Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Amal M. El-Naggar"'
Autor:
Poul H. Sorensen, Dimiter S. Dimitrov, Olivier Delattre, Gregg B. Morin, Li-Yan Xu, Rimas J. Orentas, Ramon I. Klein Geltink, Seth J. Parker, Mads Daugaard, Anne Steino, Amy Li, Sonia H.Y. Kung, Jonathan K.M. Lim, Sofya Langman, Anne-Chloe Dhez, Colin A. Hammond, Renata Scopim-Ribeiro, Taras Shyp, Shane Colborne, Htoo Zarni Oo, Michael M. Lizardo, Maj Sofie Ørum-Madsen, Xiaojun Li, Gian Luca Negri, Alberto Delaidelli, Anna Prudova, Hongwei Cheng, Amal M. El-Naggar, Didier Surdez, Jian-Zhong He, Wei Li, Christopher S. Hughes, Hai-Feng Zhang
Supplementary Data from Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e6166f1c594b2194af8072175d86fe
https://doi.org/10.1158/2159-8290.22540877
https://doi.org/10.1158/2159-8290.22540877
Autor:
Poul H. Sorensen, Dimiter S. Dimitrov, Olivier Delattre, Gregg B. Morin, Li-Yan Xu, Rimas J. Orentas, Ramon I. Klein Geltink, Seth J. Parker, Mads Daugaard, Anne Steino, Amy Li, Sonia H.Y. Kung, Jonathan K.M. Lim, Sofya Langman, Anne-Chloe Dhez, Colin A. Hammond, Renata Scopim-Ribeiro, Taras Shyp, Shane Colborne, Htoo Zarni Oo, Michael M. Lizardo, Maj Sofie Ørum-Madsen, Xiaojun Li, Gian Luca Negri, Alberto Delaidelli, Anna Prudova, Hongwei Cheng, Amal M. El-Naggar, Didier Surdez, Jian-Zhong He, Wei Li, Christopher S. Hughes, Hai-Feng Zhang
Supplementary Table from Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5f6db3565e8f004bc82ed28ead0aca
https://doi.org/10.1158/2159-8290.22540874.v1
https://doi.org/10.1158/2159-8290.22540874.v1
Autor:
Poul H. Sorensen, Dimiter S. Dimitrov, Olivier Delattre, Gregg B. Morin, Li-Yan Xu, Rimas J. Orentas, Ramon I. Klein Geltink, Seth J. Parker, Mads Daugaard, Anne Steino, Amy Li, Sonia H.Y. Kung, Jonathan K.M. Lim, Sofya Langman, Anne-Chloe Dhez, Colin A. Hammond, Renata Scopim-Ribeiro, Taras Shyp, Shane Colborne, Htoo Zarni Oo, Michael M. Lizardo, Maj Sofie Ørum-Madsen, Xiaojun Li, Gian Luca Negri, Alberto Delaidelli, Anna Prudova, Hongwei Cheng, Amal M. El-Naggar, Didier Surdez, Jian-Zhong He, Wei Li, Christopher S. Hughes, Hai-Feng Zhang
Cancer cells must overcome anoikis (detachment-induced death) to successfully metastasize. Using proteomic screens, we found that distinct oncoproteins upregulate IL1 receptor accessory protein (IL1RAP) to suppress anoikis. IL1RAP is directly induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8bdb1c5f12ead9674106bc25ce091c7
https://doi.org/10.1158/2159-8290.c.6549488.v1
https://doi.org/10.1158/2159-8290.c.6549488.v1
Autor:
Josef M. Penninger, Poul H. Sorensen, Astrid Hagelkruys, Mads Daugaard, Fumiyo Ikeda, Jeffrey M. Trent, David A. Williams, Maria Novatchkova, Domagoj Cikes, David Hoffmann, Iris Uribesalgo, Shuan Rao, Bianca V. Gapp, Anoop M. Kavirayani, Davide Tortora, Roberto Nitsch, Carlos Gomez-Diaz, Stefan Mereiter, Amal M. El-Naggar, Alexandra Leopoldi, Gian Luca Negri, Luigi Tortola, Melanie Kogler
Supplementary Figures (Fig.S1-S4) and Supplementary Materials and Methods. Supplementary Figure S1. Loss of Hace1 results in increased lung tumorigenesis independent of RIPK3. Supplementary Figure S2. Analysis of RAC, NRF2 and 4HNE expression. Supple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c762c3f76b3a9ec23d9864c4312b504
https://doi.org/10.1158/0008-5472.22423049
https://doi.org/10.1158/0008-5472.22423049
Autor:
Josef M. Penninger, Poul H. Sorensen, Astrid Hagelkruys, Mads Daugaard, Fumiyo Ikeda, Jeffrey M. Trent, David A. Williams, Maria Novatchkova, Domagoj Cikes, David Hoffmann, Iris Uribesalgo, Shuan Rao, Bianca V. Gapp, Anoop M. Kavirayani, Davide Tortora, Roberto Nitsch, Carlos Gomez-Diaz, Stefan Mereiter, Amal M. El-Naggar, Alexandra Leopoldi, Gian Luca Negri, Luigi Tortola, Melanie Kogler
HACE1 is an E3 ubiquitin ligase with important roles in tumor biology and tissue homeostasis. Loss or mutation of HACE1 has been associated with the occurrence of a variety of neoplasms, but the underlying mechanisms have not been defined yet. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47b8bff96ba19bbd6b416abc888a345e
https://doi.org/10.1158/0008-5472.c.6511412.v1
https://doi.org/10.1158/0008-5472.c.6511412.v1
Autor:
Josef M. Penninger, Poul H. Sorensen, Astrid Hagelkruys, Mads Daugaard, Fumiyo Ikeda, Jeffrey M. Trent, David A. Williams, Maria Novatchkova, Domagoj Cikes, David Hoffmann, Iris Uribesalgo, Shuan Rao, Bianca V. Gapp, Anoop M. Kavirayani, Davide Tortora, Roberto Nitsch, Carlos Gomez-Diaz, Stefan Mereiter, Amal M. El-Naggar, Alexandra Leopoldi, Gian Luca Negri, Luigi Tortola, Melanie Kogler
HACE1 mutational landscape in human cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c84c881ea494266d44fc4c8e39ae547
https://doi.org/10.1158/0008-5472.22423046
https://doi.org/10.1158/0008-5472.22423046
Abstract 4967: Investigating the therapeutic efficacy of EO3001 in clear cell carcinoma of the ovary
Autor:
Amal M. EL-Naggar, Yuchen Ding, Lucy Li, Forouh Kalantari, Jeffrey Bacha, Dennis Brown, David Huntsman
Publikováno v:
Cancer Research. 83:4967-4967
Introduction Clear cell ovarian cancer (CCC) accounts for 5-11% of ovarian cancers in North America with a higher frequency reported in cohorts from Japan. CCC usually arises directly from endometriosis, which is associated with oxidative stress. The
Autor:
Amal M. El-Naggar, Yuchen Ding, Genny Trigo-Gonzalez, Lucy Li, Shary Chen, Busra Turgu, Forouh Kalantari, Rodrigo Vallejos, Kiran Parmar, Cindy Shen, Gian Luca Negri, Paul Yong, Gregg Morin, David G. Huntsman
Publikováno v:
Cancer Research. 83:2482-2482
Introduction: Clear cell carcinoma of the ovary (CCC) is the 2nd most common ovarian cancer and is histologically and clinically distinct from other subtypes. Late stage CCC have a worse prognosis than other ovarian cancer histotypes as they are inhe
Autor:
Marina Ayres Pereira, Anders Riis Kristensen, Htoo Zarni Oo, Mette Ø. Agerbæk, Paul M. Grandgenett, Michael A. Hollingsworth, Peter Johannes Holst, Poul H. Sorensen, Amal M. El-Naggar, Maj Sofie Ørum-Madsen, Ali Salanti, Sherry Lee, Thor G. Theander, Mads Daugaard, Thomas Mandel Clausen, Jean L. Grem, Nader Al Nakouzi
Publikováno v:
Molecular Cancer Research. 14:1288-1299
Many tumors express proteoglycans modified with oncofetal chondroitin sulfate glycosaminoglycan chains (ofCS), which are normally restricted to the placenta. However, the role of ofCS in cancer is largely unknown. The function of ofCS in cancer was a
Autor:
Poul H. Sorensen, Gian Luca Negri, Alberto Delaidelli, Brian Cho, Sean Minaker, Mariarita Santi, John M. Maris, Amal M. El Naggar, Stephen Yip, Juliette Hukin
BACKGROUND/OBJECTIVES: Brain tumors represent the most common and aggressive pediatric cancer type, underscoring a dire need for novel therapeutic approaches. Tumors are continually exposed to acute changes in their microenvironment, including oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993d14bcedfd8829c60c68850050fadc
https://europepmc.org/articles/PMC6217157/
https://europepmc.org/articles/PMC6217157/