Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Amaia Azqueta"'
Autor:
Andrew R. Collins, Amaia Azqueta, Trine Gjesti Bentzen, Torgrim M. Langleite, Yolanda Lorenzo, Sergey Shaposhnikov
Publikováno v:
Bioingeniøren, Vol 45, Iss 5, Pp 6-11 (2010)
DNA damage is recognised as the first step in the process of carcinogenesis, induced by endogenous or environmental agents. At low levels, it is best detected with the comet assay (single cell gel electrophoresis), a method based on electrophoresis o
Externí odkaz:
https://doaj.org/article/48cd8c40e59d4ecc896447719db41e3e
Autor:
Noemi Sola-Sevilla, Alberto Mesa-Lombardo, Mikel Aleixo, Sara Exposito, Teresa Diaz-Perdigón, Amaia Azqueta, Farzad Zamani, Takayoshi Suzuki, Silvia Maioli, Francesca Eroli, Anna Matton, Maite Solas, Rosa M. Tordera, Eduardo D. Martín, Elena Puerta
Sirtuin 2 (SIRT2) has been proposed to have a central role on aging, inflammation, cancer and neurodegenerative diseases; however, its specific function remains controversial. Recent studies propose SIRT2 pharmacological inhibition as a therapeutic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82219c93bb52e71bc02dd5b9aa017350
https://doi.org/10.21203/rs.3.rs-2175455/v1
https://doi.org/10.21203/rs.3.rs-2175455/v1
Autor:
Amaia Azqueta, Tânia Almeida, Ariane Vettorazzi, Eduardo Rocha, Joana Ferreira, Alice A. Ramos
Publikováno v:
Environmental toxicology and pharmacology. 59
In the present study, we evaluate the in vitro cytotoxicity of fucoxanthin (Fx) on two human leukemia cell lines, K562 and TK6, alone and in combination with the conventional anticancer drugs imatinib (Imat) and doxorubicin (Dox). For the purpose, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee8c4f6cea53740d0c85f4dbf0bfb7b
https://pubmed.ncbi.nlm.nih.gov/29518678
https://pubmed.ncbi.nlm.nih.gov/29518678
Publikováno v:
International journal of pharmaceutics. 530(1-2)
Gantrez ® AN 119-based NPs have been developed as oral drug carriers due to their strong bioadhesive interaction with components of the gastrointestinal mucosa and to their adaptable surface. The use of mannosamine to coat Gantrez ® AN 119-based NP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedf786ed51ade96a61bd6f263cd5216
https://pubmed.ncbi.nlm.nih.gov/28750895
https://pubmed.ncbi.nlm.nih.gov/28750895
Autor:
Adela López de Cerain, Leire Arbillaga, Amaia Azqueta, Gisela Pachón, Edmond E. Creppy, Marta Cascante
Publikováno v:
Chemico-Biological Interactions. 168:95-105
Some anticancer compounds are pro-drugs which give rise to toxic species through enzymatic reduction. The quinoxaline-di-N-oxide derivative Q-85 HCl (7-chloro-3-[[(N,N-dimethylamino)propyl]amino]-2-quinoxalinecarbonitrile 1,4-di-N-oxide hydrochloride
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d816e774f76109c7605a37306245d61
https://doi.org/10.1016/j.cbi.2007.02.013
https://doi.org/10.1016/j.cbi.2007.02.013
Autor:
Eduardo E. Castellano, Adela López de Cerain, Gabriel Sagrera, Mauricio Cabrera, Antonio Monge, Amaia Azqueta, Anabel Vidal, Mercedes González, Gustavo Seoane, Oscar E. Piro, Hugo Cerecetto, Gabriela Falchi, M. Laura Lavaggi, Macarena Simoens
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:3356-3367
A series of synthetic chalcones, flavanones, and flavones has been synthesized and evaluated for antitumor activity against the human kidney carcinoma cells TK-10, human mammary adenocarcinoma cells MCF-7 (estrogen receptor-positive), and human colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b39728f574ff52541da3a45a27ed127
https://doi.org/10.1016/j.bmc.2007.03.031
https://doi.org/10.1016/j.bmc.2007.03.031
Publikováno v:
Toxicology. 232:294-302
Zearalenone (ZEN) is a fusarial mycotoxin with several adverse effects in laboratory and domestic animals including mainly estrogenicity. While most ZEN toxic effects have been quite well investigated, little is known regarding its mechanism of toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d525132786e9b7a8f188f6e4431b75a9
https://doi.org/10.1016/j.tox.2007.01.015
https://doi.org/10.1016/j.tox.2007.01.015
Publikováno v:
Toxicology and Applied Pharmacology, 220(2), 216-224. Elsevier Science
Ochratoxin A (OTA) is a mycotoxin often found in cereals and agricultural products. There is unequivocal evidence of renal carcinogenicity of OTA in male rats, although the mechanism of action is unknown. At present, available data support an epigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6962d227fcec0637ef0e229d20e12213
https://doi.org/10.1016/j.taap.2007.01.008
https://doi.org/10.1016/j.taap.2007.01.008
Publikováno v:
Mutagenesis. 22:35-42
Ochratoxin A (OTA) is a mycotoxin produced by species of the genera Aspergillus and Penicillium. The kidneys are the target organ of this mycotoxin and it is considered a potent renal carcinogen in male rats. The mechanisms of its genotoxicity and ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2432976a55df6a25593f8dcb2a9d87c
https://doi.org/10.1093/mutage/gel049
https://doi.org/10.1093/mutage/gel049
Autor:
Antonio Monge, Mercedes González, María H. Torre, Pabla Noblía, Dinorah Gambino, Amaia Azqueta, Antonio J. Costa-Filho, Adela López de Cerain, Beatriz S. Parajón-Costa, María Laura Lavaggi, Marisol Vieites, Hugo Cerecetto
Publikováno v:
Journal of Inorganic Biochemistry. 100:1358-1367
A new vanadyl complex with the formula VO(L1)2, where L1=3-amino-6(7)-chloroquinoxaline-2-carbonitrile N(1), N(4)-dioxide, has been synthesized and characterized by elemental analyses, conductometry, fast atom bombardment mass spectroscopy (FAB-MS) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e02e9ba92afc2feeeffe04b3853054
https://doi.org/10.1016/j.jinorgbio.2006.03.012
https://doi.org/10.1016/j.jinorgbio.2006.03.012