherapy. The P2Y(12) is an adenosine diphosphate (ADP) purinergic chemoreceptor, found mainly in platelets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9a79b8d08d0f9c9522c5f5050a0d2af
https://pubmed.ncbi.nlm.nih.gov/35939198
https://pubmed.ncbi.nlm.nih.gov/35939198
Autor:
Fabrício Figueiró, Ivone Carvalho, Carlos Henrique Tomich de Paula da Silva, Fernando Cidade Torres, Peterson de Andrade, Daniel Fábio Kawano, Joaquín M. Campos, Amanda de Fraga Dias, Ana Maria Oliveira Battastini
Publikováno v:
Future Medicinal Chemistry. 12:689-708
Aim: Glioblastoma multiforme (GBM) is an aggressive cancer with very limited clinical therapies. Herein, we have designed novel mercaptobenzimidazole derivatives (1–7) as multitarget antineoplastic drugs and assessed their antiproliferative profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aef889edf06aeff519d8f55973e568a
https://doi.org/10.4155/fmc-2019-0227
https://doi.org/10.4155/fmc-2019-0227
Autor:
Franciele Aline Bruinsmann, Aline de Cristo Soares Alves, Amanda de Fraga Dias, Luiz Fernando Lopes Silva, Fernanda Visioli, Adriana Raffin Pohlmann, Fabrício Figueiró, Fabio Sonvico, Silvia Stanisçuaski Guterres
Publikováno v:
International journal of pharmaceutics. 616
Glioblastoma is the most common and lethal malignant brain tumor. Despite simvastatin (SVT) showing potential anticancer properties, its antitumoral effect against glioblastoma appears limited when the conventional oral administration route is select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af5b797bee705a35842f38f56bdae1b
https://pubmed.ncbi.nlm.nih.gov/35151819
https://pubmed.ncbi.nlm.nih.gov/35151819
Autor:
Ana Maria Oliveira Battastini, Franciele Aline Bruinsmann, Ana Conejo-García, Luiz Fernando Lopes Silva, Danieli Rosane Dallemole, Joaquín M. Campos, Amanda de Fraga Dias, Silvia Stanisçuaski Guterres, Adriana Raffin Pohlmann, Olga Cruz-Lopez, Fabrício Figueiró
Publikováno v:
Nanomedicine (London, England). 16(23)
Aim: To develop and characterize bozepinib-loaded lipid-core nanocapsules (BZP-LNC+) as a potential treatment for glioblastoma (GBM). Methods: Characterization of nanocapsules was performed by diameter, polydispersity index, Zeta potential, pH and en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1d7279fe513c975067caea2ace5ff7
https://pubmed.ncbi.nlm.nih.gov/34523353
https://pubmed.ncbi.nlm.nih.gov/34523353
Autor:
Cesar Eduardo Jacintho Moritz, Ana Maria Oliveira Battastini, Alvaro Reischak-Oliveira, Amanda de Fraga Dias, Franccesco Pinto Boeno, Samuel Vargas Munhoz, Juliete Nathali Scholl, Alexandra Ferreira Vieira, Pauline Rafaela Pizzato, Fabrício Figueiró
Publikováno v:
Experimental physiologyREFERENCES. 106(4)
New finding What is the central question of this study? How does moderate-intensity aerobic exercise affect the behaviour of purinergic enzymes in sedentary, overweight and physically active subjects? What is the relationship between purinergic and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7c6d27fa896582804296385752aa49
https://pubmed.ncbi.nlm.nih.gov/33624912
https://pubmed.ncbi.nlm.nih.gov/33624912
Autor:
Daniela Vasconcelos Lopes, Luiz Fernando Lopes Silva, Jean Sévigny, Fabrício Figueiró, Ana Maria Oliveira Battastini, Amanda de Fraga Dias, Juliete Nathali Scholl
Publikováno v:
Purinergic Signal
Glioblastoma (GBM) is the most malignant and deadly brain tumor. GBM cells overexpress the CD73 enzyme, which controls the level of extracellular adenosine, an immunosuppressive molecule. Studies have shown that some nonsteroidal anti-inflammatory dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3068bc11041ed1fc51f77df0a2fad21
https://pubmed.ncbi.nlm.nih.gov/33745072
https://pubmed.ncbi.nlm.nih.gov/33745072