Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Amal O Amer"'
Autor:
Kyle Jablonski, Nicholas A Young, Caitlin Henry, Kyle Caution, Anuradha Kalyanasundaram, Ifeoma Okafor, Peter Harb, Emmy Schwarz, Paul Consiglio, Chris M Cirimotich, Anna Bratasz, Anasuya Sarkar, Amal O Amer, Wael N Jarjour, Naomi Schlesinger
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0237520 (2020)
ObjectivesGout is the most prevalent inflammatory arthritis. To study the effects of regular physical activity and exercise intensity on inflammation and clinical outcome, we examined inflammatory pathogenesis in an acute model of murine gout and ana
Externí odkaz:
https://doaj.org/article/81b2378e9ff54aebbab0ff7b32af637d
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0213092 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0096681.].
Externí odkaz:
https://doaj.org/article/1b33dbb4d5124325bbbf517c425f5b5f
Autor:
Chandra L Shrestha, Kaivon D Assani, Hannah Rinehardt, Florentina Albastroiu, Shuzhong Zhang, Richard Shell, Amal O Amer, Larry S Schlesinger, Benjamin T Kopp
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186169 (2017)
Members of the Burkholderia cepacia complex are virulent, multi-drug resistant pathogens that survive and replicate intracellularly in patients with cystic fibrosis (CF). We have discovered that B. cenocepacia cannot be cleared from CF macrophages du
Externí odkaz:
https://doaj.org/article/04f3c4965e0c4d69b8e9c95c8806aa5b
Autor:
Kathrin eKrause, Amal O Amer
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Legionella pneumophila remains a major health concern, especially for hospitalized patients. L. pneumophila in the environment can survive extracellular or as protozoan parasite within amoeba. After human infection it efficiently replicates in alveol
Externí odkaz:
https://doaj.org/article/fb8c7649fe9f422cbe7649d1ada81a3b
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146410 (2016)
L. pneumophila is the causative agent of Legionnaires' disease, a human illness characterized by severe pneumonia. In contrast to those derived from humans, macrophages derived from most mouse strains restrict L. pneumophila replication. The restrict
Externí odkaz:
https://doaj.org/article/fac2c9e81834499082e9c5e806d602d1
Autor:
Samuel Speaks, Matthew I. McFadden, Ashley Zani, Abigail Solstad, Steve Leumi, Jack E. Roettger, Adam D. Kenney, Hannah Bone, Lizhi Zhang, Parker J. Denz, Adrian C. Eddy, Amal O. Amer, Richard T. Robinson, Chuanxi Cai, Jianjie Ma, Emily A. Hemann, Adriana Forero, Jacob S. Yount
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Influenza virus activates cellular inflammasome pathways, which can be both beneficial and detrimental to infection outcomes. Here, we investigate the function of the inflammasome-activated, pore-forming protein gasdermin D (GSDMD) during in
Externí odkaz:
https://doaj.org/article/1bdb4d643c5340eaab89b6eb41184ba9
Autor:
Yongqun Oliver eHe, Amal O Amer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Externí odkaz:
https://doaj.org/article/f7be3488cdc543bf8e0a3292aa234eb6
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96681 (2014)
Burkholderia cenocepacia is a virulent pathogen that causes significant morbidity and mortality in patients with cystic fibrosis (CF), survives intracellularly in macrophages, and uniquely causes systemic infections in CF. Autophagy is a physiologic
Externí odkaz:
https://doaj.org/article/8c4e9b7daa2a4fe3be3664ed2390ae7d
Autor:
Kylene P. Daily, Asmaa Badr, Mostafa Eltobgy, Shady Estfanous, Owen Whitham, Michelle H. Tan, Cierra Carafice, Kathrin Krause, Andrew McNamara, Kaitlin Hamilton, Samuel Houle, Spandan Gupta, Gauruv A. Gupta, Shruthi Madhu, Julie Fitzgerald, Abbey A. Saadey, Brooke Laster, Pearlly Yan, Amy Webb, Xiaoli Zhang, Maciej Pietrzak, Olga N. Kokiko-Cochran, Hazem E. Ghoneim, Amal O. Amer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Alzheimer’s disease (AD) is the sixth leading cause of death in the USA. It is established that neuroinflammation contributes to the synaptic loss, neuronal death, and symptomatic decline of AD patients. Accumulating evidence suggests a cr
Externí odkaz:
https://doaj.org/article/e9004d48993349bc9f739f58c680a79a