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pro vyhledávání: '"Amalia F. Tsolakidou"'
Autor:
Constantine E. Sekeris, C. Troungos, George Trikkas, Amalia F. Tsolakidou, Paraskevi Moutsatsou
Publikováno v:
Molecular Psychiatry 5:2 (Mar2000): 196-202
Molecular Psychiatry 5:2(Mar2000):196-202
Molecular Psychiatry 5:2(Mar2000):196-202
The periodically hyperactive hypothalamic-pituitary-adrenal (HPA) axis in bipolar affective disorders, as well as the reported changes in the binding characteristics of the glucocorticoid receptor (GR), suggest the possible involvement of the GR in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448daa1dc6456eb8221981565455db86
http://helios-eie.ekt.gr/EIE/handle/10442/7328
http://helios-eie.ekt.gr/EIE/handle/10442/7328
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 349(1-2)
Background In Alzheimer's disease (AD), the hypothalamic–pituitary–adrenal (HPA) axis is hyperactive and the sensitivity to dexamethasone is decreased, suggesting a possible involvement of glucocorticoid receptor alpha (GRα) defects in the aetio
Publikováno v:
Clinical biochemistry. 36(4)
Objectives In a previous publication, we had presented a sensitive method to detect mutations of the segment of the human glucocorticoid receptor alpha (hGRα) gene encoding the ligand binding domain (LBD) and part of the DNA binding domain (DBD) of
Publikováno v:
Journal of biochemical and biophysical methods. 51(3)
Mutations in the hormone-binding domain of the human glucocorticoid receptor alpha (hGRα) gene have been detected in a variety of glucocorticoid resistance syndromes. Using the denaturing gradient gel electrophoresis technique, we developed a sensit