How much fat is necessary to optimize lumefantrine oral bioavailability?

Autor: Anna Annerberg, Kasia Stepniewska, Nicholas J. White, Elizabeth A. Ashley, François Nosten, Am Kham, Pratap Singhasivanon, Niklas Lindegardh, Al Brockman

Publikováno v: Tropical Medicine & International Health. 12:195-200

Summary Background Artemether–lumefantrine (AL) is the only fixed, artemisinin-based combination antimalarial drug which is registered internationally and deployed on a large scale. Absorption of the hydrophobic lipophilic lumefantrine component va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7709a60f466847a2830460048f0be944
https://doi.org/10.1111/j.1365-3156.2006.01784.x

Artesunate versus artemether in combination with mefloquine for the treatment of multidrug-resistant falciparum malaria

Autor: Alan Brockman, François Nosten, Ric N. Price, Am Kham, Tan Chongsuphajaisiddhi, Christine Luxemburger, Nicholas J. White

Publikováno v: Transactions of the Royal Society of Tropical Medicine and Hygiene. 89:523-527

To compare the therapeutic efficacy of oral artesunate and artemether in combination with mefloquine for the treatment of multidrug resistant malaria, a trial was conducted in 540 adults and children on the Thai-Myanmar border. Three regimens were co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9c791ee6a5c34b305bd4449326f192
https://doi.org/10.1016/0035-9203(95)90094-2

Effects of malaria during pregnancy on infant mortality in an area of low malaria transmission

Autor: Thein Cho, Christine Luxemburger, Tan Chongsuphajaisiddhi, François Nosten, Am Kham, Rose McGready, Nicholas J. White, Linda Morison

Publikováno v: American journal of epidemiology. 154(5)

Malaria during pregnancy reduces birth weight, and low birth weight is a major determinant of infant mortality. The authors estimated the impact of malaria during pregnancy on infant mortality in a Karen population living in Thailand. Between 1993 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1866e87e9ec20f1ecb33c78f70a4f5
https://pubmed.ncbi.nlm.nih.gov/11532788

Adverse effects in patients with acute falciparum malaria treated with artemisinin derivatives

Autor: Rose McGready, L Phaipun, François Nosten, M. van Vugt, Am Kham, Nicholas J. White, Ric N. Price, F O ter Kuile, Tan Chongsuphajaisiddhi, Christine Luxemburger, Julie A. Simpson

Publikováno v: Scopus-Elsevier
Europe PubMed Central
American journal of tropical medicine and hygiene, 60(4), 547-555. American Society of Tropical Medicine and Hygiene

In prospective studies of acute uncomplicated, multidrug-resistant falciparum malaria on the western border of Thailand, the oral artemisinin derivatives were used alone in the treatment of 836 patients (artesunate 630, artemether 206), were combined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5fc6cd489e9fdb94b97471a2ad43f5
http://www.scopus.com/inward/record.url?eid=2-s2.0-0032960336&partnerID=MN8TOARS