Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Amaia, Lujambio"'
Autor:
Marta Piqué-Gili, Carmen Andreu-Oller, Agavni Mesropian, Roger Esteban-Fabró, Marina Bárcena-Varela, Marina Ruiz de Galarreta, Carla Montironi, Iris Martinez-Quetglas, Sarah Cappuyns, Judit Peix, Ieva Keraite, Albert Gris-Oliver, Elisa Fernández-Martínez, Ezequiel Mauro, Miguel Torres-Martin, Jordi Abril-Fornaguera, Katherine E. Lindblad, Diether Lambrechts, Jeroen Dekervel, Swan N. Thung, Daniela Sia, Amaia Lujambio, Roser Pinyol, Josep M. Llovet
Publikováno v:
JHEP Reports, Vol 6, Iss 11, Pp 101212- (2024)
Background & Aims: Transforming growth factor β (TGF-β) plays an oncogenic role in advanced cancer by promoting cell proliferation, metastasis and immunosuppression. PMEPA1 (prostate transmembrane protein androgen induced 1) has been shown to promo
Externí odkaz:
https://doaj.org/article/93d51b39e7c4419c83008f56aa023b9c
Autor:
Sofia Lachiondo-Ortega, Claudia M. Rejano-Gordillo, Jorge Simon, Fernando Lopitz-Otsoa, Teresa C. Delgado, Krystyna Mazan-Mamczarz, Naroa Goikoetxea-Usandizaga, L. Estefanía Zapata-Pavas, Ana García-del Río, Pietro Guerra, Patricia Peña-Sanfélix, Natalia Hermán-Sánchez, Ruba Al-Abdulla, Carmen Fernandez-Rodríguez, Mikel Azkargorta, Alejandro Velázquez-Cruz, Joris Guyon, César Martín, Juan Diego Zalamea, Leire Egia-Mendikute, Arantza Sanz-Parra, Marina Serrano-Maciá, Irene González-Recio, Monika Gonzalez-Lopez, Luis Alfonso Martínez-Cruz, Patrizia Pontisso, Ana M. Aransay, Rosa Barrio, James D. Sutherland, Nicola G.A. Abrescia, Félix Elortza, Amaia Lujambio, Jesus M. Banales, Raúl M. Luque, Manuel D. Gahete, Asís Palazón, Matias A. Avila, Jose J. G. Marin, Supriyo De, Thomas Daubon, Antonio Díaz-Quintana, Irene Díaz-Moreno, Myriam Gorospe, Manuel S. Rodríguez, María Luz Martínez-Chantar
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113924- (2024)
Summary: The posttranslational modification of proteins critically influences many biological processes and is a key mechanism that regulates the function of the RNA-binding protein Hu antigen R (HuR), a hub in liver cancer. Here, we show that HuR is
Externí odkaz:
https://doaj.org/article/ac05448b67bf43d08eefd6737eb5e995
Autor:
Zhihong Chen, Nishant Soni, Gonzalo Pinero, Bruno Giotti, Devon J. Eddins, Katherine E. Lindblad, James L. Ross, Montserrat Puigdelloses Vallcorba, Tanvi Joshi, Angelo Angione, Wes Thomason, Aislinn Keane, Nadejda M. Tsankova, David H. Gutmann, Sergio A. Lira, Amaia Lujambio, Eliver E. B. Ghosn, Alexander M. Tsankov, Dolores Hambardzumyan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Myeloid cells are the predominant cell type in the tumor microenvironment of human and murine glioblastoma (GBM). By generating a mouse model deficient for all monocyte chemoattractant proteins, here the authors show that blocking monocyte recruitmen
Externí odkaz:
https://doaj.org/article/358a75b5c19346a48cc38b1a4dc8779e
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Hepatocellular carcinoma (HCC) is the fourth cause of cancer-related mortality worldwide. While many targeted therapies have been developed, the majority of HCC tumors do not harbor clinically actionable mutations. Protein-level aberrations, especial
Externí odkaz:
https://doaj.org/article/53e511083f754d48830e5c5906a6e436
Autor:
Amaia Lujambio, Romain Donne, Brian Brown, Marina Barcena-Varela, Alice Kamphorst, Katherine Lindblad, Marina Ruiz de Galarreta, Ian Liebling, David Repáraz, Melissa Yao, Maxime Dhainaut
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/811463826bd94493b402833b6e04b3dc
Autor:
Amaia Lujambio, Thomas Yau, Lipika Goyal, Andrew X Zhu, Ignacio Melero, Tim F Greten, Ann-Lii Cheng, Bruno Sangro, David J Pinato, Peter R Galle, Ghassan K Abou-Alfa, Austin G Duffy, Anthony B. El-Khoueiry, Richard S Finn, Aiwu Ruth He, Ahmed O Kaseb, Robin Kate Kelley, Riccardo Lencioni, Donna Mabry Hrones, Roberto I Troisi, Andrea Wilson Woods
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Patients with advanced hepatocellular carcinoma (HCC) have historically had few options and faced extremely poor prognoses if their disease progressed after standard-of-care tyrosine kinase inhibitors (TKIs). Recently, the standard of care for HCC ha
Externí odkaz:
https://doaj.org/article/c395a80c692945e793e9d243958829ae
Autor:
Polona Safaric Tepes, Debjani Pal, Trine Lindsted, Ingrid Ibarra, Amaia Lujambio, Vilma Jimenez Sabinina, Serif Senturk, Madison Miller, Navya Korimerla, Jiahao Huang, Lawrence Glassman, Paul Lee, David Zeltsman, Kevin Hyman, Michael Esposito, Gregory J Hannon, Raffaella Sordella
Publikováno v:
eLife, Vol 10 (2021)
Despite current advancements in research and therapeutics, lung cancer remains the leading cause of cancer-related mortality worldwide. This is mainly due to the resistance that patients develop against chemotherapeutic agents over the course of trea
Externí odkaz:
https://doaj.org/article/8f753d647a7d4f28ad16d9538172ef03
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100440- (2021)
Summary: Studies to identify genes relevant to mammalian hepatocyte biology in vivo are largely carried out using germline genetic-engineering approaches, which can be costly and time-consuming. We describe hydrodynamic tail vein injection as an alte
Externí odkaz:
https://doaj.org/article/7914a39995594cca840f1e37ca8e8686
Autor:
Amanda J Craig, Teresa Garcia-Lezana, Marina Ruiz de Galarreta, Carlos Villacorta-Martin, Edgar G Kozlova, Sebastiao N Martins-Filho, Johann von Felden, Mehmet Eren Ahsen, Erin Bresnahan, Gabriela Hernandez-Meza, Ismail Labgaa, Delia D'Avola, Myron Schwartz, Josep M Llovet, Daniela Sia, Swan Thung, Bojan Losic, Amaia Lujambio, Augusto Villanueva
Publikováno v:
PLoS Genetics, Vol 17, Iss 6, p e1009589 (2021)
Cancer testis antigens (CTAs) are an extensive gene family with a unique expression pattern restricted to germ cells, but aberrantly reactivated in cancer tissues. Studies indicate that the expression (or re-expression) of CTAs within the MAGE-A fami
Externí odkaz:
https://doaj.org/article/cc9f4cfb85bd4a1686eaa53fc84df178
Autor:
Tao Qing, Tomi Jun, Katherine E. Lindblad, Amaia Lujambio, Michal Marczyk, Lajos Pusztai, Kuan-lin Huang
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 5, Pp 100276- (2021)
Summary: Tumors with DNA damage repair (DDR) deficiency accumulate genomic alterations that may serve as neoantigens and increase sensitivity to immune checkpoint inhibitor. However, over half of DDR-deficient tumors are refractory to immunotherapy,
Externí odkaz:
https://doaj.org/article/e72d6da104c0451b8da2c9c34623ad7a