Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Amélia Galdino Ribeiro"'
Autor:
Keriolaine Lima dos Santos, Sinara Mônica Vitalino de Almeida, Josival Emanuel Ferreira Alves, Iris Trindade Tenório Jacob, Rafael David Souto de Azevedo, Cindy Juliane da Silva Ferreira, Jéssica Celerino dos Santos, Maria do Carmo Alves de Lima, José Cleberson Santos Soares, Amélia Galdino Ribeiro
Publikováno v:
Medicinal Chemistry Research. 30:1469-1495
Albumin is an abundant protein in nature with several biological functions. In the human body, both in health and in illness, its transport function is highlighted by the binding to medicinal drugs and consequent distribution in the bloodstream to th
Autor:
Thais de Freitas Souza, Josival Emanuel Ferreira Alves, Amélia Galdino Ribeiro, Jamerson Ferreira de Oliveira, Luiz Bezerra de Carvalho Júnior, Sinara Mônica Vitalino de Almeida, Ricardo Olímpio de Moura, Maria do Carmo Alves de Lima, Túlio Ricardo Couto de Lima Souza, Francivaldo Araújo da Silva Filho
Publikováno v:
International Journal of Biological Macromolecules. 138:582-589
In the present study, acridine-thiosemicarbazones (ATD) derivatives were tested for their interaction properties with BSA through UV–Vis absorption and fluorescence spectroscopic studies. Both hyperchromic and hypochromic effects, as well as red or
Autor:
Ricardo Olímpio de Moura, Maria Carolina Accioly Brelaz de Castro, Amanda P. B. Albuquerque, Sinara Mônica Vitalino de Almeida, Mariane Cajubá de Britto Lira Nogueira, Luiz Bezerra de Carvalho Júnior, Maria do Carmo Alves de Lima, Túlio Ricardo Couto de Lima Souza, Jamerson Ferreira de Oliveira, Keriolaine Lima dos Santos, Amélia Galdino Ribeiro, Valéria Rêgo Alves Pereira, Aline Caroline da Silva
Publikováno v:
European journal of medicinal chemistry. 182
Twelve 2-(quinolin-4-ylmethylene) hydrazinecarbothioamide derivatives were synthetized and their biological properties were investigated, among which, the ability to interact with DNA and BSA through UV–Vis absorption, fluorescence, Circular Dichro
Autor:
Amélia Galdino Ribeiro, Maria do Carmo Alves de Lima, Keriolaine Lima dos Santos, Cindy Juliane da Silva Ferreira, José Cleberson Santos Soares, Jamerson Ferreira de Oliveira, Iris Trindade Tenório Jacob, Jéssica Celerino dos Santos, Josival Emanuel Ferreira Alves, Luiz Bezerra de Carvalho Júnior, Sinara Mônica Vitalino de Almeida
Publikováno v:
Bioorganic & Medicinal Chemistry
Graphical abstract
Urgent treatments, in any modality, to fight SARS-CoV-2 infections are desired by society in general, by health professionals, by Estate-leaders and, mainly, by the scientific community, because one thing is certain amidst the
Urgent treatments, in any modality, to fight SARS-CoV-2 infections are desired by society in general, by health professionals, by Estate-leaders and, mainly, by the scientific community, because one thing is certain amidst the
Autor:
Amélia Galdino Ribeiro, Ricardo Olímpio de Moura, Maria do Carmo Alves de Lima, Ana Lúcia Tasca Gois Ruiz, João Carvalho, Jamerson Ferreira de Oliveira, Júlia Furtado Campos, Anekécia Lauro da Silva, Débora Barbosa Vendramini-Costa, Jorge L. Neves, Cezar Augusto da Cruz Amorim
Publikováno v:
European Journal of Medicinal Chemistry. 104:148-156
A series of thiophene-2-thiosemicarbazones derivatives ( 5 – 14 ) was synthesized, characterized and evaluated for their antitumor activity. They were tested in vitro against human tumor cell lines through the colorimetric method. The results revea
Autor:
Túlio Ricardo Couto de Lima Souza, Sinara Mônica Vitalino de Almeida, Ricardo Olímpio de Moura, Jamerson Ferreira de Oliveira, Amélia Galdino Ribeiro, Miguel Ângelo Santos Pinheiro Segundo, Maria do Carmo Alves de Lima, Rawny Galdino Gouveia
Publikováno v:
Bioorganicmedicinal chemistry. 26(22)
Nine new spiroacridine derivatives were synthetized by introducing cyano-N-acylhydrazone group between the acridine and phenyl-substituted rings followed by spontaneous cyclization. The new compounds were assayed for their DNA binding properties, hum
Autor:
Jamerson Ferreira de Oliveira, Josival Emanuel Ferreira Alves, Sinara Mônica Vitalino de Almeida, Amélia Galdino Ribeiro, Maria do Carmo Alves de Lima, Geilza Carla de Lima Silva, Luiz Bezerra de Carvalho, Eduardo Isidoro Carneiro Beltrão
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 96
DNA is considered one of the most promising targets of molecules with anticancer activity potential. Its key role in various cell division mechanisms, which commands the intense multiplication of tumor cells, is considered in studies with compounds w