Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Amalia M. Estévez"'
Publikováno v:
Mediterranean Journal of Chemistry. 7:135-144
For the generation of compound libraries for drug discovery a central scaffold containing three exit vectors with defined chirality was devised starting from commercially available tri-O-acetyl-glucal. Surprisingly, the reaction of a 4-O-mesylate wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4e549df7f206dacdac9379803e22e34
https://doi.org/10.13171/mjc72/01809051415-wessel
https://doi.org/10.13171/mjc72/01809051415-wessel
Autor:
Amalia M. Estévez, Ramón J. Estévez, Juan C. Estévez, Marcos A. González González, María Campos
Publikováno v:
The Journal of Organic Chemistry. 83:1543-1550
The first example of a new protocol for the incorporation of γ-amino acids into peptides is reported. It involved a shikimic acid based stereoselective synthesis polyhydroxylated-2-nitromethylcyclohexanecarboxylic acids, which were directly incorpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c306533b6caed7a454d8fd8a90a3f450
https://doi.org/10.1021/acs.joc.7b02671
https://doi.org/10.1021/acs.joc.7b02671
Publikováno v:
Tetrahedron: Asymmetry. 28:837-842
For the generation of DNA-encoded libraries, a central scaffold containing three exit vectors with defined chirality was devised starting from commercially available tri- O -acetyl-glucal. This scaffold may be connected to the DNA barcode at any of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b6c524b4afab604e5821ccc4d4a0768
https://doi.org/10.1016/j.tetasy.2017.04.007
https://doi.org/10.1016/j.tetasy.2017.04.007
Publikováno v:
Tetrahedron. 76:130837
The synthesis of highly functionalized bicyclic and cyclic β-amino acids from β-nitrosugars is reported. Specifically, our strategy for the synthesis of polyhydroxylated cyclopentane β-amino acids via the intramolecular C-alkylation of 6-nitro-2-O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58c590bf832f64dcb8f2ab8d7b679ce
https://doi.org/10.1016/j.tet.2019.130837
https://doi.org/10.1016/j.tet.2019.130837
Autor:
Rosalino Balo, Pablo Thomas, Miguel Alegre, Juan C. Estevez, Raquel G. Soengas, Amalia M. Estévez, Ramón J. Estévez
Publikováno v:
Tetrahedron: Asymmetry. 25:583-590
Herein we report the intramolecular alkylation of nitronates of methyl-5-O-benzyl-3,6-deoxy-6-nitro-β-d-glucofuranoside and methyl-5-O-benzyl-3,6-deoxy-6-nitro-α-d-glucofuranoside into the corresponding 2-oxabicyclo[2.2.1]heptane derivatives. Simil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9c3aff9db772898a442be15ffdb9d28
https://doi.org/10.1016/j.tetasy.2014.03.005
https://doi.org/10.1016/j.tetasy.2014.03.005
Autor:
José M. Otero, Sarah F. Jenkinson, Amalia M. Estévez, Akihide Yoshihara, Ciarán L. Kelly, Mikkel H. S. Marqvorsen, Atsushi Kato, Mark R. Wormald, Zilei Liu, Ramón J. Estévez, John T. Heap, George W. J. Fleet, Ken Izumori
In the search for alternative non‐metabolizable inducers in the l ‐rhamnose promoter system, the synthesis of fifteen 6‐deoxyhexoses from l ‐rhamnose demonstrates the value of synergy between biotechnology and chemistry. The readily available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8a31bedb1719191b777a7292ef32c9
https://nrl.northumbria.ac.uk/id/eprint/43240/1/Manuscript.pdf
https://nrl.northumbria.ac.uk/id/eprint/43240/1/Manuscript.pdf
Autor:
Amalia M. Estévez, Raquel G. Soengas, José M. Otero, Robert J. Nash, George W. J. Fleet, Juan C. Estévez, Ramón J. Estévez
The first stereocontrolled synthesis of (3R,4R,5R,6S)-2,2-bis-(hydroxymethyl)azepane-3,4,5,6-tetraol is described herein. The method involves a novel double Henry reaction of the 3,5-di-O-benzyl-6-deoxy-1,2-O-isopropylidene-6-nitro-α-d-glucofuranose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8e55ab64e13267ad0d4e1491718123
https://doi.org/10.1016/j.tetasy.2008.10.027
https://doi.org/10.1016/j.tetasy.2008.10.027
Autor:
Amalia M. Estévez Reino, Graeme Horne, K. Victoria Booth, George W. J. Fleet, Sarah F. Jenkinson, Ramón J. Estévez
Two carbon chain extensions using a Wittig reaction on both a 1-deoxy ribulose derivative and a C-2-branched erythrose derivative are reported. Subsequent dihydroxylation resulted in the synthesis of C-3 and C-4 methyl-branched sugar lactones, the us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50893476dbf791f23e9037915261a554
https://doi.org/10.1016/j.tetasy.2009.08.029
https://doi.org/10.1016/j.tetasy.2009.08.029
Autor:
Amalia M. Estévez, Ramón J. Estévez
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 12:1443-1454
Shikimic acid, a natural compound is a key intermediate in the biosynthesis of amino acids. Consequently, this derivative is widely present in many plants and has interesting biological properties. But besides the pharmacological relevance of shikimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc713b3b1d49fde923e70538a24304b
https://doi.org/10.2174/138955712803832735
https://doi.org/10.2174/138955712803832735
Indium-mediated allylation and Reformatsky reaction on glyoxylic oximes under ultrasound irradiation
Autor:
Amalia M. Estévez, Raquel G. Soengas
Publikováno v:
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
instname
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
A novel and more convenient method for the indium-promoted allylation of glyoxylic oximes based on the use of ultrasonic waves is reported. A similar procedure was used to develop the first example reported in the literature of an indium-mediated Ref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7e75d7d49b6dab0ec8522ec7fb81d1
https://doi.org/10.1016/j.ultsonch.2011.11.012
https://doi.org/10.1016/j.ultsonch.2011.11.012