Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Américo J S, Alves"'
Autor:
Américo J. S. Alves, Nuno G. Alves, Inês Bártolo, Diana Fontinha, Soraia Caetano, Miguel Prudêncio, Nuno Taveira, Teresa M. V. D. Pinho e Melo
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The molecular architecture of spirocyclic compounds has been widely explored within the medicinal chemistry field to obtain new compounds with singular three-dimensional pharmacophoric features and improved bioactivity. Herein, the synthesis of 68 ne
Externí odkaz:
https://doaj.org/article/5cc9ca220a9346a994a73430480ac15c
Publikováno v:
RSC advances. 12(48)
The first examples of the diastereoselective 1,3-dipolar cycloaddition reaction of nitrile oxides and 6-alkylidene penicillanates leading to chiral spiroisoxazoline-penicillanates are reported. The synthesis of this new type of penicillanate involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81f8ad364ce2562ae4f4d8f3a856165a
https://pubmed.ncbi.nlm.nih.gov/36349033
https://pubmed.ncbi.nlm.nih.gov/36349033
Publikováno v:
Advanced Synthesis & Catalysis. 363:2464-2501
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d921f8f54a2882ee3f11e548d62bdc8
https://doi.org/10.1002/adsc.202100013
https://doi.org/10.1002/adsc.202100013
Publikováno v:
Organic Chemistry Frontiers. 8:3543-3593
Spiro-γ-lactams (spiropyrrolidin-2-ones) are a class of spirocyclic compounds that are present in a wide range of synthetic bioactive and naturally occurring molecules. The increasing attention to spirocyclic lactams in drug discovery has been accom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75951847d2bef223944ed2176dc64327
https://doi.org/10.1039/d0qo01564d
https://doi.org/10.1039/d0qo01564d
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e98dabf62db1e22bdc768d210d5d55
https://doi.org/10.1002/ejoc.202001085
https://doi.org/10.1002/ejoc.202001085
Autor:
Denise Francisco, Inês Bártolo, Maria I. L. Soares, Nuno G. Alves, Susana Lopes, Teresa M. V. D. Pinho e Melo, Américo J. S. Alves, Nuno Taveira, Diana Fontinha, Miguel Prudêncio, Carlos J. V. Simões
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© 2021 Elsevier Masson SAS. All rights reserved.
The synthesis and antimicrobial activity of new spiro-β-lactams is reported. The design of the new molecules was based on the structural modulation of two previously identified lead spiro-penici
The synthesis and antimicrobial activity of new spiro-β-lactams is reported. The design of the new molecules was based on the structural modulation of two previously identified lead spiro-penici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e9998b1b0974b5f04598640674932e
Autor:
Susana Lopes, Manuel R. Teixeira, José Mesquita-Bastos, Daniela Figueiredo, Américo J. S. Alves, Fernando Ribeiro, José Carlos Oliveira, Jorge Polónia
Publikováno v:
European Heart Journal. 42
Introduction Resistant hypertension is a major challenge of modern cardiovascular medicine, as it is a puzzling problem without a clear solution. Exercise training clearly reduces blood pressure (BP) and oxidative stress in patients with hypertension
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec5071ffe244090bad5cc7abdf31f79f
https://doi.org/10.1093/eurheartj/ehab724.2392
https://doi.org/10.1093/eurheartj/ehab724.2392
Autor:
Inês Bártolo, Inês Moranguinho, Paloma Gonçalves, Ana Rita Diniz, Pedro Borrego, Francisco Martin, Inês Figueiredo, Perpétua Gomes, Fátima Gonçalves, Américo J. S. Alves, Nuno Alves, Umbelina Caixas, Inês V. Pinto, Isabel Barahona, Teresa M. V. D. Pinho e Melo, Nuno Taveira
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 14300
Funding Information: This work was supported by Fundação para a Ciência e Tecnologia (FCT), Portugal, Aga Khan Development Network (AKDN)–Portugal Collaborative Research Network in Portuguese-speaking countries in Africa (project 332821690). CQC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4ed9bd16d45e0c34c4358ce86dc467
https://doi.org/10.3390/ijms232214300
https://doi.org/10.3390/ijms232214300
Autor:
Susana Lopes, José Mesquita-Bastos, Daniela Figueiredo, Catarina Garcia, Jorge Polónia, Américo J. S. Alves, Fernando Ribeiro, José Carlos Oliveira, Pedro Carvalho
Publikováno v:
European Journal of Cardiovascular Nursing. 20
Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main funding source(s): FEDER Funds through the Operational Competitiveness Factors Program—COMPETE National Funds through the Portuguese Foundation for Science and T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47a2ce36fb4d682a2dd774d5486163be
https://doi.org/10.1093/eurjcn/zvab060.033
https://doi.org/10.1093/eurjcn/zvab060.033
Autor:
Cátia Leitão, Guilherme Veiga Guimarães, Fernando Ribeiro, José Carlos Oliveira, José Mesquita-Bastos, João L. Viana, Verónica Ribau, Daniela Figueiredo, Susana Bertoquini, Pedro Carvalho, Catarina Garcia, Jorge Polónia, Susana Lopes, Américo J. S. Alves
Publikováno v:
European Journal of Cardiovascular Nursing. 20
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Portuguese Foundation for Science and Technology (FCT) European Regional Development Fund – Operational Competitiveness Factors Program (COMPETE) Background Physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::233c14f5922241fed9dc2fb439e69d2e
https://doi.org/10.1093/eurjcn/zvab060.034
https://doi.org/10.1093/eurjcn/zvab060.034