Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

Autor: Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Wright DJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Day FR; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Trajanoska K; Department of Internal Medicine, Erasmus Medical Center, 3015 CE Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015 CE Rotterdam, The Netherlands., Joshi PK; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AB, UK., Morris JA; Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, Canada QC H3T 1E2.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3G 0B1., Matteini AM; Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA., Garton FC; Queensland Brain Institute, University of Queensland, St Lucia, Queensland 4072, Australia., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Oskolkov N; Lund University Diabetes Center, Department of Clinical Sciences, Diabetes and Endocrinology, Skånes University Hospital, 222 41 Lund, Sweden., Thalamuthu A; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, New South Wales 2031, Australia., Mangino M; Department of Twin Research &Genetic Epidemiology, Kings College London, London SE1 7EH, UK.; NIHR Biomedical Research Centre at Guy's and St. Thomas' NHS Foundation Trust, London SE1 9RT, UK., Liu J; Department of Epidemiology, Erasmus Medical Center, 3015 CE Rotterdam, The Netherlands., Demirkan A; Department of Epidemiology, Erasmus Medical Center, 3015 CE Rotterdam, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Lek M; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Maryland 02114, USA.; Harvard Medical School, Boston, Maryland 02115, USA., Xu L; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Maryland 02114, USA.; Harvard Medical School, Boston, Maryland 02115, USA., Wang G; Centre for Sport and Exercise Science and Medicine (SESAME), University of Brighton, Eastbourne BN20 7SN, UK., Oldmeadow C; Hunter Medical Research Institute, Newcastle, New South Wales 2305, Australia., Gaulton KJ; Department of Pediatrics, University of California San Diego, La Jolla, California 92093, USA., Lotta LA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Miyamoto-Mikami E; Japan Society for the Promotion of Science, Tokyo 102-0083, Japan.; Department of Sports and Life Science, National Institute of Fitness and Sports, Kanoya, Kagoshima 891-2393, Japan., Rivas MA; Department of Biomedical Data Sciences, Stanford University, Stanford, California 94305, USA.; BROAD Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA., White T; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Loh PR; BROAD Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA., Aadahl M; Research Centre for Prevention and Health, Capital Region of Denmark, Glostrup University Hospital, DK-2600 Glostrup, Denmark., Amin N; Department of Epidemiology, Erasmus Medical Center, 3015 CE Rotterdam, The Netherlands., Attia JR; Hunter Medical Research Institute, Newcastle, New South Wales 2305, Australia.; Faculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales 2308, Australia.; John Hunter Hospital, New Lambton, New South Wales 2305, Australia., Austin K; Centre for Sport and Exercise Science and Medicine (SESAME), University of Brighton, Eastbourne BN20 7SN, UK., Benyamin B; Queensland Brain Institute, University of Queensland, St Lucia, Queensland 4072, Australia.; Institute for Molecular Bioscience, University of Queensland, St Lucia, Queensland 4072, Australia., Brage S; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Cheng YC; Division of Endocrinology Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA., Cięszczyk P; Faculty of Physical Education, Gdańsk University of Physical Education and Sport, 80-336 Gdańsk, Poland., Derave W; Department of Movement and Sports Sciences, Ghent University, 9000 Ghent, Belgium., Eriksson KF; Lund University Diabetes Center, Department of Clinical Sciences, Diabetes and Endocrinology, Skånes University Hospital, 222 41 Lund, Sweden., Eynon N; Institute of Sport, Exercise &Active Living (ISEAL), Victoria University, Melbourne, Victoria 8001, Australia.; Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, Victoria 3052, Australia., Linneberg A; Research Centre for Prevention and Health, Capital Region of Denmark, Glostrup University Hospital, DK-2600 Glostrup, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, 2600 Glostrup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark., Lucia A; Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Madrid, Spain.; Research Institute 'i+12', Hospital Universitario 12 de Octubre, 28041 Madrid, Spain., Massidda M; Department of Life and Environmental Sciences, University of Cagliari, 09124 Cagliari, Italy., Mitchell BD; Division of Endocrinology Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland 21201, USA., Miyachi M; National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo 162-8636, Japan., Murakami H; National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo 162-8636, Japan., Padmanabhan S; British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK., Pandey A; Target Sciences, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA., Papadimitriou I; Institute of Sport, Exercise &Active Living (ISEAL), Victoria University, Melbourne, Victoria 8001, Australia., Rajpal DK; Target Sciences, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA., Sale C; Musculoskeletal Physiology Research Group, Sport, Health and Performance Enhancement (SHAPE) Research Centre, Nottingham Trent University, Nottingham NG1 4FQ, UK., Schnurr TM; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Sessa F; Department of Clinical and Experimental Medicine, Medical Genetics, University of Foggia, 71122 Foggia FG, Italy., Shrine N; Department of Health Sciences, University of Leicester, Leicester LE1 7RH, UK.; National Institute for Health Research, Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester LE1 7RH, UK.; National Institute for Health Research, Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK., Varley I; Musculoskeletal Physiology Research Group, Sport, Health and Performance Enhancement (SHAPE) Research Centre, Nottingham Trent University, Nottingham NG1 4FQ, UK., Wain LV; Department of Health Sciences, University of Leicester, Leicester LE1 7RH, UK.; National Institute for Health Research, Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK., Wray NR; Queensland Brain Institute, University of Queensland, St Lucia, Queensland 4072, Australia.; Institute for Molecular Bioscience, University of Queensland, St Lucia, Queensland 4072, Australia., Lindgren CM; BROAD Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.; The Big Data Institute, University of Oxford, Oxford OX3 7BN, UK.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., MacArthur DG; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Maryland 02114, USA.; BROAD Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA., Waterworth DM; Target Sciences, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA., McCarthy MI; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LE, UK.; NIHR Oxford Biomedical Research Centre, Oxford OX3 7LE, UK., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Khaw KT; Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0SR, UK., Kiel DP; Harvard Medical School, Boston, Maryland 02115, USA.; Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131, USA.; Department of Medicine, Beth Israel Deaconess Medical Centre, Boston, Massachusetts 02215, USA., Pitsiladis Y; Centre for Sport and Exercise Science and Medicine (SESAME), University of Brighton, Eastbourne BN20 7SN, UK., Fuku N; Graduate School of Health and Sports Science, Juntendo University, Chiba 270-1695, Japan., Franks PW; Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Skånes University Hospital, 222 41 Lund, Sweden.; Public Health and Clinical Medicine, Section for Medicine, Umeå University, 901 87 Umeå, Sweden.; Biobank Research, Umeå University, 901 87 Umeå, Sweden., North KN; Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, Victoria 3052, Australia., van Duijn CM; Department of Epidemiology, Erasmus Medical Center, 3015 CE Rotterdam, The Netherlands., Mather KA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, New South Wales 2031, Australia., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, 5230 Odense M, Denmark., Hansson O; Lund University Diabetes Center, Department of Clinical Sciences, Diabetes and Endocrinology, Skånes University Hospital, 222 41 Lund, Sweden., Spector T; Department of Twin Research &Genetic Epidemiology, Kings College London, London SE1 7EH, UK., Murabito JM; Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, Massachusetts 02118, USA.; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts 01702, USA., Richards JB; Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, Canada QC H3T 1E2.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3G 0B1.; Department of Twin Research &Genetic Epidemiology, Kings College London, London SE1 7EH, UK.; Department of Medicine, McGill University, Montreal, Quebec, Canada H3G 1A4., Rivadeneira F; Department of Internal Medicine, Erasmus Medical Center, 3015 CE Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015 CE Rotterdam, The Netherlands., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Perry JRB; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK.

Publikováno v: Nature communications [Nat Commun] 2017 Jul 12; Vol. 8, pp. 16015. Date of Electronic Publication: 2017 Jul 12.

The complex genetics of gait speed: genome-wide meta-analysis approach.

Autor: Ben-Avraham D; Department of Medicine and Genetics Albert Einstein College of Medicine, Bronx, NY 10461, USA., Karasik D; Institute for Aging Research, Hebrew SeniorLife, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02131, USA.; Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel., Verghese J; Integrated Divisions of Cognitive & Motor Aging (Neurology) and Geriatrics (Medicine), Montefiore-Einstein Center for the Aging Brain, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Lunetta KL; The National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA., Eicher JD; The National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA.; Population Sciences Branch, National Heart Lung and Blood Institute, Framingham, MA 01702, USA., Vered R; Psychology Department, University of Haifa, Haifa, Israel., Deelen J; Molecular Epidemiology, Leiden University Medical Center, Leiden, Netherlands.; Max Planck Institute for Biology of Ageing, Köln, Germany., Arnold AM; Department of Biostatistics, University of Washington, Seattle, WA 98115, USA., Buchman AS; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60614, USA., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore MD 21224, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI 48104, USA., Nethander M; Bioinformatics Core Facility, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Fornage M; The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Adams HH; Department of Epidemiology, Erasmus MC, Rotterdam, Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, Netherlands., Matteini AM; Division of Geriatric Medicine, Johns Hopkins Medical Institutes, Baltimore, MD 21224, USA., Callisaya ML; Medicine, Peninsula Health, Peninsula Clinical School, Central Clinical School, Frankston, Melbourne, Victoria, Australia.; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia., Smith AV; Icelandic Heart Association, Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland., Yu L; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60614, USA., De Jager PL; Broad Institute of Harvard and MIT, Cambridge, Harvard Medical School, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA., Evans DA; Rush Institute for Healthy Aging and Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA., Gudnason V; Icelandic Heart Association, Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland., Hofman A; Department of Epidemiology, Erasmus MC, Rotterdam, Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Corley J; Department of Psychology, University of Edinburgh, Edinburgh, UK., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, MD 20892, USA., Knopman DS; Mayo Clinic, Rochester, MN 55905, USA., Parimi N; California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA., Turner ST; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA., Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy., Beekman M; Molecular Epidemiology, Leiden University Medical Center, Leiden, Netherlands., Gutman D; Department of Human Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel., Sharvit L; Department of Human Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel., Mooijaart SP; Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherland., Liewald DC; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Houwing-Duistermaat JJ; Genetical Statistics, Leiden University Medical Center, Leiden, Netherland. Department of Statistics, University of Leeds, Leeds, UK., Ohlsson C; Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska, Academy, University of Gothenburg, Gothenburg, Sweden., Moed M; Molecular Epidemiology, Leiden University Medical Center, Leiden, Netherlands., Verlinden VJ; Department of Epidemiology, Erasmus MC, Rotterdam, Netherlands., Mellström D; Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska, Academy, University of Gothenburg, Gothenburg, Sweden., van der Geest JN; Department of Neuroscience, Erasmus MC, Rotterdam, Netherlands., Karlsson M; Clinical and Molecular Osteoporosis Research Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden., Hernandez D; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA., McWhirter R; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia., Liu Y; Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University, Winston-Salem, NC 27109, USA., Thomson R; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.; School of Computing, Engineering and Mathematics, University of Western Sydney, Sydney, Australia., Tranah GJ; California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA., Uitterlinden AG; Department of Internal Medicine, Erasmus MC, and Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, The Netherlands., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI 48104, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Johnson AD; The National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA.; Population Sciences Branch, National Heart Lung and Blood Institute, Framingham, MA 01702, USA., Ikram MA; Department of Epidemiology, Erasmus MC, Rotterdam, Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, Netherlands., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60614, USA., Cummings SR; California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA., Deary IJ; Department of Psychology, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, MD 20892, USA., Kardia SL; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA., Mosley TH; University of Mississippi Medical Center, Jackson, MS 39216, USA., Srikanth VK; Medicine, Peninsula Health, Peninsula Clinical School, Central Clinical School, Frankston, Melbourne, Victoria, Australia.; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia., Windham BG; University of Mississippi Medical Center, Jackson, MS 39216, USA., Newman AB; Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA., Walston JD; Division of Geriatric Medicine, Johns Hopkins Medical Institutes, Baltimore, MD 21224, USA., Davies G; Department of Psychology, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Evans DS; California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA., Slagboom EP; Molecular Epidemiology, Leiden University Medical Center, Leiden, Netherlands., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore MD 21224, USA., Kiel DP; Institute for Aging Research, Hebrew SeniorLife, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02131, USA.; Broad Institute of Harvard and MIT, Boston, MA 02131, USA.; Co senior authors., Murabito JM; The National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA.; Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA.; Co senior authors., Atzmon G; Department of Medicine and Genetics Albert Einstein College of Medicine, Bronx, NY 10461, USA.; Department of Human Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel.; Co senior authors.

Publikováno v: Aging [Aging (Albany NY)] 2017 Jan 10; Vol. 9 (1), pp. 209-246.

Association Between Mortality and Heritability of the Scale of Aging Vigor in Epidemiology.

Autor: Sanders JL; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania., Singh J; Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania., Minster RL; Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania., Walston JD; Department of Medicine, Johns Hopkins University, Baltimore, Maryland., Matteini AM; Department of Medicine, Johns Hopkins University, Baltimore, Maryland., Christensen K; Department of Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense, Denmark., Mayeux R; Department of Neurology, Columbia University, New York, New York., Borecki IB; Division of Statistical Genetics, Washington University in St. Louis, St. Louis, Missouri., Perls T; Department of Medicine, Boston University, Boston, Massachusetts., Newman AB; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.

Publikováno v: Journal of the American Geriatrics Society [J Am Geriatr Soc] 2016 Aug; Vol. 64 (8), pp. 1679-83. Date of Electronic Publication: 2016 Jun 13.

Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index.

Autor: Minster RL; Department of Human Genetics and., Sanders JL; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania., Singh J; Department of Human Genetics and., Kammerer CM; Department of Human Genetics and., Barmada MM; Department of Human Genetics and., Matteini AM; Division of Geriatric Medicine and Gerontology, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Zhang Q; Division of Statistical Genomics, School of Medicine, Washington University in St. Louis, Missouri., Wojczynski MK; Division of Statistical Genomics, School of Medicine, Washington University in St. Louis, Missouri., Daw EW; Division of Statistical Genomics, School of Medicine, Washington University in St. Louis, Missouri., Brody JA; Cardiovascular Health Research Unit, Department of Medicine and., Arnold AM; Department of Biostatistics, University of Washington, Seattle., Lunetta KL; Department of Biostatistics, Boston University School of Public Health, Massachusetts., Murabito JM; National Heart, Lung and Blood Institute Framingham Heart Study, Massachusetts. Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Massachusetts., Christensen K; Department of Epidemiology, Institute of Public Health, University of Southern Denmark, Odense., Perls TT; Section of Geriatrics, Department of Medicine, Boston University, Boston School of Medicine and Boston Medical Center, Massachusetts., Province MA; Division of Statistical Genomics, School of Medicine, Washington University in St. Louis, Missouri., Newman AB; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania. newmana@edc.pitt.edu.

Publikováno v: The journals of gerontology. Series A, Biological sciences and medical sciences [J Gerontol A Biol Sci Med Sci] 2015 Aug; Vol. 70 (8), pp. 1003-8. Date of Electronic Publication: 2015 Mar 10.

Association of mitochondrial DNA levels with frailty and all-cause mortality.

Autor: Ashar FN; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA., Moes A; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA., Moore AZ; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA., Grove ML; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, 7000 Fannin St, Houston, TX 77030, USA., Chaves PHM; Benjamin Leon Center for Geriatric Research and Education and Department of Medicine, Florida International University, 11200 SW 8 St, Miami, FL 33174, USA., Coresh J; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA., Newman AB; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 4200 Fifth Ave, Pittsburgh, PA 15260, USA., Matteini AM; Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA., Bandeen-Roche K; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA., Boerwinkle E; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, 7000 Fannin St, Houston, TX 77030, USA., Walston JD; Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA., Arking DE; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA.; Department of Medicine, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA.

Publikováno v: Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2015 Feb; Vol. 93 (2), pp. 177-186. Date of Electronic Publication: 2014 Dec 04.