Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amélie I. Velghe"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Somatic point mutations of the FOXO1 transcription factor were reported in non-Hodgkin lymphoma including diffuse large B-cell lymphoma, follicular lymphoma and Burkitt lymphoma. These alterations were associated with a poor prognosis and re
Externí odkaz:
https://doaj.org/article/b2bb925e220f47229c85166c558a5977
Autor:
Carmen P. Montano-Almendras, Ahmed Essaghir, Hélène Schoemans, Inci Varis, Laura A. Noël, Amélie I. Velghe, Dominique Latinne, Laurent Knoops, Jean-Baptiste Demoulin
Publikováno v:
Haematologica, Vol 97, Iss 7 (2012)
Background ETV6-PDGFRB (also called TEL-PDGFRB) and FIP1L1-PDGFRA are receptor-tyrosine kinase fusion genes that cause chronic myeloid malignancies associated with hypereosinophilia. The aim of this work was to gain insight into the mechanisms whereb
Externí odkaz:
https://doaj.org/article/a5725eee73ea45ff9dd63cdabf195f62
Autor:
Anatoly S. Urban, Amélie I. Velghe, Roman G. Efremov, Bojan Zagrovic, Andrey S. Kuznetsov, Eduard V. Bocharov, Olga V. Bocharova, Anton A. Polyansky, Alexander S. Arseniev, Jean-Baptiste Demoulin
Publikováno v:
Biochimica et biophysica acta. General subjects, Vol. 1863, no.1, p. 82-95 (2019)
Single-point mutations in the transmembrane (TM) region of receptor tyrosine kinases (RTKs) can lead to abnormal ligand-independent activation. We use a combination of computational modeling, NMR spectroscopy and cell experiments to analyze in detail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1793a64e4ca2a9afdc7d65e0faa43b
https://doi.org/10.1016/j.bbagen.2018.09.011
https://doi.org/10.1016/j.bbagen.2018.09.011
Autor:
Maria Debiec-Rychter, Bénédicte Brichard, Ann Van Damme, Raf Sciot, Amélie I. Velghe, Miikka Vikkula, Florence A. Arts, Guillaume Dachy, Christine Galant, Hélène Poirel, Laura A. Noël, Raphaël Helaers, Nisha Limaye, Marleen Renard, Audrey de Rocca Serra, Jean-Baptiste Demoulin
Publikováno v:
Human Molecular Genetics. 26:1801-1810
Infantile myofibromatosis is one of the most prevalent soft tissue tumors of infancy and childhood. Multifocal nodules with visceral lesions are associated with a poor prognosis. A few familial cases have been linked to mutations in various genes inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0eca6a418efc4bc65d26e12f4cfd67
https://doi.org/10.1093/hmg/ddx081
https://doi.org/10.1093/hmg/ddx081
Autor:
Donatienne Tyteca, Nicolas Dif, Audrey de Rocca Serra, Amélie I. Velghe, Yvan Larondelle, Jean-Baptiste Demoulin, Chloé Bonnineau, Alexandra Coomans De Brachene
Publikováno v:
F E B S Open Bio, Vol. 7, no.3, p. 414-423 (march 2017)
F E B S Open Bio, Vol. 7, no. 3, p. 414-423 (2017)
FEBS Open Bio
F E B S Open Bio, Vol. 7, no. 3, p. 414-423 (2017)
FEBS Open Bio
Stearoyl-coenzyme A desaturase (SCD) catalyzes the Δ9-cis desaturation of saturated fatty acids (SFA) to generate monounsaturated fatty acids (MUFA). This enzyme is highly up-regulated by platelet-derived growth factor (PDGF) in human fibroblasts. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8759e04ed4ba83ff2de6f4428c979a
https://hdl.handle.net/2078.1/183362
https://hdl.handle.net/2078.1/183362
Autor:
Laura A. Noël, Bénédicte Brichard, Jean-Baptiste Demoulin, An Van Damme, Miikka Vikkula, Marleen Renard, Maria Debiec-Rychter, Raphaël Helaers, Nisha Limaye, Amélie I. Velghe, Hélène Poirel, Raf Sciot, Florence A. Arts, Christine Galant
Publikováno v:
Cancer Research. 77:534-534
Myofibromas and infantile myofibromatosis are among the most prevalent soft tissue tumors of infancy and childhood. They are characterized by the presence of solitary or multiple nodules in the skin, subcutaneous soft tissues, bones, muscles and visc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e60173a2469c0a1158c1033fec077b2f
https://doi.org/10.1158/1538-7445.am2017-534
https://doi.org/10.1158/1538-7445.am2017-534
Autor:
Jean-Baptiste Demoulin, Monique Stevens, Florence A. Arts, Ahmed Essaghir, Amélie I. Velghe, Jean-Christophe Renauld
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine, Vol. 19, no.1, p. 239-248 (2015)
Journal of Cellular and Molecular Medicine, Vol. 19, no.1, p. 239-248 (2015)
Platelet-derived growth factors (PDGF) bind to two related receptor tyrosine kinases, which are encoded by the PDGFRA and PDGFRB genes. Recently, heterozygous PDGFRB mutations have been described in patients diagnosed with idiopathic basal ganglia ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ce1788bcebd57aff4155f939d4379b
https://pubmed.ncbi.nlm.nih.gov/25292412
https://pubmed.ncbi.nlm.nih.gov/25292412
Autor:
Ahmed Essaghir, Laura A. Noël, Laurent Knoops, Carmen P. Montano-Almendras, Amélie I. Velghe, Hélène Schoemans, Inci Varis, Jean-Baptiste Demoulin, Dominique Latinne
BACKGROUND: ETV6-PDGFRB (also called TEL-PDGFRB) and FIP1L1-PDGFRA are receptor-tyrosine kinase fusion genes that cause chronic myeloid malignancies associated with hypereosinophilia. The aim of this work was to gain insight into the mechanisms where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56be48c8ed6523bbb50392974b932c9
https://europepmc.org/articles/PMC3396679/
https://europepmc.org/articles/PMC3396679/