Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Amalia Lamana"'
Autor:
Pablo Delgado-Wicke, Sara Fernández de Córdoba-Oñate, Emilia Roy-Vallejo, Estíbaliz Alegría-Carrasco, Diego A. Rodríguez-Serrano, Amalia Lamana, Nuria Montes, Ana Nicolao-Gómez, Rosa Carracedo-Rodríguez, Ana Marcos-Jiménez, Paula Díaz-Fernández, José M. Galván-Román, Laura Rabes-Rodríguez, Marta Sanz-Alba, Jesús Álvarez-Rodríguez, Almudena Villa-Martí, Carlos Rodríguez-Franco, Gonzalo Villapalos-García, Pablo Zubiaur, Francisco Abad-Santos, Ignacio de los Santos, Rosa P. Gomariz, Rosario García-Vicuña, Cecilia Muñoz-Calleja, Isidoro González-Álvaro, Elena Fernández-Ruiz, PREDINMUN-COVID Group
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The characteristics of the host are crucial in the final outcome of COVID-19. Herein, the influence of genetic and clinical variants in COVID-19 severity was investigated in a total of 1350 patients. Twenty-one single nucleotide polymorphism
Externí odkaz:
https://doaj.org/article/0d1fc16c70a649cfaebb526fed6a8fbd
Autor:
Ana Triguero-Martínez, Marisa Pardines, Nuria Montes, Ana María Ortiz, Alba de la Iglesia-Cedeira, Cristina Valero-Martínez, Javier Martín, Isidoro González-Álvaro, Santos Castañeda, Amalia Lamana
Publikováno v:
Life, Vol 14, Iss 9, p 1109 (2024)
The aim of this study was to identify single-nucleotide polymorphisms (SNPs) in bone remodeling-related genes associated with disease severity and bone mineral density (BMD) in early arthritis (EA) patients. For this purpose, the genotyping of 552 SN
Externí odkaz:
https://doaj.org/article/d03648f7504b482b824c9962c2fbbc93
Autor:
Emilia Roy-Vallejo, Sara Fernández De Córdoba-Oñate, Pablo Delgado-Wicke, Ana Triguero-Martínez, Nuria Montes, Rosa Carracedo-Rodríguez, Nelly Zurita-Cruz, Ana Marcos-Jiménez, Amalia Lamana, José María Galván-Román, Gonzalo Villapalos García, Pablo Zubiaur, Marianela Ciudad, Laura Rabes, Marta Sanz, Carlos Rodríguez, Almudena Villa, Jesús Álvarez Rodríguez, Celeste Marcos, Julia Hernando, Paula Díaz-Fernández, Francisco Abad, Ignacio de los Santos, Diego A. Rodríguez Serrano, Rosario García-Vicuña, Carmen Suárez Fernández, Rosa P. Gomariz, Cecilia Muñoz-Calleja, Elena Fernández-Ruiz, Isidoro González-Álvaro, Laura Cardeñoso, the PREDINMUN-COVID Group
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionSARS-CoV-2 viral load has been related to COVID-19 severity. The main aim of this study was to evaluate the relationship between SARS-CoV-2 viremia and SNPs in genes previously studied by our group as predictors of COVID-19 severity.Mater
Externí odkaz:
https://doaj.org/article/8ca2939964894199a76694e0185eb3b7
Autor:
Amalia Lamana, David Castro-Vázquez, Hortensia de la Fuente, Ana Triguero-Martínez, Rebeca Martínez-Hernández, Marcelino Revenga, Raúl Villanueva-Romero, Mar Llamas-Velasco, Pablo Chicharro, Yasmina Juarranz, Mónica Marazuela, Marco Sales-Sanz, Rosario García-Vicuña, Eva Tomero, Isidoro González-Álvaro, Carmen Martínez, Rosa P. Gomariz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8578 (2022)
Few studies have considered immune-mediated inflammatory disorders (IMID) together, which is necessary to adequately understand them given they share common mechanisms. Our goal was to investigate the expression of vasoactive intestinal peptide (VIP)
Externí odkaz:
https://doaj.org/article/55ebef9d4fcb4fb6926c40c9915641e3
Autor:
Ana Triguero-Martínez, Emilia Roy-Vallejo, Nuria Montes, Hortensia de la Fuente, Ana María Ortiz, Santos Castañeda, Isidoro González-Álvaro, Amalia Lamana
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7181 (2022)
Galectin 1 (Gal1) exerts immunomodulatory effects leading to therapeutic effects in autoimmune animal models. Patients with rheumatoid arthritis have been reported to show higher Gal1 serum levels than the healthy population. Our study aimed to find
Externí odkaz:
https://doaj.org/article/9ccc438d35df41d893e6da4c907f19fc
Autor:
Raúl Villanueva-Romero, Alicia Cabrera-Martín, Emigdio Álvarez-Corrales, Mar Carrión, Selene Pérez-García, Amalia Lamana, David Castro-Vázquez, Carmen Martínez, Rosa P. Gomariz, Irene Gutiérrez-Cañas, Yasmina Juarranz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2346 (2022)
Naїve CD4+ T cells, which suffer different polarizing signals during T cell receptor activation, are responsible for an adequate immune response. In this study, we aimed to evaluate the behavior of human CD4+CD45RA+ T cells after in vitro activation
Externí odkaz:
https://doaj.org/article/e70c376334e14e468782113f6a058e63
Autor:
Amalia Lamana, Ricardo Villares, Iria V. Seoane, Nuria Andrés, Pilar Lucas, Paul Emery, Edward M. Vital, Ana Triguero-Martínez, Ana Marquez, Ana M. Ortiz, Robin Maxime, Carmen Martínez, Javier Martín, Rosa P. Gomariz, Frederique Ponchel, Isidoro González-Álvaro, Mario Mellado
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by an autoimmune response in the joints and an exacerbation of cytokine responses. A minority of patients with RA experience spontaneous remission, but most will show moderate/
Externí odkaz:
https://doaj.org/article/4143ce71baa54562bc1f3ffd66bc1924
Autor:
David Castro-Vazquez, Amalia Lamana, Paula Arribas-Castaño, Irene Gutiérrez-Cañas, Raúl Villanueva-Romero, Selene Pérez-García, Carmen Martínez, Yasmina Juarranz, Sara Fernández de Córdoba, Isidoro González-Álvaro, Rosa P. Gomariz, Mar Carrión
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1880 (2021)
We aimed to evaluate the direct action of VIP on crucial molecules involved in human osteoclast differentiation and function. We also investigated the relationship between VIP serum levels and bone remodeling mediators in early arthritis patients. Th
Externí odkaz:
https://doaj.org/article/36f5abb13b0546379d67b6e2ed6f2879
Autor:
Rosa P. Gomariz, Yasmina Juarranz, Mar Carrión, Selene Pérez-García, Raúl Villanueva-Romero, Isidoro González-Álvaro, Irene Gutiérrez-Cañas, Amalia Lamana, Carmen Martínez
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
The axis comprised by the Vasoactive Intestinal Peptide (VIP) and its G protein-coupled receptors (GPCRs), VPAC1, and VPAC2, belong to the B1 family and signal through Gs or Gq proteins. VPAC receptors seem to preferentially interact with Gs in infla
Externí odkaz:
https://doaj.org/article/be5d61726b194778b5dd6219f00f9545
Autor:
Raúl Villanueva-Romero, Amalia Lamana, Marissa Flores-Santamaría, Mar Carrión, Selene Pérez-García, Ana Triguero-Martínez, Eva Tomero, Gabriel Criado, José L. Pablos, Isidoro González-Álvaro, Carmen Martínez, Yasmina Juarranz, Rosa P. Gomariz, Irene Gutiérrez-Cañas
Publikováno v:
Cells, Vol 9, Iss 12, p 2592 (2020)
Pro-inflammatory CD4+CD28− T cells are characteristic of immunosenescence, but also of several autoimmune/inflammatory diseases. Vasoactive intestinal peptide (VIP) acts as an anti-inflammatory and immunomodulatory mediator on these cells. Our obje
Externí odkaz:
https://doaj.org/article/e98da2cb91594aed81e1a2d8365db4ea