Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Amanda, Zucker"'
Autor:
Haochen Zhang, Elias-Ramzey Karnoub, Shigeaki Umeda, Ronan Chaligné, Ignas Masilionis, Caitlin A. McIntyre, Palash Sashittal, Akimasa Hayashi, Amanda Zucker, Katelyn Mullen, Jungeui Hong, Alvin Makohon-Moore, Christine A. Iacobuzio-Donahue
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Implementing high-throughput single-cell DNA sequencing for the study of solid tumours has been challenging. Here, the authors present an optimised approach for snap-frozen tissue single nuclei extraction and DNA sequencing, which can be applied to s
Externí odkaz:
https://doaj.org/article/f547a2f202d1496d9bde6d8b1e24f513
Autor:
Johnny Kao, Mark K. Farrugia, Samantha Frontario, Amanda Zucker, Emily Copel, John Loscalzo, Ashish Sangal, Boramir Darakchiev, Anurag Singh, Symeon Missios
Publikováno v:
Cancer Medicine, Vol 10, Iss 22, Pp 7934-7942 (2021)
Abstract Background Patients with metastatic cancer referred to radiation oncology have diverse prognoses and there is significant interest in personalizing treatment. We hypothesized that patients selected for higher biologically equivalent doses ha
Externí odkaz:
https://doaj.org/article/b60aae74b41344d391e385811cd109f8
Autor:
Johnny, Kao, Amanda, Zucker, Michelle, Urso, Pawel, Karwowski, Neha, Jain, Shourya, Jain, Giovanna, Bustamante, Deborah, Lugo, Luann, Rowland
Publikováno v:
Anticancer Research. 42:1397-1401
NEAT is a validated prognostic model that calculates survival estimates based on the number of active tumors, ECOG performance status, albumin, and primary tumor site. Since models are imperfect, we hypothesized that experienced clinicians could pred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f227a780ba202446957c8fd9276ee6fc
https://doi.org/10.21873/anticanres.15609
https://doi.org/10.21873/anticanres.15609
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Figure S5 shows the Jaccard similarity coefficients across the seven melanoma cases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db7d12acbce5e61cdbd8d5ee4d5c9f6
https://doi.org/10.1158/1078-0432.22479740
https://doi.org/10.1158/1078-0432.22479740
Tables S1-S8 from The Genetic Evolution of Treatment-Resistant Cutaneous, Acral, and Uveal Melanomas
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Supplementary Tables S1-S8 show the samples used for study (Table S1), the somatic single nucleotide variants, small insertions and small deletions (Table S2), the somatic copy number alterations anallyzed (Table S3), the gene list used to analyze so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152b4139b47cb30c51b6cd5befd1a5b0
https://doi.org/10.1158/1078-0432.22479734.v1
https://doi.org/10.1158/1078-0432.22479734.v1
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Purpose:Melanoma is a biologically heterogeneous disease composed of distinct clinicopathologic subtypes that frequently resist treatment. To explore the evolution of treatment resistance and metastasis, we used a combination of temporal and multiles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6224543d5704e454172689636f33e8cd
https://doi.org/10.1158/1078-0432.c.6530294
https://doi.org/10.1158/1078-0432.c.6530294
Autor:
Anurag K. Singh, Emily Copel, Amanda Zucker, Boramir Darakchiev, Mark K. Farrugia, Symeon Missios, John Loscalzo, Ashish Sangal, Samantha Frontario, Johnny Kao
Publikováno v:
Cancer Medicine, Vol 10, Iss 22, Pp 7934-7942 (2021)
Cancer Medicine
Cancer Medicine
Background Patients with metastatic cancer referred to radiation oncology have diverse prognoses and there is significant interest in personalizing treatment. We hypothesized that patients selected for higher biologically equivalent doses have improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6827501058488bccf4dad9163cf09a
https://doi.org/10.1002/cam4.4304
https://doi.org/10.1002/cam4.4304
Autor:
Haochen Zhang, Elias-Ramzey Karnoub, Shigeaki Umeda, Ronan Chaligné, Ignas Masilionis, Caitlin McIntyre, Akimasa Hayashi, Palash Sashittal, Amanda Zucker, Katelyn Mullen, Alvin Makohon-Moore, Christine Iacobuzio-Donahue
Despite insights gained by bulk DNA sequencing of cancer it remains challenging to resolve the admixture of normal and tumor cells, and/or of distinct tumor subclones; high throughput single-cell DNA sequencing circumvents these and brings cancer gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edda59311b5dfc2bac8c110ef930713d
https://doi.org/10.1101/2022.03.06.483206
https://doi.org/10.1101/2022.03.06.483206
Autor:
Jinlong Huang, Shinya Oki, Akimasa Hayashi, Johannes G. Reiter, Jerry P. Melchor, Yu-Jui Ho, Lance Zhang, Priscilla Baez, Marc A. Attiyeh, Amanda Zucker, Alvin Makohon-Moore, Rajya Kappagantula, Eileen M. O'Reilly, Scott W. Lowe, Jungeui Hong, Christine A. Iacobuzio-Donahue, Nicholas D. Socci
While the non-coding genome appears to play a role, the dynamic nature of noncoding alterations with respect to clonal progression of solid tumors remains unexplored. To address this gap in knowledge we performed multiregional whole genome sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e22e36ebb43c6eb2219e7515503895d2
https://doi.org/10.1101/2020.09.11.294389
https://doi.org/10.1101/2020.09.11.294389
Autor:
Amanda Zucker, Christine A. Iacobuzio-Donahue, Rachel Karchin, Jody E. Hooper, Vladimir Makarov, Nicholas D. Socci, Timothy A. Chan, Paul B. Chapman, Barry S. Taylor, Jungeui Hong, Suzanne L. Topalian, Michael A. Postow, Priscilla Baez, Rajya Kappagantula, David B. Solit, Akimasa Hayashi, Zachary Kohutek, Nadeem Riaz, Collin Tokheim, Alvin Makohon-Moore, Craig M. Bielski, Evan J. Lipson
Publikováno v:
Clin Cancer Res
Purpose: Melanoma is a biologically heterogeneous disease composed of distinct clinicopathologic subtypes that frequently resist treatment. To explore the evolution of treatment resistance and metastasis, we used a combination of temporal and multile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5755ec159b365ac6169f357679e443ac
https://pubmed.ncbi.nlm.nih.gov/33323400
https://pubmed.ncbi.nlm.nih.gov/33323400