Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Alzheimer Disease/metabolism"'
Autor:
Nadia Rosenberg, Maria Reva, Francesca Binda, Leonardo Restivo, Pauline Depierre, Julien Puyal, Marc Briquet, Yann Bernardinelli, Anne‐Bérengère Rocher, Henry Markram, Jean‐Yves Chatton
Publikováno v:
Glia, vol. 71, no. 4, pp. 957-973
Alzheimer's disease (AD) is becoming increasingly prevalent worldwide. It represents one of the greatest medical challenges as no pharmacologic treatments are available to prevent disease progression. Astrocytes play crucial functions within neuronal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f55053e7a0339af69a3954befb63d9
https://doi.org/10.1002/glia.24317
https://doi.org/10.1002/glia.24317
Autor:
Kommaddi, Reddy Peera
Publikováno v:
Kommaddi, R P 2023, ' Sex difference in evolution of cognitive decline : studies on mouse model and the Dominantly Inherited Alzheimer Network cohort ', Translational Psychiatry, vol. 13, no. 1, pp. 123 . https://doi.org/10.1038/s41398-023-02411-8
Women carry a higher burden of Alzheimer's disease (AD) compared to men, which is not accounted entirely by differences in lifespan. To identify the mechanisms underlying this effect, we investigated sex-specific differences in the progression of fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::ca51aa618388e65ac0752f665705874f
https://www.pure.ed.ac.uk/ws/files/344245877/s41398_023_02411_8.pdf
https://www.pure.ed.ac.uk/ws/files/344245877/s41398_023_02411_8.pdf
Autor:
Marine Denechaud, Sarah Geurs, Thomas Comptdaer, Séverine Bégard, Alejandro Garcia-Núñez, Louis-Adrien Pechereau, Thomas Bouillet, Yannick Vermeiren, Peter P. De Deyn, Romain Perbet, Vincent Deramecourt, Claude-Alain Maurage, Michiel Vanderhaegen, Sebastiaan Vanuytven, Bruno Lefebvre, Elke Bogaert, Nicole Déglon, Thierry Voet, Morvane Colin, Luc Buée, Bart Dermaut, Marie-Christine Galas
Publikováno v:
Progress in neurobiology
Progress in neurobiology 223 (2023)
PROGRESS IN NEUROBIOLOGY
Progress in neurobiology, 223
Progress in neurobiology, vol. 223, pp. 102386
Progress in neurobiology 223 (2023)
PROGRESS IN NEUROBIOLOGY
Progress in neurobiology, 223
Progress in neurobiology, vol. 223, pp. 102386
Multiple lines of evidence have linked oxidative stress, tau pathology and neuronal cell cycle re-activation to Alzheimer's disease (AD). While a prevailing idea is that oxidative stress-induced neuronal cell cycle reactivation acts as an upstream tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e268b1fec3551c4f90a3443453adf541
https://hdl.handle.net/10067/1929640151162165141
https://hdl.handle.net/10067/1929640151162165141
Autor:
Fangda Leng, Rainer Hinz, Steve Gentleman, Adam Hampshire, Melanie Dani, David J. Brooks, Paul Edison
Publikováno v:
Leng, F, Hinz, R, Gentleman, S, Hampshire, A, Dani, M, Brooks, D J & Edison, P 2022, ' Neuroinflammation is independently associated with brain network dysfunction in Alzheimer’s disease ', Molecular psychiatry . https://doi.org/10.1038/s41380-022-01878-z
Leng, F, Hinz, R, Gentleman, S, Hampshire, A, Dani, M, Brooks, D J & Edison, P 2023, ' Neuroinflammation is independently associated with brain network dysfunction in Alzheimer's disease ', Molecular Psychiatry, vol. 28, no. 3 . https://doi.org/10.1038/s41380-022-01878-z
Leng, F, Hinz, R, Gentleman, S, Hampshire, A, Dani, M, Brooks, D J & Edison, P 2023, ' Neuroinflammation is independently associated with brain network dysfunction in Alzheimer's disease ', Molecular Psychiatry, vol. 28, no. 3 . https://doi.org/10.1038/s41380-022-01878-z
Brain network dysfunction is increasingly recognised in Alzheimer’s disease (AD). However, the causes of brain connectivity disruption are still poorly understood. Recently, neuroinflammation has been identified as an important factor in AD pathoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945c69de6b909d9cb4585070a99b192a
https://doi.org/10.1038/s41380-022-01878-z
https://doi.org/10.1038/s41380-022-01878-z
Autor:
Vargas-Soria, Maria, Ramos-Rodriguez, Juan Jose, del Marco, Angel, Hierro-Bujalance, Carmen, Carranza-Naval, Maria Jose, Calvo-Rodriguez, Maria, van Veluw, Susanne J., Stitt, Alan W., Simó Canonge, Rafael, Bacskai, Brian J., Infante-Garcia, Carmen, Garcia-Alloza, Monica, Universitat Autònoma de Barcelona
Publikováno v:
Scientia
Vargas-Soria, M, Ramos-Rodriguez, J J, Del Marco, A, Hierro-Bujalance, C, Carranza-Naval, M J, Calvo-Rodriguez, M, Veluw, S J V, Stitt, A W, Simó, R, Bacskai, B J, Infante-Garcia, C & Garcia-Alloza, M 2022, ' Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimer's disease and type two diabetes ', Fluids and Barriers of the CNS, vol. 19, 88 . https://doi.org/10.1186/s12987-022-00380-6
Vargas-Soria, M, Ramos-Rodriguez, J J, Del Marco, A, Hierro-Bujalance, C, Carranza-Naval, M J, Calvo-Rodriguez, M, Veluw, S J V, Stitt, A W, Simó, R, Bacskai, B J, Infante-Garcia, C & Garcia-Alloza, M 2022, ' Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimer's disease and type two diabetes ', Fluids and Barriers of the CNS, vol. 19, 88 . https://doi.org/10.1186/s12987-022-00380-6
Background: While aging is the main risk factor for Alzheimer´s disease (AD), emerging evidence suggests that metabolic alterations such as type 2 diabetes (T2D) are also major contributors. Indeed, several studies have described a close relationshi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27dff62dae6c6c93aec488b267ce1a7e
https://hdl.handle.net/10481/78314
https://hdl.handle.net/10481/78314
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific reports, Vol. 11, No 1 (2021) P. 19412
Scientific Reports
Scientific reports, Vol. 11, No 1 (2021) P. 19412
Alzheimer’s disease (AD) is characterized by amyloid (Aβ) protein aggregation and neurofibrillary tangles accumulation, accompanied by neuroinflammation. With all the therapeutic attempts targeting these biomarkers having been unsuccessful, the un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f2ec98232d859e6506cec0b1c4790a
https://doaj.org/article/1fd7e2b173d64bf296cc67fcccdb9cd1
https://doaj.org/article/1fd7e2b173d64bf296cc67fcccdb9cd1
Autor:
Gemma Shireby, Emma L. Dempster, Stefania Policicchio, Rebecca G. Smith, Ehsan Pishva, Barry Chioza, Jonathan P. Davies, Joe Burrage, Katie Lunnon, Dorothea Seiler Vellame, Seth Love, Alan Thomas, Keeley Brookes, Kevin Morgan, Paul Francis, Eilis Hannon, Jonathan Mill
Publikováno v:
Nature Communications, 13(1):5620. Nature Publishing Group
Alzheimer’s disease (AD) is a chronic neurodegenerative disease characterized by the progressive accumulation of amyloid-beta and neurofibrillary tangles of tau in the neocortex. Utilizing extensive neuropathology data from the Brains for Dementia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16873a0809cedd83824c0ec2697bd79e
https://doi.org/10.1038/s41467-022-33394-7
https://doi.org/10.1038/s41467-022-33394-7
Publikováno v:
Cells; Volume 11; Issue 14; Pages: 2223
Neuroinflammation is one of the core pathological features of Alzheimer’s disease (AD) as both amyloid β (Aβ) and tau monomers and oligomers can trigger the long-term pro-inflammatory phenotype of microglial cells with consequent overactivation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4248a500a8e5ce4faad212690d18ea81
https://urn.nsk.hr/urn:nbn:hr:105:515195
https://urn.nsk.hr/urn:nbn:hr:105:515195
Autor:
Gabriel Servilha-Menezes, Rui M.P. da Silva-Júnior, Melita Salkovic-Petrisic, Suélen Santos Alves, Jan Homolak, Norberto Garcia-Cairasco
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Almost 115 years ago, Alois Alzheimer described Alzheimer’s disease (AD) for the first time. Since then, many hypotheses have been proposed. However, AD remains a severe health public problem. The current medical approaches for AD are limited to sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9c906714bf33029469a2037701a83a
https://doi.org/10.3233/jad-210234
https://doi.org/10.3233/jad-210234
Autor:
Jan Homolak, Jelena Osmanovic Barilar, Melita Salkovic-Petrisic, Ana Babic Perhoc, Ana Knezovic
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 548
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 548, p 548 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 548, p 548 (2022)
SummaryThe incretin system is an emerging new field that might provide valuable contributions to the research of both pathophysiology and therapeutic strategies in the treatment of diabetes, obesity, and neurodegenerative disorders. This study aimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc3b745c1856fd0a853c582c768edd9