Further characterization of factor VIII-deficient mice created by gene targeting: RNA and protein studies

Autor: Bi L, Sarkar R, Thierry Naas, Am, Lawler, Pain J, Sl, Shumaker, Bedian V, Hh, Kazazian

Publikováno v: Europe PubMed Central

Previously we created two strains of factor VIII-deficient mice by insertion of a neo gene into (1) the 3′ end of exon 16 and (2) exon 17 of the factor VIII gene. Affected mice of both strains have no plasma factor VIII activity, yet are healthy wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cb80993cde86aea7ec7a2a89ba6560
https://doi.org/10.1182/blood.v88.9.3446.bloodjournal8893446

Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality.

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Autor: Zhao R; Department of Molecular Biology and Genetics, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland, 21205, USA., Lawler AM, Lee SJ

Publikováno v: Developmental biology [Dev Biol] 1999 Aug 01; Vol. 212 (1), pp. 68-79.

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Autor: Litingtung Y; Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Lawler AM, Sebald SM, Lee E, Gearhart JD, Westphal H, Corden JL

Publikováno v: Molecular & general genetics : MGG [Mol Gen Genet] 1999 Feb; Vol. 261 (1), pp. 100-5.