Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Aman Seth"'
Autor:
Jennifer L. Kamens, Stephanie Nance, Cary Koss, Beisi Xu, Anitria Cotton, Jeannie W. Lam, Elizabeth A. R. Garfinkle, Pratima Nallagatla, Amelia M. R. Smith, Sharnise Mitchell, Jing Ma, Duane Currier, William C. Wright, Kanisha Kavdia, Vishwajeeth R. Pagala, Wonil Kim, LaShanale M. Wallace, Ji-Hoon Cho, Yiping Fan, Aman Seth, Nathaniel Twarog, John K. Choi, Esther A. Obeng, Mark E. Hatley, Monika L. Metzger, Hiroto Inaba, Sima Jeha, Jeffrey E. Rubnitz, Junmin Peng, Taosheng Chen, Anang A. Shelat, R. Kiplin Guy, Tanja A. Gruber
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
KMT2A rearranged infant acute lymphoblastic leukemia patients have a poor prognosis. Here, the authors use high throughput drug screening on primary infant specimens to identify a clinically active chemotherapy combination.
Externí odkaz:
https://doaj.org/article/2cd886b587c94bdaa2bd04fdff849913
Autor:
Jennifer L. Kamens, Stephanie Nance, Cary Koss, Beisi Xu, Anitria Cotton, Jeannie W. Lam, Elizabeth A. R. Garfinkle, Pratima Nallagatla, Amelia M. R. Smith, Sharnise Mitchell, Jing Ma, Duane Currier, William C. Wright, Kanisha Kavdia, Vishwajeeth R. Pagala, Wonil Kim, LaShanale M. Wallace, Ji-Hoon Cho, Yiping Fan, Aman Seth, Nathaniel Twarog, John K. Choi, Esther A. Obeng, Mark E. Hatley, Monika L. Metzger, Hiroto Inaba, Sima Jeha, Jeffrey E. Rubnitz, Junmin Peng, Taosheng Chen, Anang A. Shelat, R. Kiplin Guy, Tanja A. Gruber
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/9c447ea95d6141ec876fcaed7f440b4c
Autor:
Ilaria Iacobucci, Reiji Fukano, Jake D. Friske, Chunxu Qu, Laura J. Janke, Yaqi Zhao, Pradyuamna Baviskar, Emily A. Backhaus, Peter Chockley, Aman Seth, A. Douglas Laird, Anjali S. Advani, Charles G. Mullighan
Publikováno v:
Blood Advances. 6:3255-3259
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25f9614a0aee68c8c39546a9c752671
https://doi.org/10.1182/bloodadvances.2021004854
https://doi.org/10.1182/bloodadvances.2021004854
Autor:
Reiji Fukano, R. Coleman Lindsley, Elena Varotto, Burgess B. Freeman, Kirsten Dickerson, Harini Jogiraju, Debbie Payne-Turner, Anang A. Shelat, Laura J. Janke, Aman Seth, Chunxu Qu, Jiyang Yu, James A. Kennedy, Emily S. Hollis, Georgia E. Haggard, Sarah M. Morris, Yingzhe Wang, Benjamin L. Ebert, Charles G. Mullighan, Ilaria Iacobucci, Rena Zheng, Jake D. Friske, Xu Yang, Nina Ghosn, Adam S. Sperling
Publikováno v:
Blood. 137:1628-1640
Acute erythroid leukemia (AEL) is characterized by a distinct morphology, mutational spectrum, lack of preclinical models, and poor prognosis. Here, using multiplexed genome editing of mouse hematopoietic stem and progenitor cells and transplant assa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd7d800728c36c24c9c460effedb535
https://doi.org/10.1182/blood.2020009103
https://doi.org/10.1182/blood.2020009103
Autor:
Lindsey Montefiori, Ilaria lacobucci, Amit Budhraja, Jamila Moore, Rebekah Baskin, Rebekah DeVries, Emily Backhaus, Melissa Johnson, Walter Akers, Divyabharathi Chepyala, Cyrus Mehr, Aman Seth, Paul Mead, Joseph Opferman, Charles Mullighan
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S193-S194
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9604581ebfda227074c4d7f77a940c9f
https://doi.org/10.1016/s2152-2650(22)01182-x
https://doi.org/10.1016/s2152-2650(22)01182-x
Autor:
Lindsey Montefiori, Ilaria Iacobucci, Amit Budhraja, Jamila Moore, Rebekah Baskin, Rebekah DeVries, Emily Backhaus, Melissa Johnson, Walter Akers, Divyabharathi Chepyala, Cyrus Mehr, Aman Seth, Paul Mead, Joseph Opferman, Charles Mullighan
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04e9676fdb5b4f305dd74d6ce01af1a6
https://doi.org/10.1016/s2152-2650(22)00713-3
https://doi.org/10.1016/s2152-2650(22)00713-3
Autor:
Kathryn G. Roberts, Lisa J Alcock, Lauren Rowland, Divyabharathi Chepyala, Mark R. Litzow, Elisabeth Paietta, Jamie Jarusiewicz, Baranda S Hansen, Lei Yang, Yunchao Chang, Shondra M. Pruett-Miller, Randolph Larsen, Toshihiko Imamura, Aman Seth, Zoran Rankovic, Koshi Akahane, Dylan Maxwell, Jaeki Min, Shanshan Yu-Chen Bradford, Jun J. Yang, Marisa Actis, Chunxu Qu, Charles G. Mullighan, Stanley Nithianantham, Marcus Fischer, Anand Mayasundari, Hiroaki Goto
Publikováno v:
Blood
CRLF2-rearranged (CRLF2r) acute lymphoblastic leukemia (ALL) accounts for more than half of Philadelphia chromosome-like (Ph-like) ALL and is associated with a poor outcome in children and adults. Overexpression of CRLF2 results in activation of Janu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60f9c122b0bb42ac2efdec667c29170
https://pubmed.ncbi.nlm.nih.gov/34882211
https://pubmed.ncbi.nlm.nih.gov/34882211
Autor:
Stephen P. Hunger, Aman Seth, Laura J. Janke, David Finkelstein, Brian B. Tuch, Yaqi Zhao, Steve Smith, Kevin Ebata, Kathryn G. Roberts, Charles G. Mullighan, Jing Ma
Publikováno v:
Blood. 132:861-865
Publisher's Note: There is a Blood Commentary on this article in this issue.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde76a6a063adf1ee9acc4d64718fa0d
https://doi.org/10.1182/blood-2018-05-849554
https://doi.org/10.1182/blood-2018-05-849554
Autor:
Anitria Cotton, Jinjun Dang, Anang A. Shelat, Jeannie W Lam, Tanja A. Gruber, Shondra M. Pruett-Miller, Jennifer Kamens, Aman Seth, Baranda S Hansen
Publikováno v:
Blood. 138:3446-3446
Pediatric Acute Myeloid Leukemia (AML) is a rare, but deadly cancer. Outcomes over the last 20 years have remained stagnant with an overall 5-year survival rate < 70% and relapse rates around 50%. Further, few new therapies have been successfully int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80d01e33a4236d1c72a0a92a350a92b6
https://doi.org/10.1182/blood-2021-146694
https://doi.org/10.1182/blood-2021-146694
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 18:S199-S200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e81808d9e3a473ef161adca8fe87ed9d
https://doi.org/10.1016/j.clml.2018.07.047
https://doi.org/10.1016/j.clml.2018.07.047