Výsledky vyhledávání - "Amélie Slembrouck‐Brec"

Akademický článek

Generation of human induced pluripotent stem cell lines from a subject with UBAP1L-associated retinal dystrophy and CRISPR/cas9-corrected isogenic iPSC lines

Autor: Andréa Amprou, Tasnim Ben Yacoub, Camille Letellier, Vincenzo Degaetano, Cécile Méjécase, Leila Azizzadeh Pormehr, Christel Condroyer, Amélie Slembrouck-Brec, Juliette Wohlschlegel, Olivier Goureau, Christina Zeitz, Isabelle Audo

Publikováno v: Stem Cell Research, Vol 81, Iss , Pp 103558- (2024)

A Human induced pluripotent stem cell (iPSC) line was generated from dermal fibroblasts of a patient affected with an autosomal recessive retinal dystrophy carrying the homozygous c.910-7G>A variant in UBAP1L. Three isogenic control iPSC lines derive

Externí odkaz: https://doaj.org/article/cfe1bf2bef494c38813b8b13c8c4cb1d

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Akademický článek

Dynamic full-field optical coherence tomography module adapted to commercial microscopes allows longitudinal in vitro cell culture study

Autor: Tual Monfort, Salvatore Azzollini, Jérémy Brogard, Marilou Clémençon, Amélie Slembrouck-Brec, Valerie Forster, Serge Picaud, Olivier Goureau, Sacha Reichman, Olivier Thouvenin, Kate Grieve

Publikováno v: Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)

Abstract Dynamic full-field optical coherence tomography (D-FFOCT) has recently emerged as a label-free imaging tool, capable of resolving cell types and organelles within 3D live samples, whilst monitoring their activity at tens of milliseconds reso

Externí odkaz: https://doaj.org/article/d7c6030c66464d5a921793a68612340c

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Akademický článek

Generation of gene corrected human isogenic iPSC lines (IDVi003-A_CR13, IDVi003-A_CR21, IDVi003-A_CR24) from an inherited retinal dystrophy patient-derived IPSC line ITM2B-5286-3 (IDVi003-A) carrying the ITM2B c.782A > C variant using CRISPR/Cas9

Autor: Tasnim Ben yacoub, Camille Letellier, Juliette Wohlschlegel, Christel Condroyer, Amélie Slembrouck-Brec, Olivier Goureau, Christina Zeitz, Isabelle Audo

Publikováno v: Stem Cell Research, Vol 71, Iss , Pp 103166- (2023)

The ITM2B-related retinal dystrophy (ITM2B-RD) was identified within patients carrying the autosomal dominant variant [c.782A > C, p.(Glu261Ala)] in ITM2B from whom induced pluripotent stem cell (IPSC) lines were previously generated. Here, we report

Externí odkaz: https://doaj.org/article/bc69cd3fd8fe48078ae624987b44ed21

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Akademický článek

Modeling PRPF31 retinitis pigmentosa using retinal pigment epithelium and organoids combined with gene augmentation rescue

Autor: Amélie Rodrigues, Amélie Slembrouck-Brec, Céline Nanteau, Angélique Terray, Yelyzaveta Tymoshenko, Yvrick Zagar, Sacha Reichman, Zhouhuan Xi, José-Alain Sahel, Stéphane Fouquet, Gael Orieux, Emeline F. Nandrot, Leah C. Byrne, Isabelle Audo, Jérôme E. Roger, Olivier Goureau

Publikováno v: npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-22 (2022)

Abstract Mutations in the ubiquitously expressed pre-mRNA processing factor (PRPF) 31 gene, one of the most common causes of dominant form of Retinitis Pigmentosa (RP), lead to a retina-specific phenotype. It is uncertain which retinal cell types are

Externí odkaz: https://doaj.org/article/9c275654ee034394a4e7eff764d4f7bb

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Akademický článek

Generation of a Transplantable Population of Human iPSC-Derived Retinal Ganglion Cells

Autor: Oriane Rabesandratana, Antoine Chaffiol, Antoine Mialot, Amélie Slembrouck-Brec, Corentin Joffrois, Céline Nanteau, Amélie Rodrigues, Giuliana Gagliardi, Sacha Reichman, José-Alain Sahel, Alain Chédotal, Jens Duebel, Olivier Goureau, Gael Orieux

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

Optic neuropathies are a major cause of visual impairment due to retinal ganglion cell (RGC) degeneration. Human induced-pluripotent stem cells (iPSCs) represent a powerful tool for studying both human RGC development and RGC-related pathological mec

Externí odkaz: https://doaj.org/article/1110a7efc5424ef18f2b689f99244a88

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Akademický článek

Characterization and Transplantation of CD73-Positive Photoreceptors Isolated from Human iPSC-Derived Retinal Organoids

Autor: Giuliana Gagliardi, Karim Ben M'Barek, Antoine Chaffiol, Amélie Slembrouck-Brec, Jean-Baptiste Conart, Céline Nanteau, Oriane Rabesandratana, José-Alain Sahel, Jens Duebel, Gael Orieux, Sacha Reichman, Olivier Goureau

Publikováno v: Stem Cell Reports, Vol 11, Iss 3, Pp 665-680 (2018)

Summary: Photoreceptor degenerative diseases are a major cause of blindness for which cell replacement is one of the most encouraging strategies. For stem cell-based therapy using human induced pluripotent stem cells (hiPSCs), it is crucial to obtain

Externí odkaz: https://doaj.org/article/832558c026a64479877cad4a7e382e28

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Akademický článek

Generation of human induced pluripotent stem cell lines from a patient with ITM2B-related retinal dystrophy and a non mutated brother

Autor: Juliette Wohlschlegel, Camille Letellier, Bingqian Liu, Cécile Méjécase, Amélie Slembrouck-Brec, Christel Condroyer, Christelle Michiels, José-Alain Sahel, Sacha Reichman, Christina Zeitz, Olivier Goureau, Isabelle Audo

Publikováno v: Stem Cell Research, Vol 41, Iss , Pp - (2019)

Human induced pluripotent stem cell (iPSC) lines were generated from fibroblasts of a patient affected with an autosomal dominant retinal dystrophy carrying the mutation c.782A>C, p.Glu261Ala in ITM2B and from an unaffected brother. Three different i

Externí odkaz: https://doaj.org/article/773cc77a70734b14a4f8c98a98c55f03

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Akademický článek

Reprogramming of Adult Retinal Müller Glial Cells into Human-Induced Pluripotent Stem Cells as an Efficient Source of Retinal Cells

Autor: Amélie Slembrouck-Brec, Amélie Rodrigues, Oriane Rabesandratana, Giuliana Gagliardi, Céline Nanteau, Stéphane Fouquet, Gilles Thuret, Sacha Reichman, Gael Orieux, Olivier Goureau

Publikováno v: Stem Cells International, Vol 2019 (2019)

The reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) has broad applications in regenerative medicine. The generation of self-organized retinal structures from these iPSCs offers the opportunity to study retinal developme

Externí odkaz: https://doaj.org/article/028b997cd5304c089fbd690b8b3935b1

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Dynamic Full-Field Optical Coherence Tomography module adapted to commercial microscopes for longitudinal in vitro cell culture study

Autor: Tual Monfort, Salvatore Azzollini, Jeremy Brogard, Marilou Clémençon, Amélie Slembrouck Brec, Valérie Forster, Serge Picaud, Olivier Goureau, Sacha Reichman, Olivier Thouvenin, Kate Grieve

Dynamic full-field optical coherence tomography (D-FFOCT) has recently emerged as a label-free imaging tool, capable of resolving cell types and organelles within 3D live samples, whilst monitoring their activity at tens of milliseconds resolution. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e2056a0a770045f0d967826f7afe60
https://doi.org/10.21203/rs.3.rs-2624414/v1

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Modeling PRPF31 retinitis pigmentosa using retinal pigment epithelium and organoids combined with gene augmentation rescue

Publikováno v: NPJ Regenerative medicine
NPJ Regenerative medicine, 2022, 7, pp.39. ⟨10.1038/s41536-022-00235-6⟩

Mutations in the ubiquitously expressedpre-mRNA processing factor(PRPF)31gene, one of the most common causes of dominant form of Retinitis Pigmentosa (RP), lead to a retina-specific phenotype. It is uncertain which retinal cell types are affected and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d0163641b58e202e3e801bc9dc3954
https://pubmed.ncbi.nlm.nih.gov/35974011

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