Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Aman Wang"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Amivantamab is the first dual-specificity antibody targeting EGFR and MET, which is approved for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with EGFR exon 20 insertion mutations. Cardiovascular toxicit
Externí odkaz:
https://doaj.org/article/c7162ac2772240ec8fb7c565b1663d60
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Glycan-based scaffolds are unique in their high specificity, versatility, low immunogenicity, and ability to mimic natural carbohydrates, making them attractive candidates for use in cancer treatment. These scaffolds are made up of glycans, which are
Externí odkaz:
https://doaj.org/article/75d83469e9ec42978cd8eca3148c0171
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundDiffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma and may occur with lymph node and/or extranodal involvement. However, DLBCL with intracardiac mass is exceedingly rare. In the reported literature, the
Externí odkaz:
https://doaj.org/article/412441e198b144969979a14bb7f38dc2
Autor:
Zhen Ning, Xin Guo, Xiaolong Liu, Chang Lu, Aman Wang, Xiaolin Wang, Wen Wang, Huan Chen, Wangshu Qin, Xinyu Liu, Lina Zhou, Chi Ma, Jian Du, Zhikun Lin, Haifeng Luo, Wuxiyar Otkur, Huan Qi, Di Chen, Tian Xia, Jiwei Liu, Guang Tan, Guowang Xu, Hai-long Piao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Different deubiquitinases are associated to cancer development. Here, the authors show that PPARgamma is stabilized by USP22-mediated deubiquitination leading to lipid accumulation and promoting hepatocellular carcinoma.
Externí odkaz:
https://doaj.org/article/7a0b38d3c50c4e26bad4fb004f16686a
Autor:
Chang Liu, Henan Qin, Huiying Liu, Tianfu Wei, Zeming Wu, Mengxue Shang, Haihua Liu, Aman Wang, Jiwei Liu, Dong Shang, Peiyuan Yin
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pancreatic cancer (PC) is burdened with a low 5-year survival rate and high mortality due to a severe lack of early diagnosis methods and slow progress in treatment options. To improve clinical diagnosis and enhance the treatment effects, we applied
Externí odkaz:
https://doaj.org/article/ebc043e307f4413c92ba58a4c8206858
Autor:
Lei Wang, Wuxiyar Otkur, Aman Wang, Wen Wang, Yitong Lyu, Lei Fang, Xiu Shan, Mingzhou Song, Yan Feng, Yi Zhao, Hai-Long Piao, Huan Qi, Ji-Wei Liu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Melanoma is the most aggressive type of skin cancer with a high incidence and low survival rate. More than half of melanomas present the activating BRAF mutations, along which V600E mutant represents 70%–90%. Vemurafenib (Vem) is an FDA-approved sm
Externí odkaz:
https://doaj.org/article/eeefd80a7dfe413293aaf6dcbcacfdb9
Publikováno v:
Heliyon, Vol 8, Iss 8, Pp e10116- (2022)
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive cancer, characterized by a high metastatic burden. RIO Kinase 3 (RIOK3) has been shown to promote invasion and metastasis of PDAC by cytoskeleton remodeling, but the exact mechanism i
Externí odkaz:
https://doaj.org/article/91026585587a4fc4b65119a8b699aedc
Autor:
Xin Guo, Aman Wang, Wen Wang, Ya Wang, Huan Chen, Xiaolong Liu, Tian Xia, Aijia Zhang, Di Chen, Huan Qi, Ting Ling, Hai‐long Piao, Hong‐jiang Wang
Publikováno v:
Molecular Oncology, Vol 15, Iss 2, Pp 642-656 (2021)
Dependence on glutamine and acceleration of fatty acid oxidation (FAO) are both metabolic characteristics of triple‐negative breast cancer (TNBC). With the rapid growth of tumors, accelerated glutamine catabolism depletes local glutamine, resulting
Externí odkaz:
https://doaj.org/article/0e8897cc31574eaeba947b65df6d933d
Autor:
Mohammed Safi, Mahmoud Al-Azab, Chenxing Jin, Dario Trapani, Salem Baldi, Salah Adlat, Aman Wang, Bashir Ahmad, Hamza Al-madani, Xiu Shan, Jiwei Liu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immune checkpoint inhibitors (ICIs) have revolutionized metastatic melanoma treatment, but our knowledge of ICI activity across age groups is insufficient. Patients in different age groups with advanced melanoma were selected based on the ICI approva
Externí odkaz:
https://doaj.org/article/e3bbedb1cd5b45c9be422cb26d540dfe
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Probiotic-based therapies have been shown to be beneficial for chemotherapy-induced mucositis. Previous research has demonstrated that a probiotic mixture (Bifidobacterium brevis, Lactobacillus acidophilus, Lactobacillus casei, and Streptococcus ther
Externí odkaz:
https://doaj.org/article/a9f9e598ac2a4979a128827853a4f935