Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Amanda, Hutchins"'
Autor:
Reuben J. Shaw, Rebecca Berdeaux, Robert A. Screaton, Maxim N. Shokhirev, April E. Williams, Hector M. Galvez, Amanda Hutchins, T.J. Rymoff, Debbie S. Ross, Liliana I. Vera, Robert U. Svensson, Anwesh Kamireddy, Sonja N. Brun, Lillian J. Eichner, Pablo E. Hollstein
Supplemental Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004e8302e03d44f61ec3ba546c257239
https://doi.org/10.1158/2159-8290.22532756
https://doi.org/10.1158/2159-8290.22532756
Autor:
Reuben J. Shaw, Rebecca Berdeaux, Robert A. Screaton, Maxim N. Shokhirev, April E. Williams, Hector M. Galvez, Amanda Hutchins, T.J. Rymoff, Debbie S. Ross, Liliana I. Vera, Robert U. Svensson, Anwesh Kamireddy, Sonja N. Brun, Lillian J. Eichner, Pablo E. Hollstein
Mutations in the LKB1 (also known as STK11) tumor suppressor are the third most frequent genetic alteration in non–small cell lung cancer (NSCLC). LKB1 encodes a serine/threonine kinase that directly phosphorylates and activates 14 AMPK family kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88f344e09faf5fe67fa60dbf2d0358c
https://doi.org/10.1158/2159-8290.c.6546818
https://doi.org/10.1158/2159-8290.c.6546818
Autor:
Jiawei Wang, Mursal Nader, Can Cui, Martina Damo, Achia Khatun, Ivana William, Julie F. Cheung, Nikhil S. Joshi, Eric Fagerberg, Smita Krishnaswamy, Amanda Hutchins, Gena G. Foster, Weiguo Cui, Isabel Monroy, Moujtaba Y. Kasmani, Aarthi Venkat, Brittany Fitzgerald, Hongyu Zhao, Manik Kuchroo, Kelli A. Connolly, Noah I. Hornick, Dylan L. Mariuzza
Publikováno v:
Science Immunology. 6
Tumor-specific CD8 + T cells in stable tumor-draining lymph node reservoir are clonally and developmentally related to those in tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41f715a2520f1cb44ad2833c27cb0906
https://doi.org/10.1126/sciimmunol.abg7836
https://doi.org/10.1126/sciimmunol.abg7836
Autor:
Kelli A, Connolly, Manik, Kuchroo, Aarthi, Venkat, Achia, Khatun, Jiawei, Wang, Ivana, William, Noah I, Hornick, Brittany L, Fitzgerald, Martina, Damo, Moujtaba Y, Kasmani, Can, Cui, Eric, Fagerberg, Isabel, Monroy, Amanda, Hutchins, Julie F, Cheung, Gena G, Foster, Dylan L, Mariuzza, Mursal, Nader, Hongyu, Zhao, Weiguo, Cui, Smita, Krishnaswamy, Nikhil S, Joshi
Publikováno v:
Sci Immunol
“Stem-like” TCF1(+) CD8(+) T cells (T(SL)) are necessary for long-term maintenance of T cell responses and the efficacy of immunotherapy but, as tumors contain signals that should drive T-cell terminal-differentiation, how these cells are maintai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e6e92f53c1eaaa1f1c6306e7c6ecb7b
https://pubmed.ncbi.nlm.nih.gov/34597124
https://pubmed.ncbi.nlm.nih.gov/34597124
Autor:
Rebecca Berdeaux, Hector M. Galvez, Sonja N. Brun, T.J. Rymoff, Pablo E. Hollstein, Robert U. Svensson, Anwesh Kamireddy, Reuben J. Shaw, Robert A. Screaton, April Williams, Debbie S. Ross, Liliana I. Vera, Maxim N. Shokhirev, Amanda Hutchins, Lillian J. Eichner
Publikováno v:
Cancer Discov
Mutations in the LKB1 (also known as STK11) tumor suppressor are the third most frequent genetic alteration in non–small cell lung cancer (NSCLC). LKB1 encodes a serine/threonine kinase that directly phosphorylates and activates 14 AMPK family kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ee21e559bb0353fc4a7411b4d5c664
https://doi.org/10.1158/2159-8290.cd-18-1261
https://doi.org/10.1158/2159-8290.cd-18-1261
Autor:
Julie F. Cheung, Eric Fagerberg, Gena G. Foster, Noah I. Hornick, Dylan L. Mariuzza, Aarthi Venkat, Kelli A. Connolly, Ivana William, Amanda Hutchins, Weiguo Cui, Manik Kuchroo, Isabel Monroy, Jiawei Wang, Martina Damo, Achia Khatun, Moujtaba Y. Kasmani, Nikhil S. Joshi, Smita Krishnaswamy, Brittany Fitzgerald, Hongyu Zhao, Can Cui
“Stem-like” TCF1+CD8+T cells (TSL) are necessary for long-term maintenance of T cell responses and the efficacy of immunotherapy but, as tumors contain signals that should drive T-cell terminal-differentiation, how these cells are maintained in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a92da2441d764fae88781e256299859c
https://doi.org/10.1101/2021.01.27.428467
https://doi.org/10.1101/2021.01.27.428467
Autor:
Aarthi Venkat, Brittany Fitzgerald, Martina Damo, Achia Khatun, Nikhil S. Joshi, Isabel Monroy, Amanda Hutchins, Weiguo Cui, Kelli A. Connolly, Can Cui, Moujtaba Y. Kasmani, Manik Kuchroo, Smita Krishnaswamy
Publikováno v:
SSRN Electronic Journal.
Intratumoral stem-like CD8+ T cells (TSL) are necessary for immunotherapeutic efficacy. Yet, tumors are rich in signals driving terminal differentiation of TSL cells into exhausted T cells. Using the “KP-NINJA” lung tumor model, we determined tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3a77102b87a0e43abd2e43961006425
https://doi.org/10.2139/ssrn.3640763
https://doi.org/10.2139/ssrn.3640763
Autor:
Mathias Leblanc, Robert U. Svensson, Maxim N. Shokhirev, Lillian J. Eichner, David B. Shackelford, Amanda Hutchins, Sonja N. Brun, Sébastien Herzig, Debbie S. Ross, Reuben J. Shaw, Stephanie D. Curtis, Nathan P. Young, Liliana I. Vera
AMPK, a conserved sensor of low cellular energy. can either repress or promote tumor growth depending on the context. However, no studies have examined AMPK function in autochthonous genetic mouse models of epithelial cancer. Here, we examine the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb04a1f35ac51c8e3929bf096b49021
https://europepmc.org/articles/PMC6365213/
https://europepmc.org/articles/PMC6365213/
Autor:
Amanda Hutchins
From the development of the Blues, to the Civil Rights Movement, to the devastating effects of Hurricane Katrina, there have been a great number of changes, both good and bad, in Mississippi in the past century, and there are sure to be more to come.
Autor:
Reuben J. Shaw, Sathesh Bhat, Seth J. Parker, H. James Harwood, Jeremy R. Greenwood, Portia S. Lombardo, Sonja N. Brun, Robert U. Svensson, Matthew J. Kolar, Christian M. Metallo, William F. Westlin, Amanda Hutchins, Jeanine L. Van Nostrand, Martina Wallace, Rosana Kapeller, Lillian J. Eichner, Alan Saghatelian, Laurie Gerken, Lilliana Vera, Geraldine Harriman
Publikováno v:
Nature medicine, vol 22, iss 10
Continuous de novo fatty acid synthesis is a common feature of cancer that is required to meet the biosynthetic demands of a growing tumor. This process is controlled by the rate-limiting enzyme acetyl-CoA carboxylase (ACC), an attractive but traditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0d60dab900558853c35c1c76c67eb3
https://pubmed.ncbi.nlm.nih.gov/27807350
https://pubmed.ncbi.nlm.nih.gov/27807350