Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Alyxandria M Schubert"'
Autor:
Ashley D Smith, Elissa D Foss, Irma Zhang, Jessica L Hastie, Nicole P Giordano, Lusine Gasparyan, Lam Phuc VinhNguyen, Alyxandria M Schubert, Deepika Prasad, Hannah L McMichael, Jinchun Sun, Richard D Beger, Vahan Simonyan, Siobhán C Cowley, Paul E Carlson
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0223025 (2019)
Clostridium difficile (Cd) infection (CDI) typically occurs after antibiotic usage perturbs the gut microbiota. Mucosa-associated invariant T cells (MAIT) are found in the gut and their development is dependent on Major histocompatibility complex-rel
Externí odkaz:
https://doaj.org/article/6661098026ec44cda89025df50cdf9de
Autor:
Travis J Kochan, Madeline J Somers, Alyssa M Kaiser, Michelle S Shoshiev, Ada K Hagan, Jessica L Hastie, Nicole P Giordano, Ashley D Smith, Alyxandria M Schubert, Paul E Carlson, Philip C Hanna
Publikováno v:
PLoS Pathogens, Vol 13, Iss 7, p e1006443 (2017)
Clostridium difficile (C. difficile) is an anaerobic gram-positive pathogen that is the leading cause of nosocomial bacterial infection globally. C. difficile infection (CDI) typically occurs after ingestion of infectious spores by a patient that has
Externí odkaz:
https://doaj.org/article/9303ed305e1348f79fd9548a3daa1b45
Autor:
Julia D. Berkson, Claire E. Wate, Garrison B. Allen, Alyxandria M. Schubert, Kristin E. Dunbar, Michael P. Coryell, Rosa L. Sava, Yamei Gao, Jessica L. Hastie, Emily M. Smith, Charlotte R. Kenneally, Sally K. Zimmermann, Paul E. Carlson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Bacteriophage therapy is a promising approach to address antimicrobial infections though questions remain regarding the impact of the immune response on clinical effectiveness. Here, we develop a mouse model to assess phage treatment using a
Externí odkaz:
https://doaj.org/article/5e85d387a72b493dbe77a9b0cbe7b5d8
Autor:
Sahar Abubucker, Nicola Segata, Johannes Goll, Alyxandria M Schubert, Jacques Izard, Brandi L Cantarel, Beltran Rodriguez-Mueller, Jeremy Zucker, Mathangi Thiagarajan, Bernard Henrissat, Owen White, Scott T Kelley, Barbara Methé, Patrick D Schloss, Dirk Gevers, Makedonka Mitreva, Curtis Huttenhower
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 6, p e1002358 (2012)
Microbial communities carry out the majority of the biochemical activity on the planet, and they play integral roles in processes including metabolism and immune homeostasis in the human microbiome. Shotgun sequencing of such communities' metagenomes
Externí odkaz:
https://doaj.org/article/c8bebf0300734591876c8dc5a3534b24
Autor:
Nicholas A. Lesniak, Alyxandria M. Schubert, Kaitlin J. Flynn, Jhansi L. Leslie, Hamide Sinani, Ingrid L. Bergin, Vincent B. Young, Patrick D. Schloss
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT The severity of Clostridioides difficile infections (CDI) has increased over the last few decades. Patient age, white blood cell count, and creatinine levels as well as C. difficile ribotype and toxin genes have been associated with disease
Externí odkaz:
https://doaj.org/article/8b8c8c2e674346f7938d7392dab27de3
Autor:
Julia D. Berkson, Garrison B. Allen, Alyxandria M. Schubert, Kristin E. Dunbar, Michael P. Coryell, Rosa L. Sava, Yamei Gao, Claire E. Wate, Jessica L. Hastie, Sally K. Zimmermann, Paul E. Carlson
Antimicrobial resistant bacteria are an emerging and prevalent global threat with an urgent need for alternative therapies. Bacteriophage (phage) therapy is a promising approach to address these infections that has gained renewed interest in recent y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebac618625067ea0af1c0dcac2f66167
https://doi.org/10.1101/2023.01.19.523600
https://doi.org/10.1101/2023.01.19.523600
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
mSphere
mSphere
The community of microorganisms, or microbiota, in our intestines prevents pathogens like C. difficile from colonizing and causing infection. However, antibiotics can disturb the gut microbiota, which allows C. difficile to colonize. C. difficile inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6582a00b741b26ccd0773881e2039744
https://doi.org/10.1101/2020.11.16.386086
https://doi.org/10.1101/2020.11.16.386086
Autor:
Irma Zhang, Deepika Prasad, Siobhán C. Cowley, Alyxandria M. Schubert, Ashley D. Smith, Richard D. Beger, Jinchun Sun, Elissa D. Foss, Hannah L. McMichael, Nicole P. Giordano, Paul E. Carlson, Lam Phuc VinhNguyen, Vahan Simonyan, Jessica L. Hastie, Lusine Gasparyan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 9, p e0223025 (2019)
PLoS ONE, Vol 14, Iss 9, p e0223025 (2019)
Clostridium difficile (Cd) infection (CDI) typically occurs after antibiotic usage perturbs the gut microbiota. Mucosa-associated invariant T cells (MAIT) are found in the gut and their development is dependent on Major histocompatibility complex-rel
Autor:
Catherine Putonti, Alyxandria M. Schubert, Joseph Saelens, Michael Travisano, Alexander L. Kula, Jennifer Cox
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Viruses rely upon their hosts for biosynthesis of viral RNA, DNA and protein. This dependency frequently engenders strong selection for virus genome compatibility with potential hosts, appropriate gene regulation and expression necessary for a succes
Autor:
Cydney N. Johnson, Kelli L. Palmer, Anushila Chatterjee, Phat Luong, Breck A. Duerkop, Paul E. Carlson, Alyxandria M. Schubert, Karthik Hullahalli, Sara W. McBride
Enterococcus faecalis is a human intestinal pathobiont with intrinsic and acquired resistance to many antibiotics, including vancomycin. Nature provides a diverse and virtually untapped repertoire of bacterial viruses, or bacteriophages (phages), tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fe1002422292e27b11ed4f93abc3ec
https://europepmc.org/articles/PMC6529655/
https://europepmc.org/articles/PMC6529655/