Výsledky vyhledávání - "Amal T. Elhaw"

Abstract A034: Orchestrated expression of the atypical Rho-GTPase, RHOV, in response to matrix detachment of ovarian cancer cells

Autor: Amal T. Elhaw, Yeon Soo Kim, Zaineb Javed, Priscilla Tang, Weihua Pan, Nadine Hempel

Publikováno v: Cancer Research. 83:A034-A034

Ovarian cancer (OVCA) metastasis occurs through the process of transcoelomic spread, where cells disseminate into the peritoneal fluid and form multi-cellular aggregates (MCA) that mediate Anchorage-Independent (A-I) survival and invasion of the peri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f53480ab882a67dd8d179d9ba8dc115
https://doi.org/10.1158/1538-7445.metastasis22-a034

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HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage independence

Autor: Zaineb Javed, Karthikeyan Mythreye, Yeon Soo Kim, Nadine Hempel, Priscilla W. Tang, Jaclyn E. Welles, Scot R. Kimball, Amal T. Elhaw

During metastasis, cancer cells must adapt to survive a loss of anchorage and evade anoikis. An important pro-survival adaptation is the ability of metastatic tumor cells to increase their antioxidant capacity and restore cellular redox balance. Alth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ac4ff397d52173cbfa2788a88127e19
https://doi.org/10.1101/2021.02.19.432010

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Abstract 2445: Orchestrated expression of the atypical Rho-GTPase RHOV mediates multicellular aggregate formation in ovarian cancer

Autor: Amal T. Elhaw, Yeon Soo Kim, Zaineb Javed, Priscilla Tang, Weihua Pan, Nadine Hempel

Publikováno v: Cancer Research. 82:2445-2445

Transcoelomic spread is a major mode of ovarian cancer (OVCA) metastasis, where cells disseminate into the peritoneal ascites fluid, evade anoikis, and form multi-cellular aggregates (MCAs) that mediate anchorage-independent (a-i) survival and invasi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d31ab26652439f24bd355eeeb4b6e1ef
https://doi.org/10.1158/1538-7445.am2022-2445

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Abstract 128: SIRT3 supports anchorage-independent survival of ovarian cancer cells

Autor: Priscilla Tang, Yeon Soo Kim, Piyushi Gupta-Vallur, Amal T. Elhaw, Zaineb Javed, Weihua Pan, Nadine Hempel

Publikováno v: Cancer Research. 82:128-128

Metabolic changes during tumor progression have numerous consequences on cancer cells, including an increased risk of cell death due to production of reactive oxygen species (ROS). Antioxidant defense adaptations thus accompany metabolic alterations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5291147295653d5336bcac1aa9ca59d
https://doi.org/10.1158/1538-7445.am2022-128

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