Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amala Bhagwat"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Drug resistance is an increasing problem for the treatment of tuberculosis. The prevalence of clinical isolates with pre-existing resistance needs to be considered in any drug discovery program. Non-specific mechanisms of resistance such as increased
Externí odkaz:
https://doaj.org/article/6657a959d46b4a57a1319145f9823b04
Publikováno v:
bioRxiv
Indolcarboxamides are a promising series of anti-tubercular agents which targetMycobacterium tuberculosisMmpL3, the exporter of trehalose monomycolate, a key cell wall component. We determined the kill kinetics of the lead indolcarboxamide NITD-349 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b361e1abf20325f2c8dbd5a78fa71155
https://europepmc.org/articles/PMC9980077/
https://europepmc.org/articles/PMC9980077/
Publikováno v:
Journal of Biotechnology. 330:27-34
The bacteriolysin lysostaphin (Lst) and endolysin PlyPH are potent modular lytic enzymes with activity against clinically-relevant Gram-positive Staphylococcus aureus and Bacillus cereus, respectively. Both enzymes possess an N-terminal catalytic dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe315da08abc74aa1baae0af91d5d13
https://doi.org/10.1016/j.jbiotec.2021.02.010
https://doi.org/10.1016/j.jbiotec.2021.02.010
Publikováno v:
Frontiers in cellular and infection microbiology. 12
Drug resistance is an increasing problem for the treatment of tuberculosis. The prevalence of clinical isolates with pre-existing resistance needs to be considered in any drug discovery program. Non-specific mechanisms of resistance such as increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fbfcf70d2cabad19fd7bea135c5d3ea
https://pubmed.ncbi.nlm.nih.gov/36159638
https://pubmed.ncbi.nlm.nih.gov/36159638
Publikováno v:
Applied microbiology and biotechnology. 104(21)
In light of emerging antibiotic resistance, bacterial cell wall lytic enzymes are promising antimicrobial agents that degrade bacterial peptidoglycan while specifically recognizing the target bacterium. The efficacy of lytic enzymes against several m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540212bc0143a15c5fb8fb0370722b5a
https://pubmed.ncbi.nlm.nih.gov/32945900
https://pubmed.ncbi.nlm.nih.gov/32945900
Publikováno v:
Applied microbiology and biotechnology. 103(17)
The role that the complex microbial communities play in human and environmental health cannot be understated. The increased information about community complexity, as well as the overuse of broad-spectrum antibiotics, suggest that new approaches to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5029359c846c9944537ceae20f676b4b
https://pubmed.ncbi.nlm.nih.gov/31203418
https://pubmed.ncbi.nlm.nih.gov/31203418