Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Amal Abdel Haleem Eissa"'
Autor:
Gary A. Piazza, Marwa Saeed Hany, Bernard D. Gary, Heather N. Tinsley, Ashraf H. Abadi, Amal Abdel Haleem Eissa, Shimaa Awadain Elsharif
Publikováno v:
Chemical and Pharmaceutical Bulletin. 61:405-410
Analogues with the scaffolds of 3-cyano-4-alkoxyphenyl-6-bromoaryl-2-pyridone and 2-amino-3-cyano-4-alkoxyphenyl-6-bromoarylpyridine were synthesized. Cyclization of the 2-amino derivatives with formic acid and formamide gave the corresponding pyrido
Publikováno v:
Chemicalpharmaceutical bulletin. 51(7)
Several 1,3,4-trisubstituted pyrazole derivatives were synthesized and screened for their cytotoxic effect in a primary 3 tumor cell line test at 10(-4) M drug concentration. Compounds 19 and 20 reduced the growth of one or more of these cell lines t