Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Amal, Yussuf"'
Autor:
Edwin S. Iversen, Gary Lipton, Steven N. Hart, Kun Y. Lee, Chunling Hu, Eric C. Polley, Tina Pesaran, Amal Yussuf, Holly LaDuca, Elizabeth Chao, Rachid Karam, David E. Goldgar, Fergus J. Couch, Alvaro N. A. Monteiro
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract Loss-of-function variants in the BRCA1 and BRCA2 susceptibility genes predispose carriers to breast and/or ovarian cancer. The use of germline testing panels containing these genes has grown dramatically, but the interpretation of the result
Externí odkaz:
https://doaj.org/article/a9b402e69faa4cd5a657f04f06fd7feb
Autor:
Brittany L. Bychkovsky, Min-Tzu Lo, Amal Yussuf, Carrie Horton, Parichehr Hemyari, Holly LaDuca, Judy E. Garber, Rochelle Scheib, Huma Q. Rana
Publikováno v:
Breast Cancer Research and Treatment. 200:63-72
Purpose Herein, we report the frequency and distribution of germline pathogenic variants (PVs) among females with breast cancer (BC) and at least one other non-BC who underwent multi-gene panel testing (MGPT). Among females with PVs diagnosed first w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09fd07cb1c3e39008656dfcb74df7cc4
https://doi.org/10.1007/s10549-023-06870-x
https://doi.org/10.1007/s10549-023-06870-x
Autor:
Matthew B. Yurgelun, Hajime Uno, C. Sloane Furniss, Chinedu Ukaegbu, Miki Horiguchi, Amal Yussuf, Holly LaDuca, Anu Chittenden, Judy E. Garber, Sapna Syngal
Publikováno v:
Journal of Clinical Oncology. 40:4083-4094
PURPOSE With the availability of multigene panel testing (MGPT) for hereditary cancer risk assessment, clinicians need to assess the likelihood of pathogenic germline variants (PGVs) across numerous genes in parallel. This study's aim was to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b58c2133d9d7ef86b1c05a88cb5b8c1
https://doi.org/10.1200/jco.22.00120
https://doi.org/10.1200/jco.22.00120
Autor:
Brittany L. Bychkovsky, Min-Tzu Lo, Amal Yussuf, Carrie Horton, Parichehr Hemyari, Holly LaDuca, Judy E. Garber, Huma Q. Rana
Publikováno v:
Cancer Research. 82:P2-09
Background: Among females with breast cancer, multiple primary cancers (MPCs) are a hallmark of cancer predisposition syndromes. Herein we report the frequency of germline pathogenic/likely pathogenic variants (PVs) among females with breast cancer (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd1e0bbd473c7e072b0b45d674fc0591
https://doi.org/10.1158/1538-7445.sabcs21-p2-09-03
https://doi.org/10.1158/1538-7445.sabcs21-p2-09-03
Autor:
Tina Pesaran, Jeffrey N. Weitzel, Clarice R. Weinberg, Chi Gao, Susan L. Neuhausen, Eric C. Polley, Alpa V. Patel, Christopher A. Haiman, Christine B. Ambrosone, Celine M. Vachon, Hongyan Huang, Sara Lindstrom, Julie R. Palmer, Esther M. John, Jill S. Dolinsky, Leslie Bernstein, Rohan Gnanaolivu, Allison W. Kurian, Steven N. Hart, Holly LaDuca, Hoda Anton-Culver, Janet E. Olson, Chunling Hu, Amal Yussuf, Song Yao, Nicole L. Larson, Peter Kraft, Jie Na, Fergus J. Couch, Nicholas J. Boddicker, Elena Martinez, Amy Trentham-Dietz, Siddhartha Yadav, Paul W. Auer, Dale R Sandler, Elizabeth C. Chao, Susan M. Domchek, Rachid Karam, Katherine L. Nathanson, James V. Lacey, Jack A. Taylor, David E. Goldgar
Publikováno v:
J Clin Oncol
PURPOSE To determine the contribution of germline pathogenic variants (PVs) in hereditary cancer testing panel genes to invasive lobular carcinoma (ILC) of the breast. MATERIALS AND METHODS The study included 2,999 women with ILC from a population-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8def8aabee35accc7948d56b10bbd627
https://doi.org/10.1200/jco.21.00640
https://doi.org/10.1200/jco.21.00640
Autor:
Brittany L, Bychkovsky, Min-Tzu, Lo, Amal, Yussuf, Carrie, Horton, Marcy, Richardson, Holly, LaDuca, Judy E, Garber, Huma Q, Rana
Publikováno v:
Cancer. 128:1275-1283
Multiple primary cancers (MPCs) are a hallmark of cancer predisposition syndromes. Here the frequency of germline pathogenic variants (PVs) among patients with MPCs is reported.Patients with MPCs who underwent multigene panel testing from March 2012
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42d8ac8b519199545b0c5eb6f11cd62
https://doi.org/10.1002/cncr.34056
https://doi.org/10.1002/cncr.34056
Autor:
Tracy A. O'Mara, Tina Pesaran, Sharon E. Johnatty, Amanda B. Spurdle, Holly LaDuca, Paul A. James, Amal Yussuf, Jill S. Dolinsky
Publikováno v:
Human Mutation. 42:1265-1278
Hereditary endometrial cancer (EC) is most commonly attributed to pathogenic variants in mismatch repair (MMR) genes. Evidence supports existence of additional genetic risk factors in the context of multiple cancer diagnoses and/or family history of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e4ea4e6181ee7ddfdb3e8add0e211a
https://doi.org/10.1002/humu.24256
https://doi.org/10.1002/humu.24256
Autor:
Brittany L. Bychkovsky, Min-Tzu Lo, Amal Yussuf, Carrie Horton, Parichehr Hemyari, Holly LaDuca, Judy E. Garber, Rochelle Scheib, Huma Q. Rana
Publikováno v:
Breast Cancer Research and Treatment. 200:73-73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf3c1d9dfb49d23fae33c8cd0950d4f7
https://doi.org/10.1007/s10549-023-06928-w
https://doi.org/10.1007/s10549-023-06928-w
Autor:
Jill S. Dolinsky, Brigette Tippin Davis, David E. Goldgar, Tina Pesaran, Jenna Lilyquist, Jie Na, Holly LaDuca, Amal Yussuf, Nancy Niguidula, Elizabeth C. Chao, Chunling Hu, Hermela Shimelis, Steven N. Hart, Siddhartha Yadav, Fergus J. Couch, Kun Y. Lee, Stephanie Gutierrez, Eric C. Polley
Publikováno v:
JNCI Journal of the National Cancer Institute
To evaluate the racial and ethnic differences in prevalence of germline pathogenic variants (PVs) and the effect of race and ethnicity on breast cancer (BC) risk among carriers, results of multigene testing of 77 900 women with BC (non-Hispanic White
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f878a957b7b1952845553924295cf4
https://doi.org/10.1093/jnci/djaa167
https://doi.org/10.1093/jnci/djaa167
Autor:
Jill S. Dolinsky, Jessica L. Mester, Paul A. James, Tina Pesaran, Amal Yussuf, Cristina Fortuno, Amanda B. Spurdle, Kelly McGoldrick
Publikováno v:
Cancer Genetics. :11-17
Pathogenic germline variants in the TP53 gene predispose to a wide range of cancers, known collectively as Li-Fraumeni syndrome (LFS). There has been much research aimed to identify genotype-phenotype correlations, that is, differences between varian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ebd1e7d01d967f7f8893dd0a225376
https://doi.org/10.1016/j.cancergen.2020.09.002
https://doi.org/10.1016/j.cancergen.2020.09.002