Scalable Process for High-Yield Production of PfCyRPA Using Insect Cells for Inclusion in a Malaria Virosome-Based Vaccine Candidate

Autor: Fernandes, B., Sousa, M., Castro, R., Schäfer, A., Hauser, J., Schulze, K., Amacker, M., Tamborrini, M., Pluschke, G., Alves, P. M., Fleury, S., Roldão, A.

Publikováno v: Fernandes, Bárbara; Sousa, Marcos; Castro, Rute; Schäfer, Anja; Hauser, Julia; Schulze, Kai; Amacker, Mario; Tamborrini, Marco; Pluschke, Gerd; Alves, Paula M; Fleury, Sylvain; Roldão, António (2022). Scalable Process for High-Yield Production of PfCyRPA Using Insect Cells for Inclusion in a Malaria Virosome-Based Vaccine Candidate. Frontiers in Bioengineering and Biotechnology, 10, p. 879078. Frontiers Media 10.3389/fbioe.2022.879078

Plasmodium falciparum cysteine-rich protective antigen (PfCyRPA) has been identified as a promising blood-stage candidate antigen to include in a broadly cross-reactive malaria vaccine. In the last couple of decades, substantial effort has been commi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0318a3212c3bb5918fb97057838c8ae7
https://boris.unibe.ch/170507/1/fbioe-10-879078.pdf

A low dose of RBD and TLR7/8 agonist displayed on influenza virosome particles protects rhesus macaque against SARS-CoV-2 challenge.

Autor: Koopman G; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands. koopman@bprc.nl., Amacker M; Mymetics SA, 4 Route de La Corniche, 1066, Epalinges, Switzerland.; Department for BioMedical Research DBMR, Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, 3008, Bern, Switzerland., Stegmann T; Mymetics BV, JH Oortweg 21, 2333 CH, Leiden, The Netherlands., Verschoor EJ; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Verstrepen BE; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Bhoelan F; Mymetics BV, JH Oortweg 21, 2333 CH, Leiden, The Netherlands., Bemelman D; Mymetics BV, JH Oortweg 21, 2333 CH, Leiden, The Netherlands., Böszörményi KP; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Fagrouch Z; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Kiemenyi-Kayere G; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Mortier D; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Verel DE; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Niphuis H; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Acar RF; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Kondova I; Animal Science Department, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Kap YS; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Bogers WMJM; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Mooij P; Department of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands., Fleury S; Mymetics SA, 4 Route de La Corniche, 1066, Epalinges, Switzerland. sylvain.fleury@mymetics.com.

Publikováno v: Scientific reports [Sci Rep] 2023 Mar 28; Vol. 13 (1), pp. 5074. Date of Electronic Publication: 2023 Mar 28.

P19-02. High protection of female macaques from repeated intravaginal challenges with SHIV-162P3 upon mucosal vaccination with Gp41 subunits-virosomes

Autor: Devillers G, Lopalco L, Mouz N, Amacker M, Roger M, Drillet A, Bomsel M, Zurbriggen R, Fleury S

Publikováno v: Retrovirology, Vol 6, Iss Suppl 3, p P322 (2009)

Externí odkaz: https://doaj.org/article/84658158c74c4ef5a29fdf8b16365337

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A novel inactivated virus system (InViS) for a fast and inexpensive assessment of viral disintegration.

Autor: Furer LA; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Particles-Biology Interactions, 9014, St. Gallen, Switzerland., Clement P; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Particles-Biology Interactions, 9014, St. Gallen, Switzerland., Herwig G; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Biomimetic Membranes and Textiles, 9014, St. Gallen, Switzerland., Rossi RM; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Biomimetic Membranes and Textiles, 9014, St. Gallen, Switzerland., Bhoelan F; Mymetics BV, 2333 CH, Leiden, The Netherlands., Amacker M; Mymetics SA, 1066, Epalinges, Switzerland., Stegmann T; Mymetics BV, 2333 CH, Leiden, The Netherlands.; Department of Pulmonary Medicine, Bern University Hospital, University of Bern, 3012, Bern, Switzerland., Buerki-Thurnherr T; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Particles-Biology Interactions, 9014, St. Gallen, Switzerland., Wick P; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Particles-Biology Interactions, 9014, St. Gallen, Switzerland. peter.wick@empa.ch.

Publikováno v: Scientific reports [Sci Rep] 2022 Jul 08; Vol. 12 (1), pp. 11583. Date of Electronic Publication: 2022 Jul 08.