Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase

Autor: Pierra Rouvière, Claire, Amador, Agnès, Badaroux, Eric, Convard, Thierry, Da Costa, Daniel, Dukhan, David, Griffe, Ludovic, Griffon, Jean-François, LaColla, Massimiliano, Leroy, Frédéric, Liuzzi, Michel, Loi, Anna Giulia, McCarville, Joe, Mascia, Valeria, Milhau, Julien, Onidi, Loredana, Paparin, Jean-Laurent, Rahali, Rachid, Sais, Efisio, Seifer, Maria, Surleraux, Dominique, Standring, David, Dousson, Cyril

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 15 September 2016 26(18):4536-4541

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Synthesis and pharmacokinetics of Valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine

Autor: Pierra, Claire, Amador, Agnès, Benzaria, Samira, Cretton-Scott, Erika, D'Amours, Marc, Mao, John, Mathieu, Steven, Moussa, Adel, Bridges, Edward G., Standring, David N., Sommadossi, Jean-Pierre, Storer, Richard, Gosselin, Gilles

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2006, 49, pp.6614-6620

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::26d67f5d56989876ce4f86d50b15031c
https://hal.archives-ouvertes.fr/hal-00111823

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Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.

Autor: Pierra C; Laboratoire Coopératif Idenix-CNRS-Université Montpellier II, Case Courrier 008, Université Montpellier II, Place Eugène Bataillon, 34095 Montpellier Cedex 5, France., Amador A, Benzaria S, Cretton-Scott E, D'Amours M, Mao J, Mathieu S, Moussa A, Bridges EG, Standring DN, Sommadossi JP, Storer R, Gosselin G

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2006 Nov 02; Vol. 49 (22), pp. 6614-20.