Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Amédée des Georges"'
Autor:
Stine Sofie Frank Lende, Nanna Møller Barnkob, Randi Westh Hansen, Harsh Bansia, Mike Vestergaard, Frederik Holm Rothemejer, Anne Worsaae, Deijona Brown, Maria Lange Pedersen, Anna Halling Folkmar Rahimic, Anna Karina Juhl, Torben Gjetting, Lars Østergaard, Amédée Des Georges, Laurent-Michel Vuillard, Mariane Høgsbjerg Schleimann, Klaus Koefoed, Martin Tolstrup
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291131 (2023)
Despite development of effective SARS-CoV-2 vaccines, a sub-group of vaccine non-responders depends on therapeutic antibodies or small-molecule drugs in cases of severe disease. However, perpetual viral evolution has required continuous efficacy moni
Externí odkaz:
https://doaj.org/article/b7a3f6670264473b8d148355f22c7104
Autor:
Linda Celeste Montemiglio, Claudia Testi, Pierpaolo Ceci, Elisabetta Falvo, Martina Pitea, Carmelinda Savino, Alessandro Arcovito, Giovanna Peruzzi, Paola Baiocco, Filippo Mancia, Alberto Boffi, Amédée des Georges, Beatrice Vallone
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
The human transferrin receptor 1 (CD71) is a transmembrane protein responsible for iron uptake. Here the authors present the 3.9 Å resolution cryo-EM structure of the CD71 ectodomain-human ferritin (H-Ft) complex and find that H-Ft binds a CD71 regi
Externí odkaz:
https://doaj.org/article/61472d52cca641faa05071392f71cf5c
Autor:
Lorenzo Calisti, Matilde Cardoso Trabuco, Alberto Boffi, Claudia Testi, Linda Celeste Montemiglio, Amédée des Georges, Irene Benni, Andrea Ilari, Bartłomiej Taciak, Maciej Białasek, Tomasz Rygiel, Magdalena Król, Paola Baiocco, Alessandra Bonamore
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201859 (2018)
Ferritin H-homopolymers have been extensively used as nanocarriers for diverse applications in the targeted delivery of drugs and imaging agents, due to their unique ability to bind the transferrin receptor (CD71), highly overexpressed in most tumor
Externí odkaz:
https://doaj.org/article/dd405814a8d5434c9057374b1ebcf726
Autor:
Juliette Fedry, Joana Silva, Mihajlo Vanevic, Stanley Fronik, Yves Mechulam, Emmanuelle Schmitt, Amédée des Georges, William Faller, Friedrich Förster
Publikováno v:
bioRxiv
Aberrantly slow mRNA translation leads to ribosome stalling and subsequent collision with the trailing neighbor. Ribosome collisions have recently been shown to act as stress sensors in the cell, with the ability to trigger stress responses balancing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03904652e9ae1185e37e4618905568fe
https://europepmc.org/articles/PMC10055323/
https://europepmc.org/articles/PMC10055323/
Autor:
Tara C. Marcink, Thomas Kicmal, Emily Armbruster, Zhening Zhang, Gillian Zipursky, Kate L. Golub, Mohab Idris, Jonathan Khao, Jennifer Drew-Bear, Gael McGill, Tom Gallagher, Matteo Porotto, Amédée des Georges, Anne Moscona
Publikováno v:
Science advances. 8(33)
SARS-CoV-2 cell entry is completed after viral spike (S) protein–mediated membrane fusion between viral and host cell membranes. Stable prefusion and postfusion S structures have been resolved by cryo–electron microscopy and cryo–electron tomog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c0dd7eb0cf7e1adfe8f67a97eb05eb
https://pubmed.ncbi.nlm.nih.gov/35984891
https://pubmed.ncbi.nlm.nih.gov/35984891
Autor:
Ali Dashti, Ghoncheh Mashayekhi, Mrinal Shekhar, Danya Ben Hail, Salah Salah, Peter Schwander, Amedee des Georges, Abhishek Singharoy, Joachim Frank, Abbas Ourmazd
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
There is a great interest in retrieving functional pathways from cryo-EM single-particle data. Here, the authors present an approach that combines cryo-EM with advanced data-analytical methods and molecular dynamics simulations to reveal the function
Externí odkaz:
https://doaj.org/article/a9730a6e4420466a99ccf8fd2dbeaec2
Human parainfluenza virus fusion complex glycoproteins imaged in action on authentic viral surfaces.
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008883 (2020)
Infection by human parainfluenza viruses (HPIVs) causes widespread lower respiratory diseases, including croup, bronchiolitis, and pneumonia, and there are no vaccines or effective treatments for these viruses. HPIV3 is a member of the Respirovirus s
Externí odkaz:
https://doaj.org/article/62adb3c562f24143b7cad3b3da62facc
Publikováno v:
Membranes, Vol 11, Iss 11, p 849 (2021)
Mechanosensitive channels respond to mechanical forces exerted on the cell membrane and play vital roles in regulating the chemical equilibrium within cells and their environment. High-resolution structural information is required to understand the g
Externí odkaz:
https://doaj.org/article/d6ef261896024b6c834f3ab697fff4a4
Autor:
Jillian Chase, Andrew Catalano, Alex J Noble, Edward T Eng, Paul DB Olinares, Kelly Molloy, Danaya Pakotiprapha, Martin Samuels, Brian Chait, Amedee des Georges, David Jeruzalmi
Publikováno v:
eLife, Vol 7 (2018)
Assembly of bacterial ring-shaped hexameric replicative helicases on single-stranded (ss) DNA requires specialized loading factors. However, mechanisms implemented by these factors during opening and closing of the helicase, which enable and restrict
Externí odkaz:
https://doaj.org/article/c5e7063e0b1b4a42a358ecdbc1d0425f
Autor:
Sho Iketani, Ryan C. Shean, Marion Ferren, Negar Makhsous, Dolly B. Aquino, Amedee des Georges, Bert Rima, Cyrille Mathieu, Matteo Porotto, Anne Moscona, Alexander L. Greninger
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
IMPORTANCE Human parainfluenza virus 3 is an important cause of morbidity and mortality among infants, the immunocompromised, and the elderly. Using deep genomic sequencing of HPIV-3-positive clinical material and its subsequent viral isolate, we dis
Externí odkaz:
https://doaj.org/article/116787510a404c218ec29e3d5ebc31b9