Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amélie Tourette"'
Autor:
Patrick Bogdanowicz, Paul Bensadoun, Maïté Noizet, Benoît Béganton, Armony Philippe, Sandrine Alvarez-Georges, Gautier Doat, Amélie Tourette, Sandrine Bessou-Touya, Jean-Marc Lemaitre, Hélène Duplan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Intrinsic and extrinsic factors, including lifestyle and sun exposure, can contribute to cell senescence, which impairs skin homeostasis, that may in turn lead to skin aging. Senescent cells have a specific secretome, called the senescence-a
Externí odkaz:
https://doaj.org/article/ba427c63495245dba57d832ddb81cc9d
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 388:509-516
N-methyl-d-aspartate (NMDA) receptor channels are implicated in a wide range of physiological and pathophysiological processes, and a large number of pharmacological agents have been introduced that target the receptor via diverse mechanisms of actio
Publikováno v:
European Journal of Pharmacology. 669:51-58
N-desmethylclozapine (NDMC or norclozapine) is the major active metabolite of the antipsychotic clozapine in humans. The activity of NDMC differs from clozapine at a number of neurotransmitter receptors, probably influencing the pharmacological effec
Autor:
Stéphanie Tardif, Amélie Tourette, David Troulier, Antoine Dumoulin, Marie‐Thérèse Calmettes, Delphine Denais-Lalieve, Marie-Christine Ailhaud, Claudie Cathala, Luc De Vries, Isabelle Rauly-Lestienne, Anne-Dominique Degryse, Emilie Lauressergues, Didier Cussac, Fabrice Lestienne, Peter Heusler
Publikováno v:
Pharmacology Research & Perspectives
The Hedgehog (HH) pathway has been linked to the formation of basal cell carcinoma (BCC), medulloblastoma, and other cancers. The recently approved orally active drugs vismodegib (GDC‐0449) and sonidegib (LDE–225) were not only efficacious for th
Publikováno v:
European journal of pharmacology. 669(1-3)
N-desmethylclozapine (NDMC or norclozapine) is the major active metabolite of the antipsychotic clozapine in humans. The activity of NDMC differs from clozapine at a number of neurotransmitter receptors, probably influencing the pharmacological effec
Autor:
Philippe Funes, Bernard Vacher, Peter Heusler, Marc Marien, Amélie Tourette, Philippe Chopin, Didier Cussac
Publikováno v:
Journal of medicinal chemistry. 53(19)
We report the discovery of a new family of α(2) adrenergic receptor antagonists derived from atipamezole. Affinities of the compounds at human α(2) and α(1b) receptors as well as their functional activities at hα(2A) receptors were determined in
Autor:
Peter Heusler, Guillaume Croville, Amélie Tourette, Isabelle Rauly-Lestienne, Marie-Christine Ailhaud, Didier Cussac, Stéphanie Tardif
Publikováno v:
European Journal of Pharmacology
European Journal of Pharmacology, Elsevier, 2010, 640 (1-3), pp.8-14. ⟨10.1016/j.ejphar.2010.04.034⟩
European Journal of Pharmacology, Elsevier, 2010, 640 (1-3), pp.8-14. ⟨10.1016/j.ejphar.2010.04.034⟩
8-OH-DPAT [8-hydroxy-2-(di-n-propylamino)tetralin] is the prototypical agonist at serotonin 5-HT1A receptors; however, activity at other targets contributes to the functional effects of the compound as well. We examined the properties of 8-OH-DPAT an
Autor:
Peter Heusler, Christiane Palmier, Stéphanie Tardif, Didier Cussac, Liesbeth A. Bruins Slot, Marie-Christine Ailhaud, Isabelle Rauly-Lestienne, Amélie Tourette
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 379(1)
Agonist activity at recombinant human dopamine D4.4 receptors was compared in stably transfected CHO cells using two functional readouts: G protein activation by [35S]GTPgammaS binding and phosphorylation of extracellular signal-regulated kinase 1/2