Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Amanda, Mabhula"'
Autor:
Laura Noël-Romas, Michelle Perner, Refilwe Molatlhegi, Christina Farr Zuend, Amanda Mabhula, Sarah Hoger, Alana Lamont, Kenzie Birse, Alicia Berard, Stuart McCorrister, Garett Westmacott, Al Leslie, Vanessa Poliquin, Renee Heffron, Lyle R McKinnon, Adam D Burgener
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009097 (2020)
Alterations to the mucosal environment of the female genital tract, such as genital inflammation, have been associated with increased HIV acquisition in women. As the microbiome and hormonal contraceptives can affect vaginal mucosal immunity, we hypo
Externí odkaz:
https://doaj.org/article/4aa8c2a61e09450bbe96238e45e65caa
Autor:
Dickson Mambwe, Constance M. Korkor, Amanda Mabhula, Zama Ngqumba, Cleavon Cloete, Malkeet Kumar, Paula Ladeia Barros, Meta Leshabane, Dina Coertzen, Dale Taylor, Liezl Gibhard, Mathew Njoroge, Nina Lawrence, Janette Reader, Diogo Rodrigo Moreira, Lyn-Marie Birkholtz, Sergio Wittlin, Timothy J. Egan, Kelly Chibale
Publikováno v:
Journal of Medicinal Chemistry. 65:16695-16715
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be13f3671115eb74fe7def09b01a1d32
https://doi.org/10.1021/acs.jmedchem.2c01516
https://doi.org/10.1021/acs.jmedchem.2c01516
Publikováno v:
ACS Infectious Diseases. 7:2437-2444
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a major global health concern given the increase in multiple forms of drug-resistant TB. This underscores the importance of a continuous pipeline of new anti-TB agents. Drug repurposing has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e97a4cd4b22b74e310632c4a4d2f5ef5
https://doi.org/10.1021/acsinfecdis.1c00195
https://doi.org/10.1021/acsinfecdis.1c00195
Autor:
Ujjini H. Manjunatha, Christel Brunschwig, Mathew Njoroge, Srinivasa P. S. Rao, Nina Lawrence, Dale Taylor, Rudolf Müller, Kelly Chibale, Paul M. Njaria, Renier van der Westhuyzen, Vinayak Singh, Leslie J. Street, Amanda Mabhula, Atica Moosa, Digby F. Warner, Denis Ngumbu Muhunga, Paul W. Smith
Publikováno v:
Journal of Medicinal Chemistry. 64:9444-9457
Screening of a library of small polar molecules against Mycobacterium tuberculosis (Mtb) led to the identification of a potent benzoheterocyclic oxime carbamate hit series. This series was subjected to medicinal chemistry progression underpinned by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f22b2b0b4cd9366307e089958a09622f
https://doi.org/10.1021/acs.jmedchem.1c00707
https://doi.org/10.1021/acs.jmedchem.1c00707
Publikováno v:
ACS infectious diseases. 7(8)
Tuberculosis (TB), caused by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::665c3d08185beb6cc39e6213415b452d
https://pubmed.ncbi.nlm.nih.gov/34196521
https://pubmed.ncbi.nlm.nih.gov/34196521
Autor:
Vinayak Singh, Amanda Mabhula
Publikováno v:
MedChemComm. 10:1342-1360
Tuberculosis (TB), an infectious disease caused by the bacterium Mycobacterium tuberculosis (Mtb), has burdened vulnerable populations in modern day societies for decades. Recently, this global health threat has been heightened by the emergence and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d1eba152c857163fcb58d1ef52d5835
https://doi.org/10.1039/c9md00057g
https://doi.org/10.1039/c9md00057g
Autor:
Renier, van der Westhuyzen, Amanda, Mabhula, Paul M, Njaria, Rudolf, Müller, Denis, Ngumbu Muhunga, Dale, Taylor, Nina, Lawrence, Mathew, Njoroge, Christel, Brunschwig, Atica, Moosa, Vinayak, Singh, Srinivasa P S, Rao, Ujjini H, Manjunatha, Paul W, Smith, Digby F, Warner, Leslie J, Street, Kelly, Chibale
Publikováno v:
Journal of medicinal chemistry. 64(13)
Screening of a library of small polar molecules against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03d111d78c2e649bf21f94024eb5cf31
https://pubmed.ncbi.nlm.nih.gov/34138573
https://pubmed.ncbi.nlm.nih.gov/34138573
Autor:
Samkelisiwe Ngcobo, Sinaye Ngcapu, Natasha Samsunder, Jo-Ann S. Passmore, John H. Adamson, Lyle R. McKinnon, Mthobisi M Zondi, Lenine J. P. Liebenberg, Alasdair Leslie, Amanda Mabhula, Salim S. Abdool Karim, Quarraisha Abdool Karim, Nobuhle Nokubonga Mchunu, Katya Govender, Aida Sivro, Refilwe P Molatlhegi
Publikováno v:
American Journal of Reproductive Immunology.
PROBLEM Injectable hormonal contraceptives (IHC) have been associated with altered mucosal and systemic milieu which might increase HIV risk, but most studies have focused on DMPA and not NET-EN, despite the growing popularity and lower HIV risk asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d7c56648394aea12e4486857ba7a48
https://doi.org/10.1111/aji.13411
https://doi.org/10.1111/aji.13411
Autor:
Nobuhle Mchunu, Amanda Mabhula, Adam Burgener, Refilwe P Molatlhegi, Jo-Ann S. Passmore, Michelle Perner, Salim S. Abdool Karim, Sinaye Ngcapu, Alasdair Leslie, Lenine J. P. Liebenberg, Laura Noël-Romas, Natasha Samsunder, Kenzie Birse, Lyle R. McKinnon, Katya Govender, Nigel Garrett, John H. Adamson, Quarraisha Abdool Karim
Publikováno v:
Mucosal immunology. 13(3)
Long-acting injectable contraceptives have been associated with mucosal immune changes and increased HIV acquisition, but studies have often been hampered by the inaccuracy of self-reported data, unknown timing of injection, and interactions with muc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a8e7092b2d3d5374d071cbcd0e70b6
https://pubmed.ncbi.nlm.nih.gov/31896762
https://pubmed.ncbi.nlm.nih.gov/31896762
Autor:
Amanda, Mabhula, Vinayak, Singh
Publikováno v:
Medchemcomm
Tuberculosis (TB), an infectious disease caused by the bacterium Mycobacterium tuberculosis (Mtb), has burdened vulnerable populations in modern day societies for decades. Recently, this global health threat has been heightened by the emergence and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::861b7499a7018cd6f45f4fe9b74e6f5d
https://pubmed.ncbi.nlm.nih.gov/31534654
https://pubmed.ncbi.nlm.nih.gov/31534654