Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Amaia Zabala Letona"'
Autor:
Rubén Gil-Redondo, Ricardo Conde, Chiara Bruzzone, Maria Luisa Seco, Maider Bizkarguenaga, Beatriz González-Valle, Angela de Diego, Ana Laín, Hansjörg Habisch, Christoph Haudum, Nicolas Verheyen, Barbara Obermayer-Pietsch, Sara Margarita, Serena Pelusi, Ignacio Verde, Nádia Oliveira, Adriana Sousa, Amaia Zabala-Letona, Aida Santos-Martin, Ana Loizaga-Iriarte, Miguel Unda-Urzaiz, Jasmin Kazenwadel, Georgy Berezhnoy, Tobias Geisler, Meinrad Gawaz, Claire Cannet, Hartmut Schäfer, Tammo Diercks, Christoph Trautwein, Arkaitz Carracedo, Tobias Madl, Luca Valenti, Manfred Spraul, Shelly C. Lu, Nieves Embade, José M. Mato, Oscar Millet
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Metabolic syndrome (MetS) is a cluster of medical conditions and risk factors correlating with insulin resistance that increase the risk of developing cardiometabolic health problems. The specific criteria for diagnosing MetS vary
Externí odkaz:
https://doaj.org/article/0f7d4a04add1447884a54f4d9ce65b6c
Autor:
Jana R. Crespo, Natalia Martín-Martín, Saioa Garcia-Longarte, Jon Corres-Mendizabal, Onintza Carlevaris, Ianire Astobiza, Amaia Zabala-Letona, Marc Guiu, Mikel Azkargorta, Monika Gonzalez-Lopez, Nuria Macías-Cámara, Phuong Doan, Félix Elortza, Isabel Mendizabal, Jukka Westermack, Roger R. Gomis, Amaia Ercilla, Arkaitz Carracedo
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-11 (2024)
Abstract Prostate cancer exhibits high prevalence and accounts for a high number of cancer-related deaths. The discovery and characterization of molecular determinants of aggressive prostate cancer represents an active area of research. The Immediate
Externí odkaz:
https://doaj.org/article/9d77cf5d40a74212b0e4aa7821487081
Autor:
Raquel García-Vílchez, Ana M. Añazco-Guenkova, Sabine Dietmann, Judith López, Virginia Morón-Calvente, Silvia D’Ambrosi, Paz Nombela, Kepa Zamacola, Isabel Mendizabal, Saioa García-Longarte, Amaia Zabala-Letona, Ianire Astobiza, Sonia Fernández, Alejandro Paniagua, Borja Miguel-López, Virginie Marchand, Diego Alonso-López, Angelika Merkel, Ignacio García-Tuñón, Aitziber Ugalde-Olano, Ana Loizaga-Iriarte, Isabel Lacasa-Viscasillas, Miguel Unda, Mikel Azkargorta, Félix Elortza, Laura Bárcena, Monika Gonzalez-Lopez, Ana M. Aransay, Tomás Di Domenico, Manuel A. Sánchez-Martín, Javier De Las Rivas, Sònia Guil, Yuri Motorin, Mark Helm, Pier Paolo Pandolfi, Arkaitz Carracedo, Sandra Blanco
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-36 (2023)
Abstract Newly growing evidence highlights the essential role that epitranscriptomic marks play in the development of many cancers; however, little is known about the role and implications of altered epitranscriptome deposition in prostate cancer. He
Externí odkaz:
https://doaj.org/article/23776f080b2242829817059af1fa8867
Autor:
Amaia Zabala-Letona, Amaia Arruabarrena-Aristorena, Sonia Fernandez-Ruiz, Cristina Viera, Onintza Carlevaris, Amaia Ercilla, Isabel Mendizabal, Teresa Martin, Alice Macchia, Laura Camacho, Mikel Pujana-Vaquerizo, Pilar Sanchez-Mosquera, Verónica Torrano, Natalia Martin-Martin, Patricia Zuniga-Garcia, Mireia Castillo-Martin, Aitziber Ugalde-Olano, Ana Loizaga-Iriarte, Miguel Unda, Jose M. Mato, Edurne Berra, Maria L. Martinez-Chantar, Arkaitz Carracedo
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-9 (2022)
Abstract Glycine N-Methyltransferase (GNMT) is a metabolic enzyme that integrates metabolism and epigenetic regulation. The product of GNMT, sarcosine, has been proposed as a prostate cancer biomarker. This enzyme is predominantly expressed in the li
Externí odkaz:
https://doaj.org/article/87b52f9737394abf853f3889be83cc38
Autor:
Rubén Rodríguez-Agudo, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, Pablo Fernández-Tussy, David Fernández-Ramos, Sofía Lachiondo-Ortega, Irene González-Recio, Clàudia Gil-Pitarch, María Mercado-Gómez, Laura Morán, Maider Bizkarguenaga, Fernando Lopitz-Otsoa, Petar Petrov, Miren Bravo, Sebastiaan Martijn Van Liempd, Juan Manuel Falcon-Perez, Amaia Zabala-Letona, Arkaitz Carracedo, Jose Vicente Castell, Ramiro Jover, Luis Alfonso Martínez-Cruz, Teresa Cardoso Delgado, Francisco Javier Cubero, María Isabel Lucena, Raúl Jesús Andrade, Jon Mabe, Jorge Simón, María Luz Martínez-Chantar
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 897 (2022)
Drug-induced liver injury (DILI) development is commonly associated with acetaminophen (APAP) overdose, where glutathione scavenging leads to mitochondrial dysfunction and hepatocyte death. DILI is a severe disorder without effective late-stage treat
Externí odkaz:
https://doaj.org/article/2ad42c57fdeb4f66bad2d0eabf53b813
Autor:
Begoña Porteiro, Marcos F. Fondevila, Teresa C. Delgado, Cristina Iglesias, Monica Imbernon, Paula Iruzubieta, Javier Crespo, Amaia Zabala-Letona, Johan Fernø, Bárbara González-Terán, Nuria Matesanz, Lourdes Hernández-Cosido, Miguel Marcos, Sulay Tovar, Anxo Vidal, Julia Sánchez-Ceinos, Maria M. Malagon, Celia Pombo, Juan Zalvide, Arkaitz Carracedo, Xabier Buque, Carlos Dieguez, Guadalupe Sabio, Miguel López, Patricia Aspichueta, María L. Martínez-Chantar, Ruben Nogueiras
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
p53 regulates lipid metabolism and fatty acid oxidation, and its inactivation promotes diet-induced liver steatosis. Here Porteiroet al. show that p53 deficiency leads to compensatory p63 upregulation, which, in turn, triggers endoplasmic reticulum s
Externí odkaz:
https://doaj.org/article/313d0cad52134cc688396b50bf36ea35
Autor:
Natalia Martín-Martín, Marco Piva, Jelena Urosevic, Paula Aldaz, James D. Sutherland, Sonia Fernández-Ruiz, Leire Arreal, Verónica Torrano, Ana R. Cortazar, Evarist Planet, Marc Guiu, Nina Radosevic-Robin, Stephane Garcia, Iratxe Macías, Fernando Salvador, Giacomo Domenici, Oscar M. Rueda, Amaia Zabala-Letona, Amaia Arruabarrena-Aristorena, Patricia Zúñiga-García, Alfredo Caro-Maldonado, Lorea Valcárcel-Jiménez, Pilar Sánchez-Mosquera, Marta Varela-Rey, Maria Luz Martínez-Chantar, Juan Anguita, Yasir H. Ibrahim, Maurizio Scaltriti, Charles H. Lawrie, Ana M. Aransay, Juan L. Iovanna, Jose Baselga, Carlos Caldas, Rosa Barrio, Violeta Serra, Maria dM Vivanco, Ander Matheu, Roger R. Gomis, Arkaitz Carracedo
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Targeting PML in acute promyelocytic leukaemia has changed the outcome of patients with this disease. Here, the authors demonstrated that PML is also a potential therapeutic target in breast cancer where it specifically regulates cancer initiating ce
Externí odkaz:
https://doaj.org/article/e6f5403164b5464bb99d566e04f080ef
Autor:
Erika Monelli, Pilar Villacampa, Amaia Zabala-Letona, Anabel Martinez-Romero, Judith Llena, Daniel Beiroa, Leonor Gouveia, Iñigo Chivite, Sebastián Zagmutt, Pau Gama-Perez, Oscar Osorio-Conles, Laia Muixi, Ainara Martinez-Gonzalez, Sandra D. Castillo, Natalia Martín-Martín, Pau Castel, Lorea Valcarcel-Jimenez, Irene Garcia-Gonzalez, Josep A. Villena, Sonia Fernandez-Ruiz, Dolors Serra, Laura Herrero, Rui Benedito, Pablo Garcia-Roves, Josep Vidal, Paul Cohen, Rubén Nogueiras, Marc Claret, Arkaitz Carracedo, Mariona Graupera
Publikováno v:
Nature Metabolism. 4:327-343
Reciprocal interactions between endothelial cells (ECs) and adipocytes are fundamental to maintain white adipose tissue (WAT) homeostasis, as illustrated by the activation of angiogenesis upon WAT expansion, a process that is impaired in obesity. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4a65755dc2993a750f18cb4aa2b0f4
https://doi.org/10.1038/s42255-022-00544-6
https://doi.org/10.1038/s42255-022-00544-6
Autor:
Arkaitz Carracedo, James D. Sutherland, Rosa Barrio, Antonio Gomez-Muñoz, Ana M. Aransay, Pilar Sánchez-Mosquera, Marco Piva, Amaia Arruabarrena-Aristorena, Lorea Valcárcel-Jiménez, Miguel Unda, Ana Loizaga-Iriarte, Aitziber Ugalde-Olano, Patricia Zúñiga-García, Ianire Astobiza, Verónica Torrano, Ana R. Cortazar, Mireia Castillo-Martin, Laura Camacho, Leire Arreal, Sonia Fernández-Ruiz, Amaia Zabala-Letona, Natalia Martín-Martín
The nuclear receptor PPAR-β/δ (PPARD) has essential roles in fatty acid catabolism and energy homeostasis as well as cell differentiation, inflammation, and metabolism. However, its contributions to tumorigenesis are uncertain and have been dispute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::651724c4f1b416ceccd0e6bb409ff0f4
https://doi.org/10.1158/0008-5472.c.6509801
https://doi.org/10.1158/0008-5472.c.6509801
Autor:
Arkaitz Carracedo, James D. Sutherland, Rosa Barrio, Antonio Gomez-Muñoz, Ana M. Aransay, Pilar Sánchez-Mosquera, Marco Piva, Amaia Arruabarrena-Aristorena, Lorea Valcárcel-Jiménez, Miguel Unda, Ana Loizaga-Iriarte, Aitziber Ugalde-Olano, Patricia Zúñiga-García, Ianire Astobiza, Verónica Torrano, Ana R. Cortazar, Mireia Castillo-Martin, Laura Camacho, Leire Arreal, Sonia Fernández-Ruiz, Amaia Zabala-Letona, Natalia Martín-Martín
Suppl Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f976bf0b2bc01cf063beb00531c5f74
https://doi.org/10.1158/0008-5472.22417259
https://doi.org/10.1158/0008-5472.22417259