Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Amal Wanigatunga"'
Autor:
William Earle, Katharine Rainer, Lawrence J Appel, Edgar R Miller, Erin D Michos, Jennifer Schrack, Amal Wanigatunga, Christine Mitchell, Heather Rebuck, Robert H Christenson, Stephen P Juraschek
Publikováno v:
Circulation. 147
Background: In observational studies, older adults with insufficient or deficient serum vitamin D levels are at higher risk of cardiovascular disease (CVD), but randomized trials have failed to demonstrate reduction in CVD risk from vitamin D supplem
Autor:
Yurun Cai, Jennifer A. Schrack, Yuri Agrawal, Nicole M. Armstrong, Amal Wanigatunga, Melissa Kitner-Triolo, Abhay Moghekar, Luigi Ferrucci, Eleanor M. Simonsick, Susan M. Resnick, Alden L. Gross
Publikováno v:
medRxiv
ObjectiveDue to the long prodromal period for dementia pathology, approaches are needed to detect cases before clinically recognizable symptoms are apparent, by which time it is likely too late to intervene. This study contrasted two theoretically-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d5057b5f30a2e95c4c414abdfc60d8
https://doi.org/10.1101/2023.02.04.23285477
https://doi.org/10.1101/2023.02.04.23285477
Autor:
Aldis H Petriceks, Lawrence J Appel, Edgar R Miller, Christine Mitchell, Jennifer Schrack, Ken J Mukamal, Lewis Lipsitz, Amal Wanigatunga, Tim B Plante, Erin D Michos, Yurun Cai, Stephen P Juraschek
Publikováno v:
Hypertension. 79
Background: There is inconsistent evidence on the optimal time after standing to assess orthostatic hypotension (OH). Objectives: To characterize the timing of OH after standing in older adults and the fall risk associated with OH at specific times.
Autor:
Jennifer Schrack, Venus Chiu, Amal Wanigatunga, Daniela Sotres-Alvarez, Shoshana Ballew, Matthew Allison, Robert Kaplan, Kunihiro Matsushita
Publikováno v:
Innovation in Aging. 6:330-331
The benefits of routine engagement in physical activity (PA) on vascular health are well established; lesser known is whether vascular health associates with accelerometry-based daily patterns of PA in mid-to-late life. Using linear regression models
Autor:
Amal Wanigatunga, Xiaomeng Chen, Francesca Marino, Eleanor Simonsick, Luigi Ferrucci, Jennifer Schrack
Publikováno v:
Innovation in Aging. 6:369-370
This study hypothesized that perceived fatigability, fatigue standardized to walking, would better discriminate mortality risk than general fatigue symptoms. We leveraged perceived fatigability, self-reported tiredness, self-reported low energy and m
Autor:
Fangyu Liu, Jennifer Schrack, Sarah Wanigatunga, Jill Rabinowitz, Linchen He, Amal Wanigatunga, Eleanor Simonsick, Adam Spira
Publikováno v:
Innovation in Aging. 6:331-331
Researchers often prefer different accelerometers for measurement of sleep and physical activity (PA) in older adults, but wearing multiple accelerometers increases costs and participant burden. We tested the hypothesis that the Actiwatch-2, commonly
Autor:
Francesca Marino, Fangyu Liu, Eleanor Simonsick, Qu Tian, Jennifer Deal, Amal Wanigatunga, Susan Resnick, Jennifer Schrack
Publikováno v:
Innovation in Aging. 6:331-331
β-amyloid is a hallmark of Alzheimer’s disease and can be measured in vivo by PET imaging. Whether PiB+ (elevated β-amyloid) individuals exhibit distinct physical activity patterns throughout the day (i.e., activity amount or fragmentation) is un
Autor:
Amal Wanigatunga, Chenxin Tian, Yang An, Yurun Cai, Alden Gross, Eleanor Simonsick, Jennifer Schrack, Yuri Agrawal
Publikováno v:
Innovation in Aging. 6:690-690
Age-related sensory impairment, such as loss in vision or hearing, have been linked to poor brain health. Yet, the relationship between co-occurring sensory impairments and brain volumes remains unclear. We used cross-sectional sensory and brain imag
Autor:
Amal Wanigatunga, Francesca Marino, Fangyu Liu, Eleanor Simonsick, Qu Tian, Jennifer Deal, Susan Resnick, Jennifer Schrack
Publikováno v:
Innovation in Aging. 6:331-331
The Apolipoprotein-ε4 (APOE-ε4) genotype is associated with earlier onset and greater risk of β-amyloid deposition, but whether APOE-ε4 status is associated with physical activity amount or fragmentation remains unclear. In 563 BLSA participants
Autor:
Jennifer Schrack, Amal Wanigatunga
Publikováno v:
Innovation in Aging. 6:330-330
Physical activity and sleep are well-established predictors of health and longevity with aging. Wrist accelerometers, that produce high-frequency time series data, capture multiple aspects of daily physical activity and sleep 24-hours/day. Historical