Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Amaia M. Arranz"'
Autor:
Julia TCW, Amaia M. Arranz
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/d05aaf5822bf4eda80892b27c10edfa3
Autor:
Pranav Preman, Amaia M. Arranz
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113129- (2023)
Lee et al.1 report that loss of the Alzheimer’s disease risk factor SORL1 results in neuron-specific reduction in APOE and CLU, altered lipid homeostasis, and increased Aβ levels and phosphorylated Tau, both rescued by stabilizing retromer or enha
Externí odkaz:
https://doaj.org/article/a5358abc981a4e74b2ffa2c3b83efadf
Publikováno v:
Cells, Vol 10, Iss 3, p 540 (2021)
Astrocytes perform a wide variety of essential functions defining normal operation of the nervous system and are active contributors to the pathogenesis of neurodegenerative disorders such as Alzheimer’s among others. Recent data provide compelling
Externí odkaz:
https://doaj.org/article/4a678b9369e941229a6228c937aef0d1
Publikováno v:
Neurobiology of Disease, Vol 37, Iss 1, Pp 156-165 (2010)
Transient focal cerebral ischemia leads to extensive excitotoxic glial damage in the subcortical white matter. Efficient reuptake of released glutamate is essential for preventing glutamate receptor overstimulation and neuronal and glial death. The p
Externí odkaz:
https://doaj.org/article/a522bd0ee563490ab17c71f4b8307260
Publikováno v:
Annals of the New York Academy of Sciences. 1518:120-130
The evolution of the nervous system progressed through cellular diversification and specialization of functions. Conceptually, the nervous system is composed of electrically excitable neuronal networks connected by chemical synapses and nonexcitable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281864e4790f794e572df88a05da1b54
https://doi.org/10.1111/nyas.14917
https://doi.org/10.1111/nyas.14917
Autor:
Sriram Balusu, Katrien Horré, Nicola Thrupp, An Snellinx, Lutgarde Serneels, Iordana Chrysidou, Amaia M. Arranz, Annerieke Sierksma, Joel Simrén, Thomas K. Karikari, Henrik Zetterberg, Wei-Ting Chen, Dietmar Rudolf Thal, Evgenia Salta, Mark Fiers, Bart De Strooper
/SummaryNeuronal cell loss is a defining feature of Alzheimer’s disease (AD), but it remains unclear how neurons die and how this relates to other defining characteristics of the disease1. Existing in vivo AD models only partially recapitulate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c499276efe0298a4d349e5c0af55677a
https://doi.org/10.1101/2022.02.18.480849
https://doi.org/10.1101/2022.02.18.480849
Autor:
Julia Tcw, Amaia M. Arranz, Dietmar Rudolf Thal, Bart De Strooper, Pranav Preman, Nikky Corthout, Sara Calafate, An Snellinx, Alison Goate, Maria Alfonso-Triguero, Sebastian Munck
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-18 (2021)
Molecular Neurodegeneration
Molecular Neurodegeneration
BackgroundIncreasing evidence for a direct contribution of astrocytes to neuroinflammatory and neurodegenerative processes causing Alzheimer’s disease comes from molecular and functional studies in rodent models. However, these models may not fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8694db7852ed2998191590779db6331f
https://doi.org/10.1186/s13024-021-00487-8
https://doi.org/10.1186/s13024-021-00487-8
Autor:
Bart De Strooper, Amaia M. Arranz
Publikováno v:
The Lancet Neurology. 18:406-414
BACKGROUND: Astrocytes, also called astroglia, maintain homoeostasis of the brain by providing trophic and metabolic support to neurons. They recycle neurotransmitters, stimulate synaptogenesis and synaptic neurotransmission, form part of the blood-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2598d2b74f2090866e5a25ef8608d24
https://doi.org/10.1016/s1474-4422(18)30490-3
https://doi.org/10.1016/s1474-4422(18)30490-3
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
Cells
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Cells, Vol 10, Iss 540, p 540 (2021)
Universidad de Cantabria (UC)
instname
Cells
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Cells, Vol 10, Iss 540, p 540 (2021)
Universidad de Cantabria (UC)
Astrocytes perform a wide variety of essential functions defining normal operation of the nervous system and are active contributors to the pathogenesis of neurodegenerative disorders such as Alzheimer’s among others. Recent data provide compelling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd0e4eda46e70a2914ab873799d112c
http://hdl.handle.net/10810/50827
http://hdl.handle.net/10810/50827