Zobrazeno 1 - 10 of 35 pro vyhledávání: '"Amal F Dawood"'
1
Akademický článek
Vanillylacetone attenuates cadmium chloride-induced hippocampal damage and memory loss through up-regulation of nuclear factor erythroid 2-related factor 2 gene and protein expression
Autor: Fahaid H AL-Hashem, Salah O Bashir, Amal F Dawood, Moutasem S Aboonq, Ismaeel Bin-Jaliah, Abdulaiziz M Al-Garni, Mohamed D Morsy
Publikováno v: Neural Regeneration Research, Vol 19, Iss 12, Pp 2750-2759 (2024)
Memory loss and dementia are major public health concerns with a substantial economic burden. Oxidative stress has been shown to play a crucial role in the pathophysiology of hippocampal damage-induced memory impairment. To investigate whether the an
Externí odkaz: https://doaj.org/article/27184162a4d54730933ab4162474e116
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2
Akademický článek
Antioxidant Activity of Vitamin C against LPS-Induced Septic Cardiomyopathy by Down-Regulation of Oxidative Stress and Inflammation
Autor: Ayed A. Shati, Mohamed Samir A. Zaki, Youssef A. Alqahtani, Saleh M. Al-Qahtani, Mohamed A. Haidara, Amal F. Dawood, Asmaa M. AlMohanna, Mahmoud H. El-Bidawy, Muhammad Alaa Eldeen, Refaat A. Eid
Publikováno v: Current Issues in Molecular Biology, Vol 44, Iss 5, Pp 2387-2400 (2022)
In severe cases of sepsis, endotoxin-induced cardiomyopathy can cause major damage to the heart. This study was designed to see if Vitamin C (Vit C) could prevent lipopolysaccharide-induced heart damage. Eighteen Sprague Dawley male rats (n = 6) were
Externí odkaz: https://doaj.org/article/926efea9cb484b8d8344e74591c8d132
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3
Akademický článek
Metformin Is Associated with the Inhibition of Renal Artery AT1R/ET-1/iNOS Axis in a Rat Model of Diabetic Nephropathy with Suppression of Inflammation and Oxidative Stress and Kidney Injury
Autor: Amal F. Dawood, Amro Maarouf, Norah M. Alzamil, Maha A. Momenah, Ayed A. Shati, Nervana M. Bayoumy, Samaa S. Kamar, Mohamed A. Haidara, Asmaa M. ShamsEldeen, Hanaa Z. Yassin, Peter W. Hewett, Bahjat Al-Ani
Publikováno v: Biomedicines, Vol 10, Iss 7, p 1644 (2022)
Diabetes is the most common cause of end-stage renal disease, also called kidney failure. The link between the renal artery receptor angiotensin II type I (AT1R) and endothelin-1 (ET-1), involved in vasoconstriction, oxidative stress, inflammation an
Externí odkaz: https://doaj.org/article/600eb28520a941abbebb24d26f02891a
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4
Akademický článek
MiR-155 Dysregulation Is Associated with the Augmentation of ROS/p53 Axis of Fibrosis in Thioacetamide-Induced Hepatotoxicity and Is Protected by Resveratrol
Autor: Amal F. Dawood, Suliman Al Humayed, Maha A. Momenah, Mohamed El-Sherbiny, Hend Ashour, Samaa S. Kamar, Asmaa M. ShamsEldeen, Mohamed A. Haidara, Bahjat Al-Ani, Hasnaa A. Ebrahim
Publikováno v: Diagnostics, Vol 12, Iss 7, p 1762 (2022)
Liver fibrosis is a hallmark of thioacetamide (TAA) intoxications. MicroRNAs (miRs), such as miR-155, have been implied in the pathogenesis of liver disease, and regulated by the antioxidant and anti-inflammatory compound resveratrol (RES). The link
Externí odkaz: https://doaj.org/article/33bd274a9576411487c0ff5eaa253473
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6
Akademický článek
Metformin Protects against Diabetic Cardiomyopathy: An Association between Desmin–Sarcomere Injury and the iNOS/mTOR/TIMP-1 Fibrosis Axis
Autor: Amal F. Dawood, Norah M. Alzamil, Peter W. Hewett, Maha A. Momenah, Mohammad Dallak, Samaa S. Kamar, Dina H. Abdel Kader, Hanaa Yassin, Mohamed A. Haidara, Amro Maarouf, Bahjat Al-Ani
Publikováno v: Biomedicines, Vol 10, Iss 5, p 984 (2022)
The intermediate filament protein desmin is essential for maintaining the structural integrity of sarcomeres, the fundamental unit of cardiac muscle. Diabetes mellitus (DM) can cause desmin to become dysregulated, following episodes of nitrosative st
Externí odkaz: https://doaj.org/article/dcc02c6c30bc4f4f944e8136ff856c0a
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8
Akademický článek
Potential Protective Effect of Vitamin C on Qunalphos-Induced Cardiac Toxicity: Histological and Tissue Biomarker Assay
Autor: Ayed A. Shati, Mohamed Samir A. Zaki, Youssef A. Alqahtani, Mohamed A. Haidara, Mubarak Al-Shraim, Amal F. Dawood, Refaat A. Eid
Publikováno v: Biomedicines, Vol 10, Iss 1, p 39 (2021)
Insecticides and toxicants abound in nature, posing a health risk to humans. Concurrent exposure to many environmental contaminants has been demonstrated to harm myocardial performance and reduce cardiac oxidative stress. The purpose of this research
Externí odkaz: https://doaj.org/article/854bd2c9b14049b8b6488453daf67ef9
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